Binding of Isaac: Rebirth Wiki
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(in Repentance)

Vade Retro is an unlockable activated item added in The Binding of Isaac: Repentance.

Effects[ | ]

  • While held, enemies leave behind small, red ghosts on death; using the item causes the ghosts to explode, dealing damage to nearby enemies and destroying nearby enemy projectiles. The explosions will not destroy obstacles, move pickups, or damage Isaac.
    • The damage exploding ghosts deal is equal to 3 + 0.04x the health of the enemy the ghost spawned from + ((floor-1)x0.5), and each explosion can hit the same enemy up to 4 times. Blast radius increases the more powerful the explosion is.
      • Enemies with high health, such as champion enemies, minibosses, and bosses will leave behind a larger ghost that creates three explosions.
    • Isaac will also leave a ghost upon death, which deals 200 flat damage if detonated.
  • Using the item will instantly kill any enemy that has the 'ghost' tag and is at 50% or less HP, including bosses.

Notes[ | ]

Synergies[ | ]

  • Collectible The Book of Belial iconThe Book of Belial + Collectible Birthright iconBirthright as Character Judas iconJudas / Character Dark Judas iconDark Judas: Instead of exploding on the spot, souls home in on nearby enemies and explode on contact, similarly to Collectible Purgatory iconPurgatory. The souls deal 2 * Judas's damage up to 3 times and destroy projectiles.
  • Collectible Book of Virtues iconBook of Virtues: Ghosts very slowly move and shoot tears in the same direction Isaac is shooting. The ghosts' tears deal 3.5 damage, and are fired once every second.

Interactions[ | ]

In-game footage[ | ]

Trivia[ | ]

  • The item's name refers to the Latin phrase "Vade Retro Satana", a phrase commonly uttered during exorcisms which roughly translates to "Stay back, Satan."
    • This phrase (and its initials) are commonly engraved around crucifixes or the Saint Benedict Medal.
    • The item's sprite directly represents the reverse side of said medal (which carries the phrase).
  • This item's effects could be a reference to the Nuclear Throne character Melting, who has a similar activated ability.
    • This is further reinforced by the fact that more powerful enemies leave larger ghosts that explode into 3 small blasts; in Nuclear Throne, larger enemies' corpses would explode in a similar fashion.
    • The ability to detonate Isaac's ghost is also similar to Melting being able to use his ability one last time after death to explode his own corpse.
  • The ExorcistExorcist creates red ghosts that are identical to those created by Vade Retro. These ghosts can even be blown up if Isaac has the item.


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