Binding of Isaac: Rebirth Wiki

Questionmarkisaac.png For the trinket with a similar name, see Monkey Paw.

The Left Hand is an unlockable trinket.



  • Removed in Repentance The effect includes Chests already spawned. Entering a room that previously contained other types of Chests while holding The Left Hand will turn them into Red Chests permanently.
    • Added in Repentance Chests that have already spawned are not converted into Red Chests.
  • It is advised to drop The Left Hand (by holding either CTRL key for few seconds, holding R2 or RT for 3 seconds on PS4 and Vita and Xbox One, respectively, or holding ZR on the New Nintendo 3DS / Nintendo Switch for a few seconds) before entering Chest Chest, as non-Red Chests always contain item pedestals on this floor, especially the 4 located in the starting room.
    • Removed in Repentance Isaac may prefer Red Chests for their possible Soul Heart Soul Hearts or Red Chest items, at the expense of guaranteed items.
    • Added in Repentance Locked Chest Locked Chests converted in Chest Chest's starting room will contain Devil Deals, potentially allowing for more powerful items, but at the cost of Hearts.
      • Red Chests found past the starting rooms of either Chest Chest or Dark Room Dark Room will contain regular Red Chest drops. Dropping the trinket before leaving the starting room is advised.
  • Added in Repentance Bomb Chest Bomb Chests are affected by The Left Hand. Added in Repentance Old Chest Old Chests and Added in Repentance Mega Chest Mega Chests are not affected.


In-game Footage[]


  • The Left Hand is a reference to occult beliefs in which the "The left hand path" is associated to black magic.
  • The Left Hand is the only item in the game with 2 separate conditions for unlocking it, being unlocked by killing Ultra Pride Ultra Pride, or by defeating ??? ??? in Chest Chest as Judas Judas


PC WJAF PQR1 (Normal room south of spawn).


Switch DBDR SJGV (First floor item room)