Binding of Isaac: Rebirth Wiki
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(in Afterbirth † and Repentance)

Trisagion is an unlockable passive item added in The Binding of Isaac: Afterbirth † (Booster Pack #4).

Effects[ | ]

  • Tears are replaced with piercing white blasts of light.
    • Blasts deal 33% of the regular tear damage, but can hit the same enemy multiple times.
    • Blasts decrease in size until disappearing.
      • Despite the blasts decreasing in size after passing through obstacles, this is aesthetic as the blast will only damage enemies adjacent to the obstacle.
    • (except in Repentance) Blasts do not knock back enemies.

Notes[ | ]

  • Since the blasts can strike one enemy multiple times, low shot speed can be very beneficial whereas high shot speed may lower effective damage.
    • Walking backward while firing can allow tears to move slower, making it useful for increasing damage output.
  • Items that grant a high Tears rate, such as Collectible Soy Milk iconSoy Milk, can cause the light beams to significantly obstruct visibility, which can further be exacerbated by items such as Collectible Fruit Cake iconFruit Cake causing rapid color and size change.
  • With only Trisagion, Isaac with base stats will deal about 18 damage per second on an unmoving, gaper-sized enemy, which is almost double Isaac's base DPS of 9.5. 1.32 shot speed will reduce DPS of Trisagion to about 14.

Synergies[ | ]

  • Collectible 8 Inch Nails icon8 Inch Nails / BlisterBlister / Collectible Pisces iconPisces: Adds knockback to blasts, which can not only significantly repel enemies when used correctly, it can deal a high amount of damage to enemies unable to escape the knockback.
  • Collectible Chocolate Milk iconChocolate Milk: Fully charged Trisagion blasts deal 4 times more damage, exceeding Isaac's normal damage.
  • (in Repentance)Collectible Cricket's Body iconCricket's Body: Original blast shoots four white tears in a cross pattern during its travel time and four blast tears in a cross pattern at the end of its range. Only the original blast splits.
  • (in Repentance) Collectible Euthanasia iconEuthanasia / Collectible Explosivo iconExplosivo / Collectible Head of the Keeper iconHead of the Keeper / Collectible Holy Light iconHoly Light / Nose GoblinNose Goblin / Collectible Sinus Infection iconSinus Infection: Beams can apply the effects on each damage tick, potentially triggering them in rapid succession.
  • Collectible Evil Eye iconEvil Eye: Eyes will fire beams. Occasionally causes Trisagion beams to stay static in the air for a few seconds, dealing damage to enemies that come in contact with them.
  • Collectible Godhead iconGodhead: Although the damaging aura isn't visible, it still exists and is not affected by Trisagion's damage reduction. Still grants homing effect and shot speed down which can be very beneficial.
  • GuppyGuppy: As it hits multiple times, it spawns multiple flies per tear making it very strong.
  • (except in Repentance)Collectible Haemolacria iconHaemolacria: Both Trisagion and Haemolacria fire at the same time; Isaac's tears do not keep the spectral attribute despite the sprite being changed. The tears keeps their piercing effect.
    • (in Repentance) Haemolacria becomes one big Trisagion beam that splits into more beams when it reaches its max range.
  • (in Repentance)Collectible Hemoptysis iconHemoptysis: Enemies hit by the sneeze will gain a curse that increases the damage the blasts deal to 0.66x and +3 flat damage (instead of just x0.33). Enemies who die to the blasts under the curse will damage and spread the curse to nearby enemies. Since the flat damage ignores the multiplier, this is a huge increase to Isaac's damage.
    • Hemoptysis + Collectible Soy Milk iconSoy Milk/(in Repentance)Collectible Almond Milk iconAlmond Milk/(in Repentance)Collectible 20 20 icon20/20: The flat damage increase ignores the multiplier reductions, which results in a massive increase in damage.
  • Homing tears: Tears slow down and stay on top of the enemy, doing continuous damage.
  • (in Repentance)Collectible Jacob's Ladder iconJacob's Ladder: Small electric arcs generate from the blast every tick.
  • Collectible The Ludovico Technique iconThe Ludovico Technique: The beam becomes controllable, still dealing reduced damage but at a very high rate.
  • (in Repentance)Collectible Mucormycosis iconMucormycosis: The spore effect can stack multiple times on the same enemy.
  • Collectible My Reflection iconMy Reflection: In addition to the usual effect, lengthens the Trisagion blasts into short flexible beams for a much larger damage-dealing area.
  • Collectible Mysterious Liquid iconMysterious Liquid: Causes a large trail of creep. The effect stacks, which causes heavy damage (even to Boss Hush ingameHush).
  • (in Repentance)Collectible Ocular Rift iconOcular Rift: Creates multiple rifts as the projectile pierces enemies.
  • (in Repentance)Collectible Pop! iconPop!: Every damage tick will shoot out a Pop! tear. Trisagion shots will also hover in the air longer than normal.
  • (except in Repentance) Collectible Proptosis iconProptosis: Base damage is increased by the expected amount and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.
    • (in Repentance) Blasts now deal 2x Isaac's damage instead of 0.33x. Damage only slightly decreases in the front of the blast.
  • (in Repentance)Collectible Spirit Sword iconSpirit Sword: The sword will shoot Trisagion beams instead of energy beams, with the Trisagion beams having increased damage.

