The Binding of Isaac: Afterbirth is the expansion to The Binding of Isaac: Rebirth. The DLC was released on October 30th, 2015 and costs $10.99/£7.99. It was released on May 10, 2016 on Xbox One and PS4.

For a list of the pre-release blog posts, see The Binding of Isaac: Afterbirth (Pre-Release).

Features

Greed Mode: A new game mode with a heavy focus on risk/reward, featuring a new ending and final boss.
Blue Womb: A new area, featuring a new ending and final boss.
Daily Runs: Daily seeded runs with online leaderboards.
Two new characters, Lilith and Keeper.
95 new items and 29 new trinkets.
New pickups, chests, pills, and cards.
10 new challenges.
4 new alternate chapters: Burning Basement, Flooded Caves, Dank Depths, and Scarred Womb.
Many new room layouts including tiny rooms, long hallways, and L-shaped rooms.
New room types like trap rooms, double treasure rooms, and closets.
New special seeds, along with a seed code combo page.
An expanded soundtrack.
An extra HUD option, allowing items picked up to be displayed on-screen.
9 new transformations.
New bosses, along with new variations of bosses introduced in Rebirth.
New monsters.
Updated item combo system.
New achievements.
New co-op babies.
An improved collection page that shows item descriptions.

Additions

Characters

Character	Lilith	Keeper
Health	Template:RedHeartTemplate:BlackHeartTemplate:BlackHeart	Template:CoinHeartTemplate:CoinHeart
Damage	3.5 (*1.00)	3.5 (*1.20)
Tears	Blindfolded
Shot Speed	Blindfolded	1
Range	Blindfolded	23.75
Speed	1.0	0.85
Luck	0	-2
Starting Pickups	None	x1 Bombs x1 Coins Store Key
Starting Item(s)	Incubus, Cambion Conception, Box Of Friends	Triple shot, Wooden Nickel

Items

95 new items were added in the expansion: 19 activated items and 76 passive items.

Activated Collectibles

Passive Collectibles

Trinkets

29 new trinkets were added in the expansion.

Pickups

Pickups & Chests

Name	Icon	Description
Gold Heart		Gold Hearts are the rarest variation of a heart. They are unlocked by completing the challenge Template:AfterbirthXXXXXXXXL. They always appear as full hearts and, once picked up, drop money the next time Isaac loses a Heart. A Golden Heart appends to the end of the health bar, surrounding it in a golden glow.
Lucky Penny		A Lucky Penny increases luck by 1 when picked up. Unlocked by donating 1 coin to the Greed Machine. Bumbo and Bum Friend are unable to pick up Lucky Pennies; they instead hover over them attempting to pick them up. Humbling Bundle does not double lucky pennies.
Sticky Nickel		A Nickel that will flip upside-down when Isaac tries to collect it. Afterwards, it will get stuck on the ground, unable to be picked up unless blasted off the ground with an explosion. Unlocked by completing Boss Rush with Keeper. It won't reduce the spawn rate of regular Nickels: rather, Pennies have an additional chance to become Sticky Nickels.
Gold Bombs		Gold bombs will not add to the player's bomb count, but when picked up, they will give the player unlimited bombs for the duration of the current floor, similarly to Golden Keys. They are unlocked by completing the challenge Blue Bomber.
Angel Chests		Angel Chests are similar in appearance to Gold Chests, except they glow bright blue instead of gold, like a soul heart. They require one key to unlock, but can be reopened a random amount of times, each time requiring another key. They can be found in Angel rooms and rarely in a normal room. Their loot is similar to Golden Chests, but they can also drop nothing upon opening. If they contain nothing or an item, they will no longer be able to be reopened.
Spike Chests	File:SpikeChest.png	Spike Chests are purple colored chests with spikes protruding from them that will deal damage to Isaac upon opening (unless he has the Holy Mantle active, which nullifies the damage, or if found in The Chest, where they are free to open). They can be rarely found upon completing a room or in greed mode shops. Their loot is similar to Brown Chests. Unlike other chests, they do not appear on the minimap.
Mystery Sack		The Mystery Sack will spawn 1-4 pickups upon touching it. Sack Head greatly increases the chances of finding sacks.

