Binding of Isaac: Rebirth Wiki

This article is about The Mark, not to be confused with Marked.

The Mark is a passive item.

Effects[ | ]

In-game Footage[ | ]

Trivia[ | ]

  • The Mark refers to the Mark of the Beast in the end of times prophecies (3 6's arranged in a triskelion). Without this mark, one would not be allowed to buy or sell.
  • While The Mark's icon shows the 6's facing towards the center, on Isaac's forehead the symbol appears with the 6's facing outwards.
  • Boss Loki ingameLoki has the Mark of the Beast on his forehead.