Fixed The Visage's attacks to use a consistent red color scheme
Added unique item costumes to Tainted Lilith's fetus
Slightly tweaked the color of the Womb to be easier on the eyes
Updated graphics for ???'s only friend and Big Fan to be more consistent with Boom Flies and other variants
Techstone (Tech+Brimstone) lasers now have a large and giant variant similar to Brimstone lasers
Gameplay changes[ | ]
Tainted Azazel's beam now has a reduced duration unless he holds Brimstone
Tainted Azazel now sneezes automatically when charging instead of when releasing a partial charge
Hitting enemies with Tainted Azazel's sneeze cuts the remaining charge time in half
Hitting enemies with Tainted Azazel's sneeze inflicts them with a Brimstone Curse which makes them more vulnerable to Brimstone attacks and causes them to explode when killed by Brimstone
Tainted Eve's clots are no longer lost when recalled by Sumptorium if she has full health, instead they will drop to the ground next to her
Tainted Eve's clots now start with 15 HP when spawned and slowly decay down to 1 HP (5 HP for non-red hearts)
When playing as Tainted Lazarus, all items that spawn as part of a room layout (such as a treasure room or a shop) now have an alternate form which can be accessed using Flip, even after they have been picked up
Tainted Eden no longer rerolls on self inflicted damage (such as blood donations and curse rooms)
Tainted Eden no longer rerolls on fatal damage
Updated Tainted Cain's recipe system to allow golden pennies, golden pills, golden batteries and poop pickups
Tainted Cain's crafting recipes are now slightly more consistent (high quality pickups are more likely to yield high quality items)
Most of Tainted Cain's crafting recipes are now generated based on the seed of the current run, aside from a few fixed recipes
Tainted Forgotten is now thrown by releasing the attack buttons if picked up while charging an attack
Bag of Crafting now yields a random item instead of Breakfast when its result would normally be an item that hasn't been unlocked yet
Picking up items granted by Satanic Bible now counts as taking a devil deal (disabling future angel rooms)
Devil deals costing 1 heart and 2 soul hearts can now be taken if the player only has 1 heart container and no soul hearts
Devil deals can now be taken for free when under the Lost's curse (obtained by touching a white fire place or using Soul of the Lost), however this will cause other purchasable items in the room to disappear
Glass Cannon no longer breaks on self inflicted damage (such as blood donations and curse rooms)
Increased invincibility frames from Holy Mantle to 1 second (from 0.5)
IBS now behaves like a charged attack similar to Kidney Stone, but does not prevent the player from attacking when fully charged
Golden Troll Bombs now explode less often when coming in contact with the Beast
Notched Axe now consumes a soul charge per swing as Bethany after running out of durability (charges only get consumed if the swing hits an enemy or destroys something)
Notched Axe now creates bridges when breaking rocks next to pits
'M now rerolls Notched Axe when it runs out of durability
Increased the price of higher tier items in Angel shops from 15 to 30
Devil rooms are now more likely to have items for sale
Capped the proc rate of Ghost Pepper and Bird's Eye to 50% (holding both removes the cap)
Removed a redundant range increase granted by Sacred Heart and Godhead (this was originally needed to counteract the shot speed decrease)
Converter now has 3 room cooldown
The Hermit? now converts sacks into 7 pennies
Treasure rooms can now be encountered in the Seeing Double challenge
Mama Mega! now has a more intuitive interaction with golden bombs: using it will now consume a golden bomb if the player has one, allowing it to be used again
Suplex! now scales in damage and area of effect with the player's size
Blood Puppy will no longer try to attack the player when they are unable to move
Mirrors can no longer be broken by tear effects (such as Sulfuric Acid and Terra)
Anima Sola can now chain up to two targets if the player has Car Battery, if only one valid target is present it will be chained for twice the duration
Challenge trophies and giant chests now spawn with a pickup cooldown to prevent accidentally ending a run
Pop! tears will now start falling to the ground after bouncing off each other 8 times
Lemegeton now spawns item wisps from randomized pools (Treasure, Boss and Shop pool), with a 25% chance to pick the same pool as the current room
Little Baggy no longer affects pocket items that are neither pills nor cards (such as runes)
Heartbreak can no longer kill the player on pickup
Reviving after dying from having 100% broken hearts now removes 1 broken heart to prevent situations where the player would be still alive despite having no health
Dark Arts now only grants its temporary damage buff to Dark Judas and Tainted Judas
Damage buff granted by Dark Arts now decays faster the higher it is, but no longer decays while Dark Arts is active
Binge Eater now gives -0.03 speed per food item held
Binge Eater + Breakfast now increases range and shot speed (instead of range and speed)
