Binding of Isaac: Rebirth Wiki

Added in Repentance

Vade Retro is an unlockable activated item added in The Binding of Isaac: Repentance.


  • While held, enemies leave behind small, red ghosts on death; using the item causes the ghosts to explode, dealing damage to nearby enemies and destroying nearby enemy projectiles. The explosions will not destroy rocks or other obstacles.
    • The damage exploding ghosts deal is equal to 3 + 0.04x the health of the enemy the ghost spawned from + ((floor-1)x0.5), and each explosion can hit the same enemy up to 4 times. Blast radius increases the more powerful the explosion is.
      • Enemies with high health, such as champion enemies, minibosses, and bosses will leave behind a larger ghost that creates three explosions.
  • Using the item will insta-kill any enemy that has the 'ghost' tag and is at 50% or less HP, including bosses.
  • Can also detonate the player's ghost after their death, dealing 200 flat damage to nearby enemies.



  • The Book of Belial The Book of Belial + Birthright Birthright as Judas Judas / Dark Judas Dark Judas: Instead of exploding on the spot, souls home in on nearby enemies and explode on contact, similarly to Purgatory Purgatory. The souls deal 2 * Judas's damage up to 3 times and destroy projectiles.
  • Book of Virtues Book of Virtues: No wisps are created when using Vade Retro. Instead, ghosts created by enemies very slowly move and shoot tears in the same direction Isaac is shooting. The ghosts' tears deal 3.5 damage, and are fired once every second.

In-game footage[]


  • The item's name refers to the Latin phrase "Vade Retro Satana", a phrase commonly uttered during exorcisms which roughly translates to "Stay back, Satan."
  • This item's ability could be a reference to the Nuclear Throne character Melting, who has a similar ability.
    • This is further reinforced by the fact that more powerful enemies leave larger ghosts that explode into 3 small blasts; in Nuclear Throne, larger enemies' corpses would explode in a similar fashion.
  • Using the item to detonate Isaac's ghost is another parallel to Nuclear Throne's Melting and his ability, he was also able to use his ability one last time after death to explode his own corpse.
  • The Exorcist Exorcist creates red ghosts that are identical to those created by Vade Retro. These ghosts can even be blown up if Isaac has the item.