Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

The Negative is an unlockable passive item.


  • If the character has half a red heart or no red hearts after taking damage, it triggers 15►The Necronomicon The Necronomicon effect, damaging all enemies in the room.
  • Allows entrance into the Dark Room Dark Room after beating Satan in Sheol Sheol by touching the chest.
  • Added in Repentance +1 damage.
  • Added in Repentance Opens A Strange Door in Depths Depths II and its variants that leads to Mausoleum Mausoleum/Gehenna Gehenna II.
    • Unlike with the Dark Room entrance, The Negative gets consumed by the door and vanishes from Isaac's inventory.



  • Added in RepentanceA Missing Page A Missing Page / Added in Repentance15►Missing Page 2 Missing Page 2: Increases the damage from 40 to 80.
    • A Missing Page + Missing Page 2: The damage increase stacks for a total of 120 damage.

In-game Footage[]


  • The Negative allows access to the Dark Room, which is also the name of a room used to develop photos (Darkroom).
  • A negative is a piece of film that's been used to take a photograph but hasn't been developed into a finished photograph. A negative has inverted hues as well as inverted lightness.
    • Because of the instant nature of Polaroid film versus regular film, however, one would usually never see the Negative of a Polaroid and a dark room would not be required to develop one, which calls into question its relation to 15►The Polaroid The Polaroid. However, this could probably explain the fact that both items can't be picked up together in a run (unless 15►Forget Me Now Forget Me Now or a 5-pip Dice Room is used).

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