Binding of Isaac: Rebirth Wiki
(except in Rebirth)

The ShopThe Shop[]

All Boss Waves[]

Boss The Forsaken portrait
The Forsaken Needs to be unlocked
Super Greed
Super Greed

Boss Wave 1 Specific[]

Boss Monstro portrait Boss Pin portrait
Boss Widow portrait
Boss Famine portrait
Monstro Pin Widow

Famine Needs to be unlocked

Boss Chub portrait
Boss The Hollow portrait
Boss The Bloat portrait
Boss The Cage portrait
Chub The Hollow The Bloat The Cage
Boss Mask of Infamy portrait
Boss Monstro II portrait
Boss Daddy Long Legs portrait
Boss Teratoma portrait
Mask of Infamy Monstro II Daddy Long Legs Teratoma
Boss Triachnid portrait
Boss Death portrait
Boss Conquest portrait
Triachnid Needs to be unlocked Death Needs to be unlocked Conquest Needs to be unlocked
Greed
Super Envy
Greed Super Envy
Uriel
Gabriel
Uriel Needs to be unlocked Gabriel Needs to be unlocked

Boss Wave 2 Specific[]

Boss Rag Man portrait
Boss Carrion Queen portrait
Boss The Husk portrait
Boss Polycephalus portrait
Rag Man Needs to be unlocked Carrion Queen The Husk Polycephalus
Boss The Frail portrait
Boss The Stain portrait
Boss The Gate portrait
Boss The Pile portrait
The Frail Needs to be unlocked The Stain Needs to be unlocked The Gate The Pile (in Repentance)
Boss The Matriarch portrait
Boss Conquest portrait
Boss Headless Horseman portrait
The Matriarch (in Afterbirth † and Repentance) Needs to be unlocked Conquest Needs to be unlocked Headless Horseman Needs to be unlocked (Head Only)
Greed
Greed

Nightmare Wave Specific[]

Boss Blighted Ovum portrait
Boss The Frail portrait
Boss The Stain portrait
Boss Mask of Infamy portrait
Blighted Ovum The Frail Needs to be unlocked The Stain Needs to be unlocked Mask of Infamy
Gabriel
Gabriel Needs to be unlocked

Notes[]

  • A wave consisting of 2 GrubGrubs with 7 segments each can spawn for the Boss Wave 2.
  • An extremely rare (0.1 weight) wave consisting of 11 ShopkeeperShopkeepers and a FlyFly can spawn for the Nightmare Wave.