Binding of Isaac: Rebirth Wiki

Added in Repentance

Tainted Apollyon is a character added in The Binding of Isaac: Repentance. He is the alternate version of Apollyon Apollyon. Tainted Apollyon is unlocked by reaching Home Home and using the Red Key Red Key, Cracked Key Cracked Key, or Soul of Cain Soul of Cain to access a special room in one of the walls while playing as Apollyon.

Tainted Apollyon starts with 2 heart containers, Abyss Abyss in the consumable slot, and 1 red Abyss locust familiar that swarms erratically around Apollyon. When Abyss is used, items in current room are destroyed and turned into further locust familiars, some items granting special types of locusts. They charge in the direction Tainted Apollyon is firing until they hit something, dealing Tainted Apollyon's damage per tick.

Unlockable Items[]

Strategy and Items[]

  • The randomness of Apollyon Apollyon's Void Void is substituted for a guaranteed DPS upgrade with Abyss. This allows for easier judgement over whether active or mediocre items should be destroyed.
  • If Tainted Apollyon uses Abyss while picking up an active item, it will be turned into a locust; this is due to the change to items being able to be destroyed while being picked up in Repentance.
    • This does not apply to any other characters, as Tainted Apollyon is the only one who can have Abyss in his consumable slot, and therefore both pick up an active item and use Abyss simultaneously.
    • Be careful if swapping active items while picking up a new one as the old item will also be turned into a locust.
  • In rooms where the player is presented a choice between several items (i.e. Boss Rush Boss Rush, Treasure Room Treasure Rooms on the alternate path, Treasure Room Treasure Rooms/Boss Room Boss Rooms under the effect of More Options More Options/There's Options There's Options, certain Angel Room Angel Room layouts, etc.) using Abyss will only give one locust for each item choice/set.
    • This does not apply to rooms where the player can collect multiple items without penalty such as a Library Library, which can be fully absorbed, making them extremely useful to find.
  • Locusts deal full damage per tick, meaning that it is important to find a balance between the number of locusts spawned and amount of damage dealt. Items from the Boss item pool are usually good sources of damage, so it may be worth it to seek them out immediately.
  • Keep in mind that some Items give special Locusts. However, many of these Items are quite powerful, and may be more valuable if collected than if they are turned into Locusts.
    • Ipecac Ipecac, for example, generates a unique poison locust with increased damage when Abyss consumes it; however, taking the item itself is almost always a superior choice, as the damage bonus from Ipecac affects all locusts Apollyon has, scaling further than the single locust would.
  • Like Void Void, Abyss can be used while holding an item, meaning it is completely possible to buy shop items and consume the item to grant a locust. One-time or low-use items such as Mom's Coin Purse Mom's Coin Purse, Booster Pack Booster Pack, and Voodoo Head Voodoo Head can be great items to do this with.
    • This can also be used with blind item pedestals (such as on the alternate path or with Curse of the Blind), allowing Tainted Apollyon to use Abyss at the last second should he find the collected item to be undesirable.
  • Tainted Apollyon has very low Tears. Items such as The Sad Onion The Sad Onion and Torn Photo Torn Photo, if not absorbed, can be invaluable.
    • While Soy Milk Soy Milk gives a heavy tears upgrade, it will also decrease the damage of your locusts drastically. As such, it may be better to destroy it for a locust.
  • Extension Cord Extension Cord: Every locust will generate a beam of electricity, significantly increasing the range and damage potential of Tainted Apollyon.
  • Genesis Genesis will remove all locusts, and does not replace them with items, making this item a gamble for Tainted Apollyon.
  • Death Certificate Death Certificate (or Metronome Metronome imitating its effect) is even stronger than normal on tainted Apollyon, as he can convert a room full of items to locusts without being transported back to the run; this means he can leave the death certificate area with both an item of his choice an an enormous swarm of permanent locusts, just as long as he uses Abyss Abyss in a room before choosing an item in another room.


  • The Hebrew term Abaddon, and its Greek counterpart Apollyon appear in the Bible as a place of destruction and an archangel of the abyss. The supposed crack on Apollyon's face is a reference to that void that is used to reference the bottomless pit which is Sheol Sheol.
    • In Christianity, Apollyon appears in the Book of Revalations as the Destroyer and King of locusts, with him liberating his plague of locusts on Earth. Apollyon's cracked face referencing the events in the Apocalypse.
    • XVI - The Tower XVI - The Tower and XVI - The Tower? XVI - The Tower? propose a cycle of desired creation and destruction. The events in the apocalypse marking the end of the cycle to a new perfect era.
  • The crack on Apollyon's face could also be a reference to Azami Kurotani from the manga Uzumaki by Junji Ito, who has a very similar crack on her face.
  • The achievement for unlocking Tainted Apollyon is "The Empty", a possible title for the character.



Bug Bug! When using Esau Jr. Esau Jr., all Red Locusts are permanently lost, even after switching back.