Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki
Tag: Visual edit
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(Added some information about what the clots are called in the modding API. May be useful to future modders.)
Tag: Visual edit
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* The achievement for unlocking Tainted Eve is "The Curdled", a possible title for the character.
* The achievement for unlocking Tainted Eve is "The Curdled", a possible title for the character.
**To ''curdle'' is to "separate or cause to separate into curds or lumps", representing Eve's blood clot familiars.
**To ''curdle'' is to "separate or cause to separate into curds or lumps", representing Eve's blood clot familiars.
*A blood clot is known by the game as a "BLOOD_BABY" in the modding API.

Revision as of 10:06, 4 June 2021

Added in Repentance

Tainted Eve is a character added in The Binding of Isaac: Repentance. She is the alternate version of Eve Eve with ragged hair, no bird, and ruined mascara as if crying. Tainted Eve is unlocked by reaching Home Home and using either the 15►Red Key Red Key or the Cracked Key Cracked Key to access a special room in one of the walls while playing as Eve.

Tainted Eve starts with 2 red hearts and 1 key, and possesses a very low base fire rate compared to other characters. Unlike her normal counterpart, Tainted Eve does not start with 15►Dead Bird Dead Bird or 15►Whore of Babylon Whore of Babylon. Instead, Tainted Eve starts with 15►Sumptorium Sumptorium in her consumable slot. After holding down the fire button for 2 seconds, a blood clot familiar that shoots tears will spawn alongside her. Each time a blood clot is spawned, half a heart is drained, and this process can be repeated as long as Tainted Eve has at least half a heart remaining. Using Sumptorium will destroy all blood clots, returning the health used to create them, and damaging enemies they pass through as they travel.

Another effect of Sumptorium is that if every remaining clot is killed and Tainted Eve only has half a heart left, she is granted a 15►Whore of Babylon Whore of Babylon-like effect and begins to use Sumptorium as a weapon that functions similar to 15►Mom's Knife Mom's Knife. The effect persists until Tainted Eve either gains health or summons a clot, though the effect will persist until the next room is entered. This effect can also be triggered if Tainted Eve summons a blood clot while having no others and is left with half a heart. While under this effect, any summoned blood clots will use a small Mom's Knife for the rest of the room.

Blood Clots

Blood clots are familiars intrinsic to Tainted Eve due to her starting item, Sumptorium. Its basic effects are shown below, but can be read in further detail on its respective page.

  • While holding the Drop/Swap Item button, Tainted Eve's clots will remain where they are instead of following her, similar to Esau Esau.
  • Tainted Eve's clot creation follow this priority: Golden > Eternal > Rotten > Red > Soul > Black > Bone Hearts.
  • Each type of heart generates a different type of blood clot:
    • Red Hearts: A red familiar with tears that deal 33% of Tainted Eve's damage.
    • Soul Hearts: A blue ???-like familiar with tears that deal 33% of Tainted Eve's damage.
    • Black Hearts: A black devil-like familiar with tears that deal 40% of Tainted Eve's damage and have a 15►Dark Matter Dark Matter effect.
    • Eternal Hearts: A white familiar with tears that deal 50% of Tainted Eve's damage and have a 15►Sacred Heart Sacred Heart homing effect.
    • Golden Hearts: A golden familiar with tears that deal 33% of Tainted Eve's damage and have a 15►Midas' Touch Midas' Touch effect.
    • Bone Hearts: A skeletal familiar with tears that deal 33% of Tainted Eve's damage and have a 15►Compound Fracture Compound Fracture effect.
    • Rotten Heart: A green familiar with tears that deal 33% of Tainted Eve's damage and have a 15►The Common Cold The Common Cold effect.
  • Upon activation, Sumptorium destroys any remaining blood clots and heals Tainted Eve for the same type of hearts that were used
  • If Tainted Eve uses 15►Sumptorium Sumptorium while there are enemies between her and the blood clots, they will deal damage on their way back.
  • Turning an Eternal Heart into a clot will prevent it from turning it into a heart container if Tainted Eve goes down a floor with it as a clot.
  • Blood clots are not affected by environmental hazards such as spikes, cobwebs or fireplaces. Cobwebs can cause the blood clots to move out of sync with Tainted Eve while she is slowed.
  • Blood clots move on the ground by default; whenever Tainted Eve gains flight, her blood clots will gain flight too.
  • In Co-Op, when Tainted Eve dies and becomes a ghost baby, her clots will remain on screen and can be controlled in the normal way, but will receive the same damage debuff. If all of them die, Tainted Eve's ghost will receive Sumptorium for the rest of the time she is dead, making her a decently damaging ghost.
  • If you are about to be hit by an attack which will kill many of your blood clots, you can save them by using Sumptorium.
  • If you take in more clots than you have space for, Eve's health will fill, and any excess health from clots will persist inside of her for 3 seconds before disappearing.
    • During this time, clots can effectively be created for free, as well as the contact damage from the traveled clots remaining active.
  • The maximum number of clots that can be present at a time appears to be 50-70. The cause for variation is unknown. When this maximum is reached, attempts to spawn any additional clots will destroy a clot summoned previously.

