Binding of Isaac: Rebirth Wiki
Added in Repentance

Tainted Characters are different versions of already existing characters, both in terms of gameplay and design. They are considered completely new characters, raising the total of characters to 34 in The Binding of Isaac: Repentance.

They are unlocked by using the Red Key Red Key or a Cracked Key Cracked Key on the left side of the wall in the hall before Mom's Bedroom in Home Home with each non-Tainted Character.

They can be accessed via the Character select menu by pressing E. The menu will appear a lot more worn, with tears in the wallpaper.

As the Tainted Characters, certain unlocks require multiple completion marks: Satan Satan, Isaac Isaac, The Lamb The Lamb, and ??? ??? all contribute to just one unlock, and Boss Rush Boss Rush and Hush Hush account for one unlock as well. On top of this, Tainted Characters lack an unlock for defeating Mom's Heart Mom's Heart/ It Lives It Lives on Hard Mode, Ultra Greed Ultra Greed, completing all Hard mode completion marks, and naturally lack a corresponding Tainted Character unlock. This results in each only having 7 unlocks, rather than the standard 15.



  • The Red Key Red Key is guaranteed for the first time Isaac enters Home Home, and is unlocked by opening the chest in Mom's bedroom for the first time. After that, Mom's Chest will pull from its own item pool which includes Mom-related items, as well as the Red Key rarely.
  • In order to guarantee an unlock on subsequent trips to Home Home, Isaac must leave a trinket in either a Treasure Room Treasure Room or a Boss Room Boss Room. When he reaches the Ascent after picking up Dad's Note Dad's Note, the trinket that was left will transform into a Cracked Key Cracked Key in the corresponding room.
  • To unlock these characters, Isaac does not need to defeat Dogma Dogma or The Beast The Beast on the run he opens the closet. They will be unlocked as soon as he touches them (or lets a Bomb Bomb explode next to them), regardless of what happens during the following battles.