Tainted Cain

 

Stats

Damage	3.5 (*1.00)
Tears	+0
Shot Speed	1
Range	6.5
Speed	1.30
Luck	0

Starting Items

Pickups	1 key Bag of Crafting
Items	None

Unlock Method
Use the Red Key or Cracked Key in Home as Cain

Tainted Cain is a character added in The Binding of Isaac: Repentance. He is the alternate version of Cain. Tainted Cain is unlocked by reaching Home and using either the Red Key or the Cracked Key to access a special room in one of the walls while playing as Cain.

Tainted Cain starts with 2 heart containers, 1 key, and the Bag of Crafting. Tainted Cain's Bag of Crafting is stored in the pill/card slot, meaning it is used with the pill/card key, is not dropped when picking up other active items, and cannot be discarded through any means. Tainted Cain is still able to hold one pill/card, in addition to the item.

Tainted Cain can't get items (except story items) through any means other than the Bag of Crafting, and attempting to do so will transform the item into an assortment of consumables. If this is done in a room with a special loot pool, one of the dropped consumables will be guaranteed to be the one which biases crafting recipes towards that pool.

Crafting an active item when already holding one will also transform the old active item into consumables instead of dropping it, following the same above rules.

Notes

• A list of recipes for craftable items using the most common components is available.
• Items related to story plots are not affected and can be taken as normal, including:
  • The Polaroid
  • The Negative
  • Key Piece 1
  • Key Piece 2
  • Broken Shovel
  • Broken Shovel
  • Mom's Shovel
  • Knife Piece 1
  • Knife Piece 2
  • Dad's Note
  • Dogma

Item & Strategy Notes

• Many alternate ways of getting pedestal items, such as Shops or Devil Rooms, become irrelevant or outright detrimental when playing as Tainted Cain. Taking a Devil Deal only has the immediate benefit of dropping Black Hearts, which can be accomplished without spending Heart Containers through replacing Tainted Cain's Active Item while present in the Devil Room. As such, it is often more beneficial to skip the first Devil Room and instead potentially get free materials from a later Angel Room.
  • Shops do, however, have the use of purchasing Cards or Pills, which can then be dropped on the ground and used as ingredients.
• Cards should be checked for there effects before being put in the bag of crafting, senice a few may be more beneficial to use then part of a recipe.
• It may be beneficial to leave room rewards and pedestal item drops for a later time, then returning to craft items out of the more expensive materials once more are gathered.
• Players should be careful about crafting range-increasing items, as these will offset the hitbox of the Bag of Crafting's swing. This can, with a high enough range stat, make it very difficult to grab crafting materials precisely.
• However, keep in mind the base range of the Bag of Crafting's swing is usually enough to get pickups behind rocks.
• Tainted Cain starting with Bag of Crafting but not occupying his Activated Item slot makes it very powerful for reaching Achievements, as long as you know the recipes including, because you don't need to depend on random number generation to get these items.
  • Achievements that require collecting all items.
  • Achievements that require collecting a certain number of items of a certain category.
  • Tainted Cain's completion marks can be achieved by crafting powerful combinations of items, such as Gnawed Leaf (which can be created with the most common items so can usually be crafted in the first floor) and familiars that attack on their own like Daddy Longlegs. Selective crafting may make it hard to beat the time limits for Boss Rush and ???, but you can craft the alternate items to unlock those levels, as well as the alternate items to unlock the golden door in The Chest or The Dark Room. You can also craft these item combos and then switch characters using items like Lazarus' Rags or Clicker to handle a completion mark that you were finding particularly difficult.

Good Items

Of course it isn't expected for the player to learn every individual crafting recipe, though it may be beneficial to memorize or have a few noteworthy cheap recipes at the ready.