Unlockable Items


  • Tainted Eve's strength is proportional to how many blood clots she has: she is required to keep them around for protection, while at the same time protecting them from harm in order to keep her offense going. Because of this, her runs can go hot and cold depending on her items and drops.
  • As she is heavily geared towards turning health into familiars, an abundance of heart drops of any sort can easily grant Tainted Eve impressive room-clearing abilities. The sheer amount of blood clots will cause her to have extreme damage (due to the amount of tears being fired) and multiple "bodyguards" to block her from enemy tears.
  • Tainted Eve loses a significant amount of staying power if she has low health and few clots: she will be forced to either use her horrendous base tears, or create a small number of blood clots that may end up dying anyway, which is usually the case during the start of a run.
  • To make the most use of hearts, backtrack and use every remaining heart drop to create new clots once a floor is clear, and bomb objects that can potentially drop hearts, such as Blood Donation Machines.
  • If you are at full health, keep in mind to pick up/use any health-restoring items like Blood Bag or Full Health pills after you create clots, as it will make use of any potentially wasted heals.
  • Enemies with piercing/area of effect abilities (such as enemy 15►Brimstone Brimstone beams or 15►Ipecac Ipecac shots) are usually her biggest weakness, as they can instantly vaporize a large group of her clots or hit her when she is at half a heart. Similarly, bullet hell enemies will slowly chip away at her clots if she is careless. Thus, endgame bosses such as Delirium and Hush will usually be her hardest challenge, since Tainted Eve will start out strong, but may become completely helpless at the end without any clots.
    • Similarly, rooms with lots of obstacles can prove to be detrimental, as it will likely cause the clots to separate and make them more likely to take damage, as well as reducing Tainted Eve's damage output.
  • Tainted Eve can "reserve" heart drops by turning them into clots, and then heal herself back up afterwards. This can allow her to use self-harm sources such as Sacrifice Rooms, Curse Rooms and Blood Donation Machines more frequently. However, note that her clots will only heal however many heart containers she possesses: if she has more clots than necessary, the excess clots will be wasted and not returned. In such a case, it is usually wiser to keep her blood clots around if she has a large number of them.
  • As she is able to control how many hearts she possesses in her health, Tainted Eve can easily make use of both types of Challenge Rooms.
  • Greed Mode is difficult for Tainted Eve, as she can struggle to get momentum going on the first two floors. A strong start is one with a lot of health available. You want to generate as many clots as possible, so you can quickly kill each new wave as it appears. A handful of clots with a mild Damage or Tears Up starting item is worse than a mass of clots with base stats. Before the early bosses consider how many clots you still have. If you're only a bit low, don't be afraid to buy Red Hearts from the shop to replenish their numbers. If you're low on health, clots, and money, it may be worth activating the powerful Whore Of Babylon effect and trying to quickly kill the bosses that way. If you can survive the first two floors, and hopefully pick up some decent offensive items, then the rest of the run tends to be easier.

