Binding of Isaac: Rebirth Wiki
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Player

Characters

Character Lilith App
Lilith
Keeper App
Keeper
Health Stat Icon Health Full red heartFull black heartFull black heart Full coin heartFull coin heart
Damage Stat Icon Damage 3.5 (*1.00) 3.5 (*1.20)
Tears Stat Icon Tears BlindfoldedBlindfolded
(+0)
+18
Shot Speed Stat Icon Shot Speed BlindfoldedBlindfolded
(1)
1
Range Stat Icon Range BlindfoldedBlindfolded
(23.75)
23.75
Speed Stat Icon Speed 1.0 0.85
Luck Stat Icon Luck 0 -2
Starting Item Icon Starting Pickup(s) None x1 bombs
Needs to be unlocked x1 coins
Needs to be unlocked (except in Rebirth)Store KeyStore Key
Starting Item Icon Starting Item(s) (except in Rebirth)Collectible Incubus iconIncubus
Needs to be unlocked (except in Rebirth)Collectible Cambion Conception iconCambion Conception
(except in Rebirth)Collectible Box of Friends iconBox of Friends
Triple shot
Needs to be unlocked (except in Rebirth)Collectible Wooden Nickel iconWooden Nickel

Transformations

1: Image depicts the familiar. This transformation does not alter Isaac's appearance.

Co-op

Special Babies

These Babies have special bonuses that will aid the player in some way.

