Binding of Isaac: Rebirth Wiki

The Negative is an unlockable passive item.

Effects[ | ]

  • If the character has half a red heart or no red hearts after taking damage, it triggers Collectible The Necronomicon iconThe Necronomicon effect, damaging all enemies in the room.
  • Allows entrance into the Dark RoomDark Room after beating Boss Satan ingameSatan in SheolSheol by touching the chest.
  • (in Repentance) +1 damage.
  • (in Repentance) Opens A Strange Door A Strange Door in DepthsDepths II and its variants that leads to MausoleumMausoleum/GehennaGehenna II.
    • Unlike with the Dark Room entrance, The Negative gets consumed by the door and vanishes from Isaac's inventory.

Notes[ | ]

  • This item is a guaranteed drop from Boss Mom ingameMom, if unlocked. Will drop alongside Collectible The Polaroid iconThe Polaroid, provided they are both unlocked. However, they are mutually exclusive: Once one of them is picked up, the other one will disappear.
    • With the use of a teleportation item and either a 5 pip Dice RoomDice Room or a Collectible Forget Me Now iconForget Me Now, or (in Repentance)Collectible R Key iconR Key, both The Polaroid and The Negative or multiple copies of The Polaroid or The Negative can be obtained.
    • With (in Repentance) Character Jacob and Esau iconJacob and Esau, proper alignment of both characters can enable picking up both The Polaroid and The Negative.
    • With frame-perfect timing and a bomb, it is possible to pick up both The Polaroid and the Negative.
  • The Negative always triggers when taking damage as characters who lack heart containers, such as Character Azazel iconAzazel and Character Tainted Azazel iconTainted Azazel (by default), Character ??? (Character) icon??? and Character Tainted ??? iconTainted ??? (permanently), (in Repentance) Character Dark Judas iconDark Judas and Character Tainted Judas iconTainted Judas (permanently) Character The Forgotten iconThe Forgotten (only as the soul), Character Tainted Forgotten iconTainted Forgotten (permanently), Character Dead Tainted Lazarus iconDead Tainted Lazarus(by default), Character Tainted Bethany iconTainted Bethany (permanently) or any other character who has chosen to trade away their heart containers in deals with the Devil, Black MarketBlack Markets, or with Collectible Guppy's Paw iconGuppy's Paw or (in Afterbirth † and Repentance)Collectible Potato Peeler iconPotato Peeler. It will also trigger if the character has only half of a red heart left.
  • The Negative will be the rightmost item after defeating Mom, in case Curse of the BlindCurse of the Blind is active.
  • (except in Repentance) It is possible to obtain two Negatives by obtaining one as an Character Eden iconEden starting item.
  • Obtaining multiple copies of The Negative does not cause its effect to stack.
  • As with all items crucial to story progress (Collectible Key Piece 1 iconKey Piece 1 and Collectible Key Piece 2 iconKey Piece 2, (in Repentance)Collectible Knife Piece 1 iconKnife Piece 1 and (in Repentance)Collectible Knife Piece 2 iconKnife Piece 2, (in Repentance)Collectible Dad's Note iconDad's Note, and (in Repentance)Collectible Dogma iconDogma), this item has protection from full-run rerolls. It does not, however, share the immunity (in Repentance)Collectible Dad's Note iconDad's Note has to D6-type rerolls and (in Afterbirth † and Repentance)Collectible Void iconVoid.

Synergies[ | ]

  • (in Repentance)A Missing PageA Missing Page / (in Repentance)Collectible Missing Page 2 iconMissing Page 2: Increases the damage from 40 to 80.
    • A Missing Page + Missing Page 2: The damage increase stacks for a total of 120 damage.

In-game Footage[ | ]

Trivia[ | ]

  • The Negative allows access to the Dark Room, which is also the name of a room used to develop photos (Darkroom).
  • A negative is a piece of film with an image imprinted on it and developed, and light can be shone through it to imprint a positive image on photographic paper. A negative has inverted hues and luminosity.