Interactions[ | ]

Overrides Trisagion:

Overridden by Trisagion:

Other interactions:

  • (except in Repentance)Collectible Bob's Rotten Head iconBob's Rotten Head: Not recommended as it explodes multiple times before reaching its target, dealing explosive damage and knockback to Isaac.
    • (in Repentance)Shoots a white blast of light instead of the head that pierces through enemies, and causing explosions when it contacts an enemy (if not killing it at the first tick), an obstacle, or when it runs out of range. One tick of the beam deals 33% of Bob's Rotten Head's damage to enemies, but the resulting explosion every tick deals full damage.
  • Collectible Compound Fracture iconCompound Fracture: Split blasts are not generated on hitting enemies, only on obstacles and walls.
  • (except in Repentance)Collectible Cricket's Body iconCricket's Body: Split blasts are not generated on hitting enemies, only on obstacles, walls, and the floor.
  • Collectible Fire Mind iconFire Mind: Tears still ignite enemies, but no longer have a chance to explode.
  • (except in Repentance)Collectible Flat Stone iconFlat Stone: Blasts continually disappear and reappear as they "bounce". The bounces deal 25% splash damage based on Isaac's base damage, but the blasts cannot do their damage while they're disappearing, leading to an overall reduced efficiency.
    • (in Repentance) Blasts no longer disappear.
  • Collectible Glass Cannon iconGlass Cannon / (in Repentance)Collectible Isaac's Tears iconIsaac's Tears / Collectible Tammy's Head iconTammy's Head: Trisagion does not gain additional damage.
  • (except in Repentance)Collectible Ipecac iconIpecac: Beams will now travel through obstacles and maintain their piercing effect dealing 33% of regular damage to enemies they come in contact with, but won't explode on hit. The Ipecac explosion will happen once the beam runs out of range or hits a wall and will deal damage equal to Isaac's damage.
    • (in Repentance) Keeps Ipecac's stats and shoots an exploding Trisagion beam. The beam explodes while in contact with an obstacle or an enemy that it does not kill on the first tick, resulting in an excellent synergy with Collectible Pyromaniac iconPyromaniac or Collectible Host Hat iconHost Hat. One tick of the beam deals 33% of Ipecac's damage to enemies, but the resulting explosion every tick deals full damage.
      • Warning: In the fight with (in Repentance) Boss The Beast ingameThe Beast, Trisagion will lose its straight shot path and go at an extreme Ipecac arc instead, which is almost guaranteed to hit any even somewhat nearby rock spire and leading to self damage, making the fight significantly more difficult.
  • (except in Repentance)Collectible Jacob's Ladder iconJacob's Ladder: Electric arcs are not generated on hitting enemies, only on obstacles and walls.
  • (except in Repentance)Collectible Lachryphagy iconLachryphagy: The blasts will slow down and float like Lachryphagy tears and eventually burst, but can not consume each other.
    • (in Repentance) Blasts have greatly reduced range, but constantly generates Lachryphagy tears, with one shot alone being capable of bursting a tear.
  • Collectible A Lump of Coal iconA Lump of Coal: Nearly no effect; increases damage by around 5% when the hit is dealt by the tip of the blast. Makes the blasts absorb light, making it difficult to see anything while Curse of DarknessCurse of Darkness is present.
    • A Lump of Coal + Collectible My Reflection iconMy Reflection: As the beam is longer, the amount of extra damage at the tip can be up to around 50%.
  • Collectible Multidimensional Baby iconMultidimensional Baby: The baby cannot duplicate Trisagion blasts.
  • Collectible The Parasite iconThe Parasite: Split blasts are not generated on hitting enemies, only on obstacles and walls.
  • (in Repentance)Collectible Playdough Cookie iconPlaydough Cookie: Rather than applying the effect to each individual tear, all beams will share the same color and change simultaneously every tick.
  • (except in Repentance)Collectible Pop! iconPop!: The blasts will slow down and float like Pop! tears, but will not bounce off each other.
  • (in Repentance)Collectible Sharp Key iconSharp Key: Thrown keys become Trisagion blasts and no longer cause enemies to drop chest contents on kill.
  • Collectible Technology Zero iconTechnology Zero: Unless Isaac has shooting familiars, Technology Zero will not function. Familiars' tears will be connected to the blasts with electricity, however.

In-game Footage[ | ]

Trivia[ | ]

  • Trisagion is based on this Steam Workshop item by x Wyvern x and TRPG, originally known as Lightshot.
  • The name is a reference to one of the oldest Christian hymns.
  • The design of Trisagion appears to be that of Borromean rings, a Christian symbol of the Trinity.

Gallery[ | ]


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