ID Appearance Name Description
27 027 baby black Black Baby Spawns with an extra black heart.
Black Baby Defeat Mega Satan as Character Azazel iconAzazel to unlock it.
28 028 baby red Red Baby Spawns with an extra red heart.
Red Baby Defeat Mega Satan as Character Magdalene iconMagdalene to unlock it.
29 029 baby white White Baby Gives Isaac an eternal heart when it spawns.
White Baby Defeat Mega Satan as Character The Lost iconThe Lost to unlock it.
30 030 baby blue Blue Baby Spawns with an extra soul heart.
Blue Baby Defeat Mega Satan as Character ??? (Character) icon??? to unlock it.
31 031 baby rage Rage Baby Occasionally briefly increases Isaac's damage by 2.
Rage Baby Defeat Mega Satan as Character Samson iconSamson to unlock it.
32 032 baby cry Cry Baby Occasionally briefly increases Isaac's tears by 1.
Cry Baby Defeat Mega Satan as Character Isaac iconIsaac to unlock it.
33 033 baby yellow Yellow Baby Occasionally briefly increases Isaac's speed by 0.15.
Yellow Baby Defeat Mega Satan as Character Eden iconEden to unlock it.
34 034 baby long Long Baby Occasionally briefly increases Isaac's range by 2, shot speed by 0.5, (except in Repentance) and tear falling speed.
Long Baby Defeat Mega Satan as Character Lazarus iconLazarus to unlock it.
35 035 baby green Green Baby Occasionally briefly increases Isaac's luck by 2.
Green Baby Defeat Mega Satan as Character Cain iconCain to unlock it.
36 036 baby lil Lil' Baby Occasionally briefly decreases Isaac's size.
Lil' Baby Defeat Mega Satan as Character Eve iconEve to unlock it.
37 037 baby big Big Baby Occasionally briefly increases Isaac's size.
Big Baby Defeat Mega Satan as Character Lilith iconLilith to unlock it.
38 038 baby brown Brown Baby Occasionally briefly gives Isaac the Butt PennyButt Penny effect. While it is active, picking up a coin will make Isaac fart, knocking back nearby enemies.
Brown Baby Defeat Mega Satan as Character Judas iconJudas to unlock it.
39 039 baby noose Noose Baby Occasionally briefly gives Isaac the Collectible Transcendence iconTranscendence effect, granting flight.
Noose Baby Defeat Mega Satan as Character Keeper iconKeeper to unlock it.
40 040 baby hive Hive Baby Occasionally briefly gives Isaac the Collectible Hive Mind iconHive Mind effect, doubling the damage dealt by blue spiders and blue flies.
Hive Baby Earn all Hard mode Completion Marks as Character ??? (Character) icon??? to unlock it.
41 041 baby buddy Buddy Baby Occasionally briefly gives Isaac the Collectible Guillotine iconGuillotine effect, detaching Isaac's head and increasing damage and tears.
Buddy Baby Earn all Hard mode Completion Marks as Character Isaac iconIsaac to unlock it.
42 042 baby colorful Colorful Baby Upon joining, fully heals Isaac, similar to the rainbow poop effect.
Colorful Baby Earn all Hard mode Completion Marks as Character Magdalene iconMagdalene to unlock it.
43 043 baby whore Whore Baby Occasionally briefly gives Isaac the Collectible Whore of Babylon iconWhore of Babylon effect, increasing damage and speed.
Whore Baby Earn all Hard mode Completion Marks as Character Eve iconEve to unlock it.
44 044 baby cracked Cracked Baby
Cracked Baby Earn all Hard mode Completion Marks as Character Eden iconEden to unlock it.
45 045 baby dripping Dripping Baby Occasionally briefly gives Isaac Collectible Anemic iconAnemic, increasing range by 5 and causing Isaac to leave a trail of blood that damages enemies.
Dripping Baby Earn all Hard mode Completion Marks as Character Lazarus iconLazarus to unlock it.
46 046 baby blinding Blinding Baby Upon death, activates the effect of XIX - The Sun, fully restoring Isaac's red hearts, deals 100 damage to all enemies in the room, and revealing the map for the current floor.
Blinding Baby Use Collectible Blank Card iconBlank Card while holding XIX - The SunXIX - The Sun to unlock it.
47 047 baby sucky Sucky Baby Has an aura around itself that damages enemies while they are inside, similar to Collectible Succubus iconSuccubus.
Sucky Baby Earn all Hard mode Completion Marks as Character Azazel iconAzazel to unlock it.
48 048 baby dark Dark Baby Occasionally provides a brief boost to all of Isaac's stats.
Dark Baby Earn all Hard mode Completion Marks as Character Lilith iconLilith to unlock it.
49 049 baby picky Picky Baby
Picky Baby Earn all Hard mode Completion Marks as Character Cain iconCain to unlock it.
50 050 baby revenge Revenge Baby Occasionally briefly increases Isaac's damage.
Revenge Baby Earn all Hard mode Completion Marks as Character Samson iconSamson to unlock it.
51 051 baby belial Belial Baby Occasionally briefly gives Isaac the Collectible The Book of Belial iconThe Book of Belial effect, increasing damage.
Belial Baby Earn all Hard mode Completion Marks as Character Judas iconJudas to unlock it.
52 052 baby sale Sale Baby Occasionally briefly gives Isaac the Collectible Steam Sale iconSteam Sale effect, halving the prices of all shop items.
Sale Baby Earn all Hard mode Completion Marks as Character Keeper iconKeeper to unlock it.
53 053 baby goatbaby Goat Head Baby Occasionally briefly gives Isaac the Collectible Goat Head iconGoat Head effect, guaranteeing that a Devil room or angel room will open if a boss room is completed while the effect is active.
Goat Head Baby Defeat Mom's Heart on Hard mode as Character Lilith iconLilith to unlock it.
54 054 baby supergreedbaby Super Greed Baby Has the Head of the Keeper effect, firing coin tears that have a chance to spawn a coin upon hitting an enemy.
Super Greed Baby Defeat Mom's Heart on Hard mode as Character Keeper iconKeeper to unlock it.

Normal Babies

These Babies are purely cosmetic and do not have any special behaviors.

