Binding of Isaac: Rebirth Wiki
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(in Repentance)

Vasculitis is a passive item added in The Binding of Isaac: Repentance.

Effects[ | ]

  • Upon killing an enemy, 1 - 16 tears are released from them in random directions.
    • The amount of tears released from an enemy is based on the enemy's health, and is not affected by Isaac's damage, nor the number of tears hit.
    • These tears are red in coloration, regardless of Isaac's tears, but will inherit the coloration of applied status effects.
  • Burst tears will do set damage per floor. The formula for this is: (3.2 + 0.3 x stage).

Notes[ | ]

  • If an enemy is killed while affected by a status effect, the burst tears will inflict the corresponding effect.
  • Homing, range and shot speed do not affect Vasculitis.
  • Released tears can be difficult to distinguish from enemy shots, especially from enemies which split in to burst shots upon death such as Red Boom FlyRed Boom Fly and light blue champions.
  • All forms of damage will cause an enemy to release tears.

Interactions[ | ]

  • Ace Cards: Enemies that are turned into pickups can’t release tears.
  • Dark EsauDark Esau: Enemies killed by Dark Esau release fire mind tears
  • Collectible E. Coli iconE. Coli/Collectible Flush! iconFlush!: Enemies that are turned into poop can’t release tears.
  • Collectible Fire Mind iconFire Mind: Not recommended. Vasculitis' tears can explode, with great potential to harm Isaac.
  • Freeze Effects: Enemies that die from being frozen can’t release tears.

In-game footage[ | ]


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