Vasculitis is a passive item added in The Binding of Isaac: Repentance.
Effects[]
- Upon killing an enemy, 1 - 16 tears are released from them in random directions.
- The amount of tears released from an enemy is based on the enemy's health, and is not affected by Isaac's damage, nor the number of tears hit.
- These tears are red in coloration, regardless of Isaac's tears, but will inherit the coloration of applied status effects.
- Burst tears will do set damage per floor. The formula for this is: (3.2 + 0.3 x stage).
Notes[]
- If an enemy is killed while affected by a status effect, the burst tears will inflict the corresponding effect.
- Homing, range and shot speed do not affect Vasculitis.
- Released tears can be difficult to distinguish from enemy shots, especially from enemies which split in to burst shots upon death such as
Red Boom Fly and light blue champions. - All forms of damage will cause an enemy to release tears.
Interactions[]
- Ace Cards: Enemies that are turned into pickups can’t release tears.
- Burn: Burning enemies release fire mind tears.
- Poison: When a poisoned enemy dies, the released tears are tinted green and will poison other enemies.
- E. Coli/Flush!: Enemies that are turned into poop can’t release tears.
- Fire Mind: Not recommended. Vasculitis' tears can explode, with great potential to harm Isaac.
- Freeze Effects: Enemies that die from being frozen can’t release tears.
In-game footage[]
 The Binding of Isaac: Rebirth
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