Binding of Isaac: Rebirth Wiki

Starter Deck is a passive item.


  • Allows Isaac to carry two cards or runes at once. Cycle through cards by pressing the Control key (PC), R2 (PlayStation), RT (Xbox), or ZR (Switch, 3DS).
  • Replaces all pills with cards. Pills already on the ground will be converted to cards or runes upon picking up Starter Deck.
  • Spawns a random card.


  • When picking up Starter Deck in a shop that has a pill for purchase, the pill can still be purchased and used. If the pill is dropped, it will be turned into a card.
  • Picking up 2 Starter Decks won't allow you to carry 3 cards at once.


  • Added in Afterbirth †Acid Baby Acid Baby: Spawns cards or runes instead of pills. Using cards or runes will not trigger the room-wide poisoning effect.
  • Removed in Repentance Caffeine Pill Caffeine Pill: A pill drops normally, but if it is picked up and dropped, or left on the ground while visiting other rooms, it becomes a card.
  • Little Baggy Little Baggy: Overrides the effect of Little Baggy (switch from receiving only pills to only cards).
    • Added in Repentance Having both items allow both cards and pills to appear again.
    • Picking up Little Baggy while already holding Starter Deck will turn any held cards or runes into pills for one time.
  • Mom's Bottle of Pills Mom's Bottle of Pills: Gives a card instead of a pill, essentially becoming equivalent to a Deck of Cards Deck of Cards.
  • Added in RepentanceXIV - Temperance? XIV - Temperance?: Forces Isaac to eat pills even with Starter Deck.

In-game Footage[]


  • The Starter Deck will paint a five-color pentagram on Isaac's head, which is a reference to the Magic: The Gathering logo.
  • This item is used in It's in the Cards (challenge #14).
  • Added in Repentance Starter Deck also appears in Cantripped! (challenge #43) with a unique function of increasing the number of item cards that Tainted Cain Tainted Cain can carry at once. It replaces all Boss Room Boss Room items in this challenge.