Pills

Pill	Effect
Addicted	Makes Isaac take a full heart of damage from all sources for the current room. Unlocked by completing Challenge #24: PAY TO PLAY.
Friends Till The End!	Spawns three Blue Flies.
Infested!	Destroys all poop in the room and spawns a single Blue Spider under Isaac and on each destroyed poop.
Infested?	Spawns Blue Spiders equal to the number of enemies in the room. If there are no enemies in the room, spawns 1-3 Blue Spiders.
One Makes You Small	Decreases Isaac's size and increases the pitch of his voice. This effect decreases the size of Isaac's hitbox.
One Makes You Larger	Increases Isaac's size and decreases the pitch of his voice. This effect does not increase the size of Isaac's hitbox.
Percs	Gives The Wafer effect while in the room. Unlocked by completing Challenge #24: PAY TO PLAY.
Power Pill	Activates an effect similar to The Gamekid.
Re-Lax	For a short time, poop spawns wherever Isaac moves, like Explosive Diarrhea but with poop. A higher move speed means you can touch more tiles in the same time. A pun on laxatives. Unlocked by completing Challenge #25: Have a Heart.
Retro Vision	Briefly pixelates the screen 3 times over 30 seconds.
???	Gives the Curse of the Maze effect for the remainder of the floor. The effect can stack with other curses. If no other curses are active for the floor, Curse of the Maze will appear under the level name when TAB is held. This effect cannot be negated by Black Candle. Unlocked by completing Challenge #25: Have a Heart.

Cards & Runes

Rune	ID	Icon	Message	Unlocked by completing	Effect Template:Blank Rune

Transformations

Transformation	Appearance	Transformation effect	Item	Icon	Item effect	Recharge
Bob	File:Bob Transformation.png	Isaac gains a green trail of poisonous creep. Template:Item Template:Item Template:Item Template:Item
			Conjoined	File:Baby Transformation.png	When attacking, the tumor faces shoot tears diagonally outwards, similar to the effect of The Wiz. -0.3 damage. Slightly decreases tears. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
						Fun Guy	File:Mushroom Transformation.png	+1 heart container. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
									Leviathan	File:Evil Angel Transformation.png	Flight. +2 black hearts. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
												Oh Crap	File:Poop Transformation.png	Whenever a pile of poop is destroyed, health is replenished by half a heart. Template:Item Template:Item Template:Item
Seraphim	File:Angel Transformation.png	Flight. +3 soul hearts. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
															Spun	File:Drugs Transformation.png	+2 damage. +0.15 speed. Spawns a random pill upon transformation. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
																		Yes, Mother?	File:Mom Transformation.png	Isaac gains a stationary knife that trails directly behind him. It synergizes like Mom's Knife would. Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item Template:Item
												Super Bum	File:Super Bum.png ¹	Replaces Bum Friend, Dark Bum, and Key Bum for Super Bum. He collects any of the other beggars' pickups, and offers twice the rewards. Template:Item Template:Item Template:Item

^{1: Image depicts the familiar. This transformation does not alter Isaac's appearance.}

NPCs

Monsters

Many new monsters were added in the expansion. Additionally, several new champion types were added.

Template:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:MonsterTemplate:Monster

Monster	Description

Bosses

Several new bosses were added in the expansion. Additionally, many bosses received new champion variants.


Rag Man	Little Horn	Dangle	Turdlings


The Frail	The Stain	The Forsaken	Brownie


Hush	Ultra Greed

Beggars

Bomb Bum

Bomb Bums are extremely rare, and ask for bombs. Each bomb donated has a chance to have him drop 1-2 bomb pickups or an item from the Bomb Bum Item Pool. After spawning a pedestal item, the Bomb Bum will disappear and can no longer be donated to.

Environment

Chapters

File:Burning Basement.png	File:Flooded Caves.png
Burning Basement	Flooded Caves
	File:Scarred Womb.png
Dank Depths	Scarred Womb
File:Blue Womb.png
??? (Blue Womb)

Challenges

Name	Conditions	Goal	Unlocked by	Unlocks Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg Template:Chlg

Changes