Binge Eater + Dessert now increases damage and shot speed (instead of damage and speed)
Reduced the size of Lost Soul’s hitsphere
Sigil of Baphomet no longer triggers from stalagmites being destroyed in the Beast fight
Expansion Pack can no longer trigger Metronome or D infinity
Psy Fly now enters a brief cooldown period after reflecting a certain number of projectiles (it's still really good don't worry)
Guppy's Eye now displays the contents of Shopkeepers
Pulsing red champions now only heal enemies that are on the same team as them (perma-charmed enemies will only heal other perma-charmed enemies)
Morningstars can now sometimes spawn with an alternate facial expression
The Mausoleum can now be entered for free when under the Lost's curse
Bad Trip and Health Down can no longer be obtained from pills when under the Lost's curse
Golden hearts now only break from taking damage, or when the player no longer has enough hearts to fit all of them
Heart container overflow is now tracked for the purpose of full rerolls, this prevents unfair loss of heart containers when rerolling HP up items away (especially with Keeper)
20/20 no longer adds an extra shot when combined with The Inner Eye or Mutant Spider, instead cancels out the firerate decrease they grant (extra copies of 20/20 add 1 extra shot per copy)
Mega Mush now grants more invincibility frames after its effect expires
Spirit Shackles now grants more invincibility frames after revival
The random item effect granted by Modeling Clay is now seeded per room
Glyph of Balance no longer causes soul hearts to drop when playing as the Lost
Rebalanced payout chances from Sanguine Bond, stepping on the spikes now counts as intentional self damage (no damage penalties)
The Stars? no longer attempts to remove starting items
Curse of the Tower no longer triggers on damage taken from blood donation machines and devil beggars (but still triggers on other forms of intentional self damage such as IV Bag)
Curse of the Lost can no longer be encountered in the Red Redemption challenge
Losing flight now temporarily grants the Bible effect for the current room if the lack of flight would cause the player to be stuck otherwise
Fixed a bug causing crawlspaces to always lead to the Error room even when they should lead to a black market
Fixed TMTRAINER replacing important progression items
Fixed Soul Locket not granting stat ups when picking up soul hearts as the Lost
Fixed Dream Catcher showing incorrect items and bosses on certain levels (such as Greed Mode levels and the Void)
Fixed Decap Attack being usable while Isaac's head is in mid air
Fixed Recall causing the Forgotten's body to hover in the air with Car Battery
Fixed an exploit with the Forgotten which allowed taking infinite items from the Death Certificate area
Fixed Lil Abaddon not scaling with BFFs
Fixed Brimstone dealing one less damage tick than intended
Fixed several orbitals doing less contact damage than intended
Fixed invisible mirrors and devil room doors which could appear along walls where a door should not be present
Fixed Ludovico tears periodically getting destroyed in sidescrolling sections
Fixed red chests forcing the devil room to be initialized when opened, regardless of whether they contain a teleport to the devil room or not (this sometimes caused angel rooms not to generate properly)
Fixed treasure rooms in the mirror dimension counting as treasure rooms for the purpose of calculating Planetarium spawning chance
Fixed battery bums not giving charges to Tainted Forgotten when touched by his soul
Fixed battery bums not being able to recharge Book of Virtues
Fixed Luna light beams granting their stat bonus to the wrong character when playing as Tainted Forgotten
Fixed The Emperor? being able to create final boss fights when used in Caves II or Depths II (or equivalent floors)
Fixed The Emperor? creating a bugged Monstro fight when used in Gehenna and the Blue Womb
Fixed Genesis giving a lot more items than intended when multiple copies of the same items are owned
Fixed Genesis giving less items than intended when used by characters with multiple bodies (such as Jacob and Esau)
Fixed Genesis duplicating starting items from challenges and not removing Damocles and Missing No
Fixed Vanishing Twin not working correctly when fighting Great Gideon
Fixed the bottom right corner of closet rooms having no collision (this could rarely result in entities getting stuck there)
Fixed Star of Bethlehem crashing the game in challenge runs ending at Mega Satan
Fixed wisps spawned by Book of Virtues + Fortune Cookie not updating the player's luck stat
Fixed Urn of Souls spawning wisps when opened or closed with Book of Virtues
Fixed Guppy's Paw, Potato Peeler and Sharp Key generating wisps for free with Book of Virtues
Fixed Dull Razor killing the player when used under the Lost's curse (white fire/Soul of the Lost)
Fixed Dr. Fetus + Marked + Eye of the Occult not moving fired bombs towards the crosshair
Fixed Dr. Fetus + Rocket in a Jar always throwing rockets to the right when playing as the Forgotten