Favored Items

  • Because of Tainted Eve's pitiful rate of fire, she will greatly appreciate any item which can boost said stat. 15►Squeezy Squeezy and 15►Mr. Dolly Mr. Dolly are particularly good items for her, as they grant a tears up plus spare hearts to turn into clots.
  • Since Tainted Eve's clots are treated as familiars, trinkets such as Forgotten Lullaby Forgotten Lullaby and Baby-Bender Baby-Bender work to great effect. Similarly, 15►BFFS! BFFS! increases the damage of the clots, increasing Tainted Eves damage output immensely.
  • Special effect tears which scale on luck (15►The Common Cold The Common Cold) are particularly effective on Tainted Eve, especially with a large amount of clots since they use her own tears to fire. With such items, she'll also benefit from anything which boosts her Luck such as 15►Magic Scab Magic Scab and 15►Lucky Foot Lucky Foot.
  • Health Up items allow for better clot resource management and the ability to produce more at one time. Even better are items which grant both a health up and heal such as 15►Blood Bag Blood Bag, as she can turn all spare red hearts into clots while getting a full heal.
  • Items that grant increased tear knockback (such as 15►Pisces Pisces) work immensely when Tainted Eve has many clots, as they already possess high knockback when stacked.
  • 15►Adrenaline Adrenaline: Since clot generation favors Red hearts over all other types, Tainted Eve can obtain a large damage bonus with every 2 clots she generates out of her red health.
  • 15►Book of Revelations Book of Revelations: Allows Tainted Eve to generate 2 extra blue clots every 6 rooms.
  • Bloody Penny Bloody Penny: Each penny has a chance of dropping half red hearts for clot creation.
  • 15►Charm of the Vampire Charm of the Vampire: Every 13 kills allows Tainted Eve to create one blood clot.
  • Child's Heart Child's Heart: Increases the drop rate of red hearts, and thus increases the ability to make clots.
  • 15►D1 D1: Allows duplicating any spare pickups on the floor, including red hearts.
  • 15►Glowing Hour Glass Glowing Hour Glass: Can be used to prevent the loss of clots, or to avoid especially dangerous rooms.
  • Isaac's Fork Isaac's Fork: Has a chance to heal for half a heart with every cleared room, which can be used to create a clot.
  • 15►Leech Leech: Can be used to kill weak enemies and give health for more red clots.
  • 15►Lost Contact Lost Contact: With a sufficient amount of clots and/or a high enough Fire Rate, Tainted Eve and her clots can create an impenetrable wall of defense in the direction they are firing, protecting them from any and all enemy shots. This is particularly critical against bosses such as Mega Satan or Hush, who use bullet-intensive attacks.
  • 15►Libra Libra: Balances out Tainted Eve's stats and constantly remedies her extremely low tears when picking up stat upgrades.
  • Mom's Locket Mom's Locket: Using a key heals for half a heart. It additionally has the far more useful perk of turning all half heart drops into full hearts, making every heart drop more efficient.
  • 15►Sharp Straw Sharp Straw: Gives Tainted Eve a consistent method of harming an entire room of enemies. It also gives the additional benefit of potential half heart drops, which gives her some extra sustain.
  • 15►Spirit Sword Spirit Sword can be swung as fast as the button can be mashed, negating the downside of Tainted Eve's low Tears.
  • 15►Tear Detonator Tear Detonator: Detonates all of the clots' tears as well, filling the room with tears and potentially dealing massive damage.
  • 15►Tractor Beam Tractor Beam: Causes all tears fired by blood clots to follow the beam, making it significantly easier to hit all of their shots consistently.
  • 15►Yum Heart Yum Heart/15►Yuck Heart Yuck Heart/15►Little C.H.A.D. Little C.H.A.D.: Allows Tainted Eve to generate extra red/green clots every few rooms.
  • 15►Placenta Placenta: Given enough patience, allows Tainted Eve to generate theoretically infinite blood clots.
  • Maggy's Bow: Thanks to the doubled healing, you can generate two clots from half a heart, four clots from a full heart, and eight clots from a double heart, making for less risk in creating clots and healing up in general and making for a much quicker amassing of a clot army.
  • Prayer Card: With proper play, you can have many Eternal Heart clots as well as max red hearts to get even more bang for your buck.

Disfavored Items

  • Clots cannot benefit from any items that prevent taking damage, potentially making items such as 15►Book of Shadows Book of Shadows, 15►Host Hat Host Hat, or 15►My Little Unicorn My Little Unicorn worse defensive options than normal.
  • 15►Abaddon Abaddon: Replaces all red heart containers with black hearts, making it much harder to consistently generate clots without soul heart generation or more health upgrades after pickup.
  • 15►Birthright Birthright: Currently has no effect.
  • 15►Crown of Light Crown of Light: Rarely active, since firing will automatically drain red hearts.
  • 15►Marked Marked: Tainted Eve will constantly fire unless the player presses the drop trinket button, which can unintentionally cause her to create clots even if the player does not wish to.
  • 15►Satanic Bible Satanic Bible: While the extra Black Heart is tempting for more special clots, the Boss Room item will be replaced by a Devil Deal, putting a dent on Tainted Eve's total ability to create clots on the long term.
  • 15►Technology 2 Technology 2: The laser will apply to Tainted Eve but not her clots. She will also suffer a loss to her already pathetic rate of fire, which can be more palpable with more familiars.
  • 15►Maw of the Void Maw of the Void/15►Revelation Revelation: Due to their fixed 2.5 second activation times, their effects cannot be activated without draining at least half a heart.
  • Be wary of any items that replace normal tears with a charged attack. If Tainted Eve’s fire rate is high, it may require the loss of a significant amount of damage to summon a blood clot during a fight. If it is low, she may be forced to summon one or more blood clots in order to attack.
  • 15►Kidney Stone Kidney Stone: While activated, there is no way to prevent blood clots from spawning until the effect has worn off, and will quickly drain Tainted Eve's health as the effect is active.



  • The achievement for unlocking Tainted Eve is "The Curdled", a possible title for the character.
    • To curdle is to "separate or cause to separate into curds or lumps", representing Eve's blood clot familiars.
  • A blood clot is known by the game as a "BLOOD_BABY" in the modding API.


Isaac CharNav New.png Maggy CharNav New.png Cain CharNav New.png Judas CharNav New.png BB CharNav New.png Eve CharNav New.png Samson CharNav New.png Azazel CharNav New.png Lazarus CharNav New.png Eden CharNav New.png Lost CharNav New.png


Tainted Isaac CharNav New.png Tainted Maggy CharNav New.png Tainted Cain CharNav New.png Tainted Judas CharNav New.png Tainted BB CharNav New.png Tainted Eve CharNav New.png Tainted Samson CharNav New.png Tainted Azazel CharNav New.png Tainted Lazarus CharNav New.png Tainted Eden CharNav New.png Tainted Lost CharNav New.png Tainted Lilith CharNav New.png Tainted Keeper CharNav New.png Tainted Apollyon CharNav New.png Tainted Forgotten CharNav New.png Tainted Bethany CharNav New.png Tainted Jacob CharNav New.png

The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
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