Binding of Isaac: Rebirth Wiki

Whore of Babylon is a passive item.

Effects[ | ]

Notes[ | ]

  • Character Eve iconEve starts with this item by default, and has the following extra effects:
    • The item is activated at one full Red HeartRed Heart or less.
    • Her damage multiplier increases from 0.75 to 1.0 when active.
  • The effect is removed after leaving a room with more than half a heart (more than one full heart for Character Eve iconEve).
  • The effect may not be immediately applied if Isaac has lost red hearts without taking damage; the effect will activate upon entering a new room.
  • The effect is always active for characters without Red HeartRed Heart containers, such as Character ??? (Character) icon??? and Character The Lost iconThe Lost, though other characters can also lose their heart containers through Devil deals or items like Collectible Guppy's Paw iconGuppy's Paw or Collectible Abaddon iconAbaddon.
  • III - The EmpressIII - The Empress grants a similar effect to Whore of Babylon for the current room which does stack with Whore of Babylon.
    • Stacking The Empress on Whore of Babylon either via multiple cards or multiple activations of Collectible Blank Card iconBlank Card increases damage by the number of uses squared, e.g. +1.5 * 2 * 2 total damage bonus for using the card on top of activated Whore of Babylon.

Synergies[ | ]

Interactions[ | ]

  • (except in Rebirth) Character Keeper iconKeeper: As Keeper cannot have half of a Coin Heart, this item has no effect on him.
  • (in Repentance) Rotten HeartRotten Hearts: Counts as a full Red Heart for the purposes of this item, rendering it impossible to activate (except for Character Eve iconEve).
  • Collectible Whore of Babylon iconWhore of Babylon: No further effect when multiple copies are acquired.

In-game Footage[ | ]

Gallery[ | ]

Trivia[ | ]

  • Upon obtaining the Whore of Babylon effect, a popup displaying the text "What a horrible night to have a curse" appears on-screen. This can be disabled in the game options.
  • In the original The Binding of Isaac, Whore of Babylon gave a higher stat increase just for the room it was activated in, with +2.16 damage and +0.36 speed.
  • The Whore of Babylon is an evil creature mentioned in the Book of Revelations.
  • This item is used in Darkness Falls (challenge #4).