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Removed in RepentanceItem icon
Added in RepentanceItem icon
Item altar
"The heavens will change you"
Table dividing line 1.png
Item ID
Character Appearance
Character appearance
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Added in Afterbirth † / Removed in Repentance(page 4, column 7, row 2)
Removed in Afterbirth †(page 4, column 7, row 2)
Added in Repentance(page 4, column 8, row 2)
Unlock Method
Zodiac Defeat Ultra Greed as The Lost
Added in Afterbirth

For a list of all zodiac signs, see Signs of the Zodiac.

Zodiac is an unlockable passive item added in The Binding of Isaac: Afterbirth.

Effects[edit | edit source]

  • Gives Isaac a random Zodiac item effect that changes each floor.

Notes[edit | edit source]

  • Getting 15►Capricorn Capricorn, 15►Cancer Cancer and 15►Libra Libra does not grant coins, bombs, keys or Soul Hearts. 15►Leo Leo will not change Isaac's size.
  • If already in possession of the item given by Zodiac, most have no effect. The only exceptions are 15►Capricorn Capricorn giving an additional +0.5 damage, and 15►Gemini Gemini giving another familiar.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • This item's appearance is a reference to the Zodiac Killer, who used the symbol as his signature.
  • This item's icon shares the almost same icon as 15►Marked Marked but white instead of red.

Seeds[edit | edit source]

PC Normal and hard modes only ZXMH RH2C (Treasure Room adjacent to spawn)

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