Ultra Pestilence

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Ultra   Pestilence
In-game appearance

Base HPStage HP
1800
0
Table dividing line 1.png
Entity ID
951.20
Table dividing line 2.png
Found In
Boss
Stage Home icon.png
Table dividing line 3.png
Dropped Items
None
Added in Repentance

Ultra Pestilence is a boss added in The Binding of Isaac: Repentance and is the second of the Ultra Harbingers fought before The Beast.

Behavior[edit | edit source]

Ultra Pestilence spawns with a swarm of flies that hover around itself. In its first phase, Ultra Pestilence has two attacks which it alternates between.

  • Ultra Pestilence fires a large projectile in an arc at Isaac's position. Upon landing in the lava below, it creates a poisonous cloud pillar that will damage Isaac if he stands inside for too long, creates a pillar of projectiles that shoot upwards from the lava, and creates three additional projectiles that shoot upwards from the lava on both sides of the pillar. Ultra Pestilence uses this attack three times before using its other attack.
  • Ultra Pestilence fires a large maggot from its eye which flies across the screen, wrapping around three times. Before it completes a fourth wrap, it reverses direction, wrapping around three more times before reentering Ultra Pestilence's eye.

During its second phase, Ultra Pestilence loses its head, naturally generates flies around itself and uses two attacks.

  • Ultra Pestilence fires a spray of projectiles which rain down on the area in front of it.
  • Rarely, Ultra Pestilence's steed will spawn a ball of flies which moves towards Isaac. Attacking this ball of flies will spawn additional flies.

Gallery[edit | edit source]


Bosses Boss Monstro.png
Chapter 1
Stage The Basement icon.pngStage The Cellar icon.pngStage Burning Basement icon.png
GeminiStevenBlighted OvumDingleThe Duke of FliesFamineGurglingsThe HauntLarry Jr.MonstroPinWidowThe FallenThe Headless Horseman
DangleLittle HornRag ManTurdlings
Baby Plum
Chapter 1.5
Stage Downpour icon.pngStage Dross icon.png
Lil BlubWormwoodThe RainmakerMin-MinClogColostomiaTurdlet
Chapter 2
Stage The Caves icon.pngStage The Catacombs icon.pngStage Flooded Caves icon.png
FistulaChubC.H.A.D.Carrion QueenDark OneGurdyGurdy Jr.The HollowThe HuskMega FattyMega MawPeepPestilencePolycephalusThe WretchedThe FallenThe Headless Horseman
The ForsakenThe FrailThe Stain
Big HornRag Mega
Bumbino
Chapter 2.5
Stage Mines icon.pngStage Ashpit icon.png
Reap CreepTuff TwinsHornfelGreat GideonSingeThe ShellThe Pile
Chapter 3
Stage The Depths icon.pngStage Necropolis icon.pngStage Dank Depths icon.png
The AdversaryThe BloatThe CageThe GateMonstro IIGishLokiMask of InfamyWarThe FallenThe Headless HorsemanMom
Brownie
Sisters Vis
Reap CreepThe Pile
Chapter 3.5
Stage Mausoleum icon.pngStage Gehenna icon.png
The SirenThe HereticThe VisageThe Horny BoysMomMom's Heart
Chapter 4
Stage The Womb icon.pngStage Utero icon.pngStage Scarred Womb icon.png
BlastocystThe BloatConquestDaddy Long LegsTriachnidDeathLokiiMama GurdyMr. FredScolexTeratomaThe FallenThe Headless HorsemanMom's HeartIt Lives
Sisters VisThe Matriarch
???
???
Hush
Corpse
Stage Corpse icon.png
ChimeraThe ScourgeRotgutMother
Chapter 5
Stage Sheol icon.pngStage Cathedral icon.png
SatanIsaac
Chapter 6
Stage Dark Room icon.pngStage The Chest icon.png
???The LambMega Satan
The Void
Stage The Void icon.png
Delirium
Home
Stage Home icon.png
DogmaThe BeastUltra DeathUltra FamineUltra PestilenceUltra War
Greed Mode
Ultra Greed
Ultra Greed
Ultra Greedier
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets