The Necronomicon is an unlockable activated item.
Effect[]
- Upon use, deals 40 damage to every enemy in the room.
This item belongs to the 
Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.
Notes[]
- Many collectibles will produce effects similar to the Necronomicon, such as depleting a Black Heart or blocking projectiles with Dry Baby.
- The Necronomicon deals a considerable amount of damage to bosses that have multiple damageable parts, e.g. Larry Jr. and The Hollow.
- This item also does high enough damage to instantly kill most non-boss enemies.
Synergies[]
- A Missing Page / Missing Page 2: Increases the damage from 40 to 80.
- A Missing Page + Missing Page 2: The damage increase stacks for a total of 120 damage.
In-game Footage[]
Trivia[]
- The Necronomicon is a fictional grimoire appearing in the works of horror writer H.P. Lovecraft.
- A Missing Page and Missing Page 2 are both references to missing pages of the Necronomicon appearing in Evil Dead.
- The book seems to be bound in human skin, which explains the face on its cover.
- The face on the cover is another reference to The Evil Dead franchise, which has the same face on its Necronomicon.
Gallery[]
3DS The icon of The Necronomicon as seen on the lower 3DS screen.
Picture of The Necronomicon when activated.
 Books
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 The Binding of Isaac: Rebirth
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