Binding of Isaac: Rebirth Wiki

The Necronomicon is an unlockable activated item.


  • Deals 40 damage to every enemy in the room.
  • Added in Afterbirth † This item belongs to the Bookworm set. Collecting three items from this set will transform Isaac into Bookworm.


  • Many collectibles will produce effects similar to the Necronomicon, such as depleting a Black Heart Black Heart or blocking projectiles with Dry Baby Dry Baby.
  • The Necronomicon deals a considerable amount of damage to bosses that have multiple damageable parts, e.g. Larry Jr. Larry Jr. and The Hollow The Hollow.
  • This item also does high enough damage to instantly kill most non-boss enemies.


In-game Footage[]


  • The Necronomicon is a fictional grimoire appearing in the works of horror writer H.P. Lovecraft.
  • The book seems to be bound in human skin, which explains the face on its cover.
    • The face on the cover is another reference to The Evil Dead franchise, which has the same face on its Necronomicon.