Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Repentance

Sulfur is an activated item added in The Binding of Isaac: Repentance.


  • Upon activation, Isaac is turned into a demon and gains the effects of Brimstone Brimstone for the current room.
    • If Sulfur has already been used in the current room, it instead gives Isaac +1.8 damage for the current room and increases the size of the laser.
      • Further uses of Sulfur will continue increasing Isaac's damage.
  • This item belongs to the Leviathan set. Collecting three items from this set will transform Isaac into Leviathan.


  • Sulfur functions identically to Brimstone. For a full list of interactions, see that page.


  • 4.5 Volt 4.5 Volt: Allows for repeated usage of Sulfur in one room.
  • Brimstone Brimstone/Car Battery Car Battery: Activates twice to give an additional damage bonus and wider laser.

In-game footage[]


  • "Sulfur" and "Brimstone" were once synonyms but the word "brimstone" has fallen out of use (outside of biblical usage).
  • Originally in Antibirth, due to a bug, using Sulfur twice in one room would permanently grant Brimstone to Isaac.