ID Appearance Name Description
233 233 baby punkboy Punkboy Baby A baby dressed as a punk rocker boy.
234 234 baby punkgirl Punkgirl Baby A baby dressed as a punk rocker girl.
235 235 baby computer Computer Baby A baby with a computer for a head.
236 236 baby mask Mask Baby A baby wearing a mask.
237 237 baby gem Gem Baby A baby that looks like it's made of crystal.
238 238 baby shark Shark Baby A baby that looks like a shark.
239 239 baby beret Beret Baby A baby that's wearing a beret.
240 240 baby blisters Blisters Baby A baby covered in blisters.
241 241 baby radioactive Radioactive Baby A sickly green baby.
242 242 baby beast Beast Baby A baby that looks like a beast.
243 243 baby dark Dark Baby A very dark baby.
244 244 baby snail Snail Baby A baby that looks like a snail.
245 245 baby blood Blood Baby A baby that looks like a drop of blood.
246 246 baby 8ball 8 Ball Baby A baby with an 8 ball for a head.
247 247 baby wisp Wisp Baby A wispy baby.
248 248 baby cactus Cactus Baby A baby that looks like a cactus.
249 249 baby loveeye Love Eye Baby A pink baby with a heart for an eye.
250 250 baby medusa Medusa Baby A baby that resembles Medusa.
251 251 baby nuclear Nuclear Baby A baby that looks like a mushroom cloud.
252 252 baby purple Purple Baby A strange purple baby.
253 253 baby wizard Wizard Baby A baby with a wizard hat.
254 254 baby earth Earth Baby A baby whose head looks like planet Earth.
255 255 baby saturn Saturn Baby A baby with a ring around its head.
256 256 baby cloud Cloud Baby A baby made of cloud.
257 257 baby tube Tube Baby A baby with a tube connecting both eyes.
258 258 baby rocker Rocker Baby A baby dressed as a rock fan.
259 259 baby king King Baby A baby with a crown.
260 260 baby coat Coat Baby A baby wearing a winter coat.
261 261 baby viking Viking Baby A baby with a Viking helmet.
262 262 baby panda Panda Baby A baby that looks like a panda.
263 263 baby raccoon Raccoon Baby A baby that looks like a raccoon.
264 264 baby bear Bear Baby A baby that looks like a grizzly bear.
265 265 baby polarbear Polar Bear Baby A baby that looks like a polar bear.
266 266 baby lovebear Lovebear Baby A baby that looks like a Care Bear.
267 267 baby hare Hare Baby A baby that looks like a rabbit.
268 268 baby squirrel Squirrel Baby A baby that looks like a squirrel.
269 269 baby tabby Tabby Baby A baby that looks like a cat.
270 270 baby porcupine Porcupine Baby A baby that looks like a porcupine.
271 271 baby puppy Puppy Baby A baby that looks like a puppy.
272 272 baby parrot Parrot Baby A baby that looks like a parrot.
273 273 baby chameleon Chameleon Baby A baby that looks like a Chameleon.
274 274 baby boulder Boulder Baby A baby made of rocks.
275 275 baby aqua Aqua Baby An aqua-blue baby.
276 276 baby gargoyle Gargoyle Baby A baby that resembles a gargoyle.
277 277 baby spikydemon Spiky Demon Baby A baby that looks like a spiky demon.
278 278 baby reddemon Red Demon Baby A baby that looks like a red demon.
279 279 baby orangedemon Orange Demon Baby A baby that looks like an orange demon.
280 280 baby eyedemon Eye Demon Baby A baby with an eye for a head.
281 281 baby fangdemon Fang Demon Baby A baby with big fangs.
282 282 baby ghost Ghost Baby A baby that looks like a ghost.
283 283 baby arachnid Arachnid Baby A baby that looks like a spider.
284 284 baby bony Bony Baby A baby that looks like a Bony.
285 285 baby bigtongue Big Tongue Baby A baby with a big tongue.
286 286 baby 3d 3D Baby A baby wearing 3D glasses.