• Portable Slot is arguably the cheapest item that can be crafted, able to be crafted with 8 pennies. Not only can it be used as a way to mill off coins in exchange for other materials and generate a large number of pickups in one room, a second one can easily be crafted on top of the first in any special room to create the pickup that corresponds to its item pool. For example, replacing your active item with a slot machine in a Secret Room will always generate a bone heart.
• D20 can be crafted from common pickups, and is a great Active Item to hold onto, allowing Tainted Cain to reroll massive amounts of pickups anytime a pedestal item is broken, potentially into chests which can give even more.
• Mitre, while somewhat expensive, can be useful in the long term, as Soul Hearts are a common requirement for recipes.
• Contract From Below can give you access to significantly larger amounts of pickups throughout a run if crafted early.
• Glitter Bombs can allow for additional pickup generation, especially if combined with Dr. Fetus, Epic Fetus, or No. 2. Of these three, No. 2 is the cheapest to craft and typically the most convenient to utilize in this fashion, though it is also quite slow.
• Diplopia may be useful to generate large amounts of pickups in one room, especially special rooms.
• Eden's Blessing can be crafted repeatedly to make any character start with excessive amounts of items. (Stacks up to 10 items).
• Goat Head / Eucharist are expensive to craft, but can give you consistent access to black hearts and/or eternal hearts, making it easier to craft Devil and/or Angel pool items.
• Duality allows much more freedom to utilize black hearts and eternal hearts as you see fit, especially when combined with Goat Head or Eucharist.
• Mama Mega! is very expensive, but can be used to force entry into Boss Rush and Hush. Due to how slow and methodical Tainted Cain typically is, this item can be incredibly useful for getting completion marks.
• Schoolbag can be a useful investment to make, as it allows for the player to carry an Active Item they intend to use, as well as an Active Item to be turned into materials in special rooms.
• Dad's Lost Coin can be crafted to generate Lucky Pennies for more expensive recipes.
• Moving Box allows you to more easily control what kinds of pickups you get. By putting a pedestal item in the box and placing it back down inside of a special room, you can guarantee the pickup associated with that room. This eliminates the need to constantly be spending resources crafting new active items, but requires a 4-room recharge between uses, making it a tradeoff.
• Void and Abyss can be used as a way to boost Tainted Cain's stats or damage output in rooms with multiple pedestals, due to direct stat up items being a bit hard to come by.
• Birthright has some relatively cheap recipes, and is one of the most important items for Tainted Cain, doubling the amount of pickups each pedestal item turns into.
• Rock Bottom is very cheap to craft, requiring only 4 pennies, 3 keys, and a bone heart. Because you can guarantee this is one of the first items encountered in a run, it can be the backbone of an extremely powerful synergy of only a handful of items, such as Red Stew and Soy Milk.
• Options? will give you a much larger variety of ingredients throughout a run. It should be noted that you cannot put both pickups generated by Options? into the Bag of Crafting. You will only take the closest one to you, and the further pickup will disappear.
• Red Stew is a great panic craft, able to be made out of one key, one bomb, and six pennies. If a run is struggling, this can be a good item to extend it.
• Tooth and Nail is a very easy way to access Curse Rooms for free, allowing consistent generation of rotten hearts.
• R Key takes quite a bit of thought to craft, though allows for Tainted Cain to continue a run almost indefinitely if crafted repeatedly, potentially earning every Completion Mark outside of Greed Mode in a single run.
• Myosotis, while not craftable, can be a good trinket to keep an eye out for, as it allows the transport of 4 pickups to the next floor.
• Alabaster Box is dirt cheap, requiring only one soul heart and seven pennies. It is fully charged upon crafting and can be used to generate infinite pickups.

Bad Items

• The D6, Eternal D6, and Spindown Dice serve no purpose due to Tainted Cain being unable to pickup anything they reroll.
• There's Options and More Options are pointless for the most part, though can potentially be combined with Moving Box to gain double pickups.
• Humbling Bundle and Bogo Bombs may sound good for Tainted Cain in theory, but in practice these will make it much harder to craft items precisely. Double pickups will yield 2 of the associated crafting ingredient, which can lead to frustrating situations if a recipe specifically calls for 1 of a particular pickup.

Unlockable Items

• 

  Gilded Key - Defeat Isaac, ???, Satan and The Lamb as Tainted Cain.

• 

  Wheel of Fortune - Defeat Ultra Greedier as Tainted Cain.

• 

  Soul of Cain - Defeat Hush and Boss Rush as Tainted Cain.

• 

  Gold Pill - Defeat Mega Satan as Tainted Cain.

• 

  Bag of Crafting - Defeat Delirium as Tainted Cain.

• 

  Lucky Sack - Defeat Mother as Tainted Cain.

• 

  Blue Key - Defeat The Beast as Tainted Cain.

Trivia

• The achievement for unlocking Tainted Cain is "The Hoarder", a possible title for the character.

Birthright effect

Item pedestals drop more pickups.

Bugs

Bug!	In Co-Op mode, if Tainted Cain takes an item from the boss pedestal, he will take every other unclaimed item at once.

Characters
Rebirth Afterbirth Afterbirth † Repentance Tainted