Binding of Isaac: Rebirth Wiki

Added in Repentance

Worm Friend is an unlockable passive item added in The Binding of Isaac: Repentance.


  • Gives Isaac a Nerve Ending Nerve Ending familiar that burrows out of the ground to grab enemies for 4 seconds. Grabbed enemies take damage over time, are slowed, and are unable to move.
    • Worm Friend deals 4 damage per tick (8 per second), for a total of 32 damage per grab.
    • Worm Friend can target and restrain bosses in addition to normal enemies, even including endgame bosses such as Ultra Greed Ultra Greed.


  • Enemies can avoid/escape being grabbed if they move fast enough, jump, or teleport.
  • Worm friend must wait 5 seconds after losing/killing/releasing its target before it can attack another enemy.
  • When playing as Tainted Lazarus Tainted Lazarus / Dead Tainted Lazarus Dead Tainted Lazarus, entering a room with Worm Friend active and then using Flip Flip to swap to the other character will keep Worm Friend active for the remainder of the room.

In-game footage[]