287 287 baby suit Suit Baby A baby in a nice suit.
288 288 baby butt Butt Baby A baby with a butt for a face.
289 289 baby cupid Cupid Baby A baby that looks like Cupid.
290 290 baby heart Heart Baby A baby with a heart-shaped head.
291 291 baby killer Killer Baby A baby that looks like Jason Voorhees from the "Friday the 13th" horror movie series.
292 292 baby lantern Lantern Baby A baby that looks like Ash Williams from the Evil Dead series.
293 293 baby banshee Banshee Baby A baby that looks like a banshee.
294 294 baby ranger Ranger Baby A baby that looks like a Red Power Ranger.
295 295 baby rider Rider Baby A baby that looks like a Kamen Rider.
296 296 baby choco Choco Baby A baby made of chocolate.
297 297 baby woodsman Woodsman Baby A baby dressed as a hiker.
298 298 baby brunette Brunette Baby A baby with brown hair
299 299 baby blonde Blonde Baby A baby with blonde hair.
300 300 baby bluehair Blue Hair Baby A baby with blue hair
301 301 baby bloodied Bloodied Baby A baby covered in blood.
302 302 baby cheese Cheese Baby A baby made of cheese.
303 303 baby pizza Pizza Baby A baby made of pizza.
304 304 baby hotdog Hotdog Baby A baby that is also a hotdog.
305 305 baby hotdog Nature Baby A naked baby with a leaf.
306 306 baby borg Borg Baby A robotic baby.
307 307 baby corrupted Corrupted Baby A baby with seems to be covered by an alien life.
308 308 baby xmouth X Mouth Baby A gagged baby.
309 309 baby xeyes X Eyed Baby A comically dead baby.
310 310 baby stareyes Starry Eyed Baby A baby with starry eyes.
311 311 baby surgeon Surgeon Baby A baby ready for surgery.
312 312 baby sword Sword Baby A baby that's a sword.
313 313 baby monk Monk Baby A baby that's a monk.
314 314 baby disco Disco Baby A funky baby with an afro
315 315 baby puzzle Puzzle Baby A baby with a "Rubik's Cube" for a head
316 316 baby speaker Speaker Baby A baby that has a speaker for a head.
317 317 baby scary Scary Baby A baby that resembles Jeff the Killer.
318 318 baby fireball Fireball Baby A fireball with eyes. Possibly a reference to the fire enemy in the Donkey Kong and Mario games.
319 319 baby maw Maw Baby A baby that's just a mouth.
320 320 baby exploding Exploding Baby A baby that's a bomb.
321 321 baby cupcake Cupcake Baby A baby that's also a cupcake.
322 322 baby skinless Skinless Baby A baby without skin.
323 323 baby ballerina Ballerina Baby A baby wearing a tutu.
324 324 baby goblin Goblin Baby A baby that resembles a goblin.
325 325 baby coolgoblin Cool Goblin Baby A green baby with brown hair and cool shades.
326 326 baby geek Geek Baby A baby with black hair and nerdy glasses.
327 327 baby longbeard Long Beard Baby A baby with a long beard.
328 328 baby muttonchops Muttonchops Baby A baby with muttonchops.
329 329 baby spartan Spartan Baby A baby that resembles King Leonidas from 300.
330 330 baby tortoise Tortoise Baby A baby that resembles Vectorman from the game Vectorman
331 331 baby slicer Slicer Baby A baby that resembles Shredder.
332 332 baby butterfly Butterfly Baby A baby with butterfly wings.
333 333 baby homeless Homeless Baby A baby that resembles a homeless person.
334 334 baby lumberjack Lumberjack Baby A baby that resembles a lumberjack.
335 335 baby cyberspace Cyberspace Baby A baby that resembles something from the Tron universe.
336 336 baby hero Hero Baby A baby that resembles Red from Gunstar Heroes.
337 337 baby boxers Boxers Baby A baby that resembles Arthur from Ghosts & Goblins (in his boxers).