Fixed Dead Cat always setting the player's max HP to 1 even after being dropped and picked back up (this mainly affected Tainted Eden and Tainted Isaac)
Fixed several bugs related to rotten hearts with Tainted Magdalene
Fixed Haemolacria not working with the Forgotten's bone and similar melee attacks
Fixed rockets fired by Dr. Fetus + Rocket in a Jar not flying in the correct direction after passing through Angelic Prism
Fixed Dr. Fetus bombs being able to knock each other around after passing through Angelic Prism
Fixed a softlock caused by jumping down a trapdoor with Mega Mush while having flight
Fixed Dark Arts affecting friendly enemies and projectiles
Fixed speed upgrades being only half as effective on Tainted Forgotten
Fixed Tainted Forgotten immediately dying upon being revived as a different character
Fixed ???'s birthright doubling HP downs
Fixed an infinite loop caused by Haemolacria + Sad Bombs + Dr. Fetus
Fixed the full screen effect from Dogma's death animation not going away if the player teleports out of the room before the animation finishes
Fixed familiars not firing towards the crosshair when the player has Eye of the Occult and Technology/Brimstone
Fixed Clicker not spawning/removing Tainted Forgotten's Soul
Fixed a crash caused by becoming Tainted Isaac with Clicker
Fixed not being able to Flip when becoming Tainted Lazarus with Clicker
Fixed Butter spawning extra items with Damocles
Fixed items dropped by Butter being affected by auto-rerolling abilities such as Glitched Crown
Fixed Guppy's Eye sometimes leaving item previews behind when a chest or sack gets removed
Fixed Dead Eye not working correctly with the Forgotten's bone
Fixed daily runs featuring the Forgotten, Bethany or Jacob and Esau briefly displaying Apollyon as the starting character during the loading screen
Fixed not being able to consume an item with Void right after picking it up from a pedestal if certain active items were previously consumed (such as Smelter)
Fixed Tractor Beam getting visually cut off too early when hitting the top wall of the room
Fixed Esau Jr causing instant death when used as the Lost
Fixed a crash caused by certain items interacting with Mom's Knife + Tiny Planet
Fixed I Found Pills using the wrong graphics when obtained with any skin color other than Isaac's default color
Fixed Jacob and Esau’s stats clipping into the Hard/Greed mode icons
Fixed Tainted Azazel's Brimstone beam not becoming stronger when picking up Brimstone
Fixed being able to extend the duration of Berserk indefinitely by taking damage while having no health
Fixed The Fool? rarely removing all of the player's hearts
Fixed The Empress? removing all but half of a heart when the effect expires for certain characters
Fixed several indestructible enemies missing the "noreroll" tag
Fixed Rotten Gapers not having a looping idle head animation
Fixed a rare case where Delirium's death animation would never end, softlocking the game
Fixed Gnawed Leaf statue visual having a slightly oddly shaped head
Fixed Dr Fetus and Epic Fetus costumes using outdated graphics when given to Dark Judas
Fixed a crash caused by Purgatory when the owner of a Purgatory ghost stops existing before it explodes
Fixed Lil Conquest spawning locusts way more often than intended
Fixed the Forgotten's bone not being duplicated properly by Multidimensional Baby and Angelic Prism
Fixed straight lasers not respecting their range when damaging grid entities (this caused Technology Zero and Extension Cord to destroy distant poops or TNT from a distance without actually touching them)
Fixed Mother not stopping her looping sounds when teleporting out of the boss room
Fixed Dark Esau getting instantly killed by bosses that kill all spawned enemies on death (such as Mom's Heart)
Fixed Dark Esau preventing Mega Satan from progressing to his next phase
Fixed Hush sometimes spawning projectiles after dying
Fixed Tainted Boom Flies dying without exploding if killed while poisoned or burning
Fixed Ultra Greed's boss armor not resetting properly after spinning or guarding
Fixed item pedestals in boss rooms always containing multiple items in co-op, even if the pedestal wasn't spawned as a room clear reward (i.e. Moving Box, Mystery Gift, or any item that can spawn item pedestals)
Fixed Tainted Lazarus not always being able to open the “special” door in Depths 2
Fixed Tainted ??? being able to donate infinite bombs to bomb beggars if he somehow manages to obtain bombs
Fixed Tainted Jacob's co-op ghost turning into a glitched Isaac head when going to the next floor
Fixed Tainted Eden not having a randomized haircut
Fixed being able to delete any enemy or boss by holding them with Suplex right before the effect of Berserk runs out
Fixed a few exploits which allowed Found Soul's death to be bypassed
Fixed How To Jump preventing the player from attacking until they hit the ground
Fixed dying as Jacob and Esau in co-op not triggering a game over
Fixed co-op ghosts dealing much less damage than intended
Fixed some teleport animations in co-op causing the player to become permanently non-solid if interrupted by another player leaving the room
Fixed the Forgotten being able to collect pickups as a co-op ghost by using his bone