338 338 baby winghelmet Wing Helmet Baby A baby that resembles Opa-Opa.
339 339 baby x X Baby A baby with an X for a head.
340 340 baby o O Baby A baby with an O for a head.
341 341 baby vomit Vomit Baby A baby with vomit coming from its mouth.
342 342 baby merman Merman Baby A baby that resembles Aquaman.
343 343 baby cyborg Cyborg Baby Might be a reference to a Cyborg from a novel/movie/game?
344 344 baby barbarian Barbarian Baby A baby that resembles the Barbarian from Diablo.
345 345 baby locust Locust Baby A baby that resembles a locust.
346 346 baby twotone Twotone Baby A completely white baby with a black outline.
347 347 baby 2600 2600 Baby A baby that resembles an Atari 2600 sprite.
348 348 baby fourtone Fourtone Baby A baby with a minimal colour sprite.
349 349 baby grayscale Grayscale Baby A baby colored with several shades of gray.
350 350 baby rabbit Rabbit Baby A baby that resembles Oswald the Lucky Rabbit.
351 351 baby mouse Mouse Baby A baby that resembles an old-style Mickey Mouse.
352 352 baby critter Critter Baby A critter that looks white and hairy. Might be a reference to the movie Critters.
353 353 baby bluerobot Blue Robot Baby A baby that resembles Mega Man.
354 354 baby pilot Pilot Baby A baby that resembles Jason from Blaster Master.
355 355 baby redplumber Red Plumber Baby A baby that resembles Mario.
356 356 baby greenplumber Green Plumber Baby A baby that resembles Luigi.
357 357 baby yellowplumber Yellow Plumber Baby A baby that resembles Wario.
358 358 baby purpleplumber Purple Plumber Baby A baby that resembles Waluigi.
359 359 baby tanooki Tanooki Baby A baby that's wearing a Tanooki Suit.
360 360 baby mushroomman Mushroom Man Baby A baby that resembles Toad.
361 361 baby mushroomgirl Mushroom Girl Baby A baby that resembles Toadette.
362 362 baby cannonball Cannonball Baby A baby that resembles a Chain Chomp.
363 363 baby froggy Froggy Baby A baby that's wearing a Frog Suit.
364 364 baby turtledragon Turtle Dragon Baby A baby that resembles Bowser.
365 365 baby shellsuit Shell Suit Baby A baby wearing a Hammer Suit.
366 366 baby fiery Fiery Baby A baby wearing a Fire Suit.
367 367 baby meanmushroom Mean Mushroom Baby A baby that resembles a Goomba.
368 368 baby arcade Arcade Baby A baby that resembles Pac-Man.
369 369 baby scaredghost Scared Ghost Baby A blue ghost with a scared expression.
370 370 baby blueghost Blue Ghost Baby A baby that resembles Inky.
371 371 baby redghost Red Ghost Baby A baby that resembles Blinky.
372 372 baby pinkghost Pink Ghost Baby A baby that resembles Pinky.
373 373 baby orangeghost Orange Ghost Baby A baby that resembles Clyde.
374 374 baby pinkprincess Pink Princess Baby A baby that resembles Princess Peach.
375 375 baby yellowprincess Yellow Princess Baby A baby that resembles Princess Daisy.
376 376 baby dino Dino Baby A baby that resembles Yoshi.
377 377 baby elf Elf Baby A baby that resembles Link.
378 378 baby darkelf Dark Elf Baby A baby that resembles Dark Link
379 379 baby darkknight Dark Knight Baby A baby that resembles a Darknut
380 380 baby octopus Octopus Baby A baby that resembles an Octorok.
381 381 baby orangepig Orange Pig Baby A baby that resembles an orange Moblin.
382 382 baby bluepig Blue Pig Baby A baby that resembles a blue Moblin.
383 383 baby elfprincess Elf Princess Baby A baby that resembles Princess Zelda.
384 384 baby fishman Fishman Baby A baby that resembles a Zora.
385 385 baby fairyman Fairyman Baby A baby that resembles Tingle.