Fixed items not being given back properly when entering and leaving an abandoned mineshaft as a co-op ghost
Fixed Tainted Bethany rarely losing Lemegeton when a Polydactyly wisp is destroyed
Fixed full rerolls removing Holy Mantle shields and preventing Dark Esau from spawning for the rest of the floor
Fixed multi-shot Ludovico tears crashing the game when removed by weapon modifiers such as Mom's Knife or Brimstone
Fixed crawlspaces not being colored properly during the Ascent
Fixed a few rare crashes caused by too many lasers being on screen
Fixed Lachryphagy tears sometimes accumulating much more damage than intended
Fixed Chub, C.H.A.D and Carrion Queen segments detaching in Greed mode
Fixed certain boss fights spawning hearts and stopping the music prematurely, such as Matriarch or Delirium
Fixed Tarot Cloth quadrupling the effect of The Hierophant?, The Lovers? and Temperance? instead of simply doubling it
Fixed stat bonuses from Redemption, Candy Heart and Soul Locket not being retained when saving and resuming a run
Fixed Tainted Lilith's fetus getting duplicated when saving and resuming a run
Fixed Tainted Lilith's umbilical cord sometimes rendering behind her body when facing left or right
Fixed way too many issues with Esau Jr
Fixed a softlock caused by killing Chimera's body while it is picking up its head
Fixed Alabaster Box absorbing the black hearts granted by Judas' Shadow, potentially causing death
Fixed Lemegeton being able to give the Bible when holding the Rosary
Fixed a potential softlock when using The Moon? to teleport into an ultra secret room connected to a regular secret room
Fixed lock blocks being breakable by Notched Axe, Sulfuric Acid, and other rock breaking effects (they are supposed to be breakable only by bombs + Broken Padlock)
Fixed extra copies of Dark Esau not disappearing when going to the next floor in the Red Redemption challenge
Fixed a crash caused by Esau gaining Birthright when using Soul of Jacob and Esau
Fixed helpers spawned by Soul of the Forgotten and Soul of Jacob and Esau being able to touch ending chests, softlocking the game
Fixed Tainted Cain being able to go down to 0 hearts from taking devil deals without dying
Fixed the Exorcist having an unobtainable Bestiary entry
Fixed the wrong portrait showing if the player is killed by Scourge’s tendrils
Fixed a hitsphere from Scourge’s tendrils lingering if Scourge is killed during certain attacks
Fixed a crash caused by some of Mother’s attacks being destroyed/deflected
Fixed thrown haunted chests causing damage when Spirit Sword hits them
Undocumented Changes[ | ]
The ornament that adorns the Planetarium door was moved one pixel to the left and therefore centered.
Holding "R" to reset a run will gradually fade the screen to black before resetting the run. If R is let go during the fadeout time, it stops the fade and the run is not reset. Overall, this makes each reset take roughly 0.2 seconds longer.
When playing asTainted Lazarus, the Active Item of both of his forms now charge upon room completion. Previously, items would only charge upon room completion for Tainted Lazarus's currently active form, effectively making any active item have double its charge time.
Donation machines now give increased money when bombed, to compensate for them only being able to be destroyed once per run. This is especially useful on early floors, as it makes it much easier to purchase a 15 cent item.
Tainted Samson has a new mechanic such that if he uses Suplex! on an enemy at the end of his berserk state, it will deal extra amounts of damage and cause a Mama Mega! effect. (This uses two new animations called "SuperLeapUp" and "SuperLeapDown".)
The reason for this was due to a bug where if Tainted Samson's berserk ended while he was Suplexing, the said enemy would simply disappear, causing a softlock against some bosses
Sausage now gives a +6.9% Devil/Angel Room chance and a +6.9% Planetarium chance.
Paschal Candle now increments correctly after clearing a room with Tainted Lazarus (before, the Flip effect took priority and Paschal Candle never had an opportunity to increment).
Some items and trinkets with the lazarussharedglobal item tag are now shared between both forms of Tainted Lazarus. This includes items that map parts of the floor such as the Compass, items that increase devil/angel deal chance such as Black Candle, and items/trinkets that spawn new or altered rooms on each floor such as Voodoo Head. Items that grant a shared effect and a stat boost (such as Pentagram, which grants a damage increase and increases devil deal chance), will not transfer the stat increases between forms.
The changes to the price of certain items in an Angel shop (The Stairway) also applies to the prices of those items in Angel Rooms in general for Tainted Keeper.
Fixed Tainted Isaac's special inventory being temporarily invisible after quitting and reloading a run.
Fixed Tainted Jacob becoming permanently unable to recover from his Lost form after quitting and reloading a run.
The player the user is controlling in "netstart" co-op now has a pink outline for increased visibility.
Glass Eye, 
The Binding of Isaac: Rebirth