386 386 baby imp Imp Baby A baby that resembles Midna.
387 387 baby worm Worm Baby A baby that resembles Earthworm Jim.
388 388 baby bluewrestler Blue Wrestler Baby A baby that looks like the blue player in Smash TV.
389 389 baby redwrestler Red Wrestler Baby A baby that looks like the red player in Smash TV.
390 390 baby toast Toast Baby A baby that resembles Powdered Toast Man.
391 391 baby roboboy Roboboy Baby A baby that resembles Astro Boy.
392 392 baby liberty Liberty Baby A baby that resembles the Statue of Liberty.
393 393 baby dreamknight Dream Knight Baby A baby that resembles Meta Knight.
394 394 baby cowboy Cowboy Baby A baby that's wearing a cowboy outfit.
395 395 baby mermaid Mermaid Baby A baby that resembles Ariel.
396 396 baby plague Plague Baby A baby wearing a plague doctor outfit.
397 397 baby spacesoldier Space Soldier Baby A baby that resembles a Warhammer 40k Space Marine.
398 398 baby darkspacesoldier Dark Space Soldier Baby A baby that resembles a Warhammer 40k Chaos Space Marine.
399 399 baby gasmask Gas Mask Baby A baby that's wearing a gas mask.
400 400 baby tomboy Tomboy Baby A baby that resembles Sheik from the Legend of Zelda franchise.
401 401 baby corgi Corgi Baby A baby that looks like a corgi.
402 402 baby unicorn Unicorn Baby A baby that looks like a unicorn.
403 403 baby pixie Pixie Baby A baby that resembles Tinkerbell.
404 404 baby referee Referee Baby A baby wearing a referee outfit.
405 405 baby dealwithit Deal With It Baby A baby with a goatee and sunglasses.
406 406 baby astronaut Astronaut Baby A baby that's wearing an astronaut outfit.
407 407 baby blurred Blurred Baby A baby with a blur effect across its privates.
408 408 baby censored Censored Baby A baby with a censor bar across its privates.
409 409 baby coolghost Cool Ghost Baby A baby that resembles the character Shades (Sukezaemon) from Ufouria: The Saga.
410 410 baby gills Gills Baby A baby that resembles the character Gil (Jennifer) from Ufouria: The Saga.
411 411 baby bluehat Blue Hat Baby A baby that resembles the character Bop-Louie (Hebe) from Ufouria: The Saga.
412 412 baby catsuit Catsuit Baby A baby that's wearing a cat outfit. Also resembles the character Oh-Chan from Ufouria: The Saga (Japanese version).
413 413 baby pirate Pirate Baby A baby that's wearing a pirate outfit.
414 414 baby superrobo Super Robo Baby A baby that resembles Tekkaman the Space Knight.
415 415 baby lightmage Lightmage Baby A baby that resembles the white mage class from Final Fantasy.
416 416 baby puncher Puncher Baby A baby that resembles the warrior class from Final Fantasy.
417 417 baby holyknight Holy Knight Baby A baby that resembles the monk class from Final Fantasy.
418 418 baby shadowmage Shadowmage Baby A baby that resembles the black mage class from Final Fantasy.
419 419 baby firemage Firemage Baby A baby that resembles the red mage class from Final Fantasy.
420 420 baby priest Priest Baby A baby that's wearing a priest outfit.
421 421 baby zipper Zipper Baby A baby with a zipped mouth.
422 422 baby bag Bag Baby A baby with a bag over its head.
423 423 baby sailor Sailor Baby A baby that's wearing a sailor outfit.
424 424 baby rich Rich Baby A baby with a top hat and monocle.
425 425 baby toga Toga Baby A baby in an ancient Roman outfit.
426 426 baby knight Knight Baby A baby that resembles a Darknut from The Legend of Zelda.
427 427 baby blackknight Black Knight Baby A baby that resembles a black Darknut from The Legend of Zelda.



Items

95 new items were added in the expansion: 19 activated items and 76 passive items.

Activated Collectibles

Passive Collectibles

Trinkets

29 new trinkets were added in the expansion.


Pickups

Hearts

Heart Image Worth Additional Info Unlocked By
Gold Heart GoldHeart Full red heart When a Gold Heart is lost, a few coins will be dropped around you. Template:Achv

Coins

Coin Image Worth Additional Info Unlocked By
Lucky Penny File:LuckyPennyAnim.gif 1

Increases luck by 1 when picked up.

Template:Achv
Sticky Nickel File:NickelAnim.gif 5

Will flip upside-down when Isaac tries to collect it. Afterwards, it will get stuck on the ground, unable to be picked up unless blasted off the ground with an explosion.

Template:Achv

Bombs

Bomb Image Worth Additional Info Unlocked By
Gold Bomb Gold Bomb

Will not add to the player's bomb count, but when picked up, it will give the player unlimited bombs for the duration of the current floor, even if the current number of bombs is 0.

Template:Achv

Pills

ID Pill Effect
28 Needs to be unlocked Percs!

Gives Collectible The Wafer iconThe Wafer effect while in the room. Unlocked by completing Challenge #24: PAY TO PLAY.

29 Needs to be unlocked Addicted!

Makes Isaac take a full heart of damage from all sources for the current room. Unlocked by completing Challenge #24: PAY TO PLAY.

30 Needs to be unlocked Re-Lax

For a short time, poop spawns wherever Isaac moves, like Explosive Diarrhea but with poop. A higher move speed means you can touch more tiles in the same time. A pun on laxatives. Unlocked by completing Challenge #25: Have a Heart.

31 Needs to be unlocked ???

Gives the Curse of the Maze effect for the remainder of the floor. The effect can stack with other curses. If no other curses are active for the floor, Curse of the Maze will appear under the level name when TAB is held. This effect cannot be negated by Collectible Black Candle iconBlack Candle. Unlocked by completing Challenge #25: Have a Heart.

32 One makes you larger

Increases Isaac's size and decreases the pitch of his voice. This effect does not increase the size of Isaac's hitbox. (in Afterbirth † and Repentance) These pills contribute to the Stompy transformation.

33 One makes you small

Decreases Isaac's size and increases the pitch of his voice. This effect decreases the size of Isaac's hitbox.

34 Infested!

Destroys all poop in the room and spawns a single Blue Spider under Isaac and on each destroyed poop.

35 Infested?

Spawns Blue Spiders equal to the number of enemies in the room. If there are no enemies in the room, spawns 1-3 Blue Spiders.

36 Power Pill!

Activates an effect similar to Collectible The Gamekid iconThe Gamekid.

37 Retro Vision

Briefly pixelates the screen 3 times over 30 seconds.

38 Friends Till The End!

Spawns three Blue Flies.

Cards

Runes

Consumables

Chests

AngelChest Eternal Chests
  • Eternal Chests are similar in appearance to Gold Chests, except they glow bright blue instead of gold, like a soul heart. They require one key to unlock, but can be reopened a random amount of times, each time requiring another key. They can be found in Angel rooms, in I AM ERROR Rooms and rarely in a normal room. Their loot is similar to Golden Chests, but there is a 25% chance they will drop nothing upon opening. If they contain nothing or an item, they will no longer be able to be reopened.
SpikedChest Spiked Chests
  • Spiked Chests are purple colored chests with spikes protruding from them that will deal damage to Isaac upon opening unless he has the Holy Mantle active, which nullifies the damage, or if found in The Chest/Dark Room, where they are free to open. They can be rarely found upon completing a room or in greed mode shops. Their loot is similar to Brown Chests. Unlike other chests, they do not appear on the minimap.

Sacks

MysteryBag Mystery sack
  • Spawns 1-4 random pickups upon touching it. It will not drop any hearts, pills or chests, and they have an increased chance to drop batteries.

Entities

Monsters

Bosses

Boss Rag Man
Boss Little Horn
Boss Dangle
Boss Turdlings
Rag Man Little Horn Dangle Turdlings
Boss The Frail
Boss The Stain
Boss The Forsaken
Boss Brownie
The Frail The Stain The Forsaken Brownie
Boss Hush
Boss Ultra Greed
Hush Ultra Greed

Beggars

Bomb bum Bomb bum

Bomb Bums are extremely rare, and ask for bombs. Each bomb donated has a chance to have him drop 1-2 bomb pickups or an item from the Bomb Bum Item Pool. After spawning a pedestal item, the Bomb Bum will disappear and can no longer be donated to.

Environment

Chapters

Template:Stage Template:Stage
Burning Basement Flooded Caves
Template:Stage Template:Stage
Dank Depths Scarred Womb
Template:Stage
??? (Blue Womb)

Challenges

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