Binding of Isaac: Rebirth Wiki

Spider Bite is a passive item.


  • Adds a 25% chance to shoot slowing tears, reducing the speed of enemy movement and any projectile fired by them.
  • Added in Afterbirth † This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.


  • The slow duration is 2.5 seconds.
  • The slow effect chance depends on the luck stat. The activation rate is equal to 1/(4 - (Luck / 5)). At base luck (0), the chance is 25%, maxing out at 100% at 15 luck.
    • Due to how this formula works, increases in activation rate are only seen with every 5 points of luck, as this formula rounds down after dividing Isaac's luck by 5.


In-game Footage[]


PC C7QT SGJC (Treasure Room adjacent to spawn)

PS4 BW8B CH33 (Treasure Room adjacent to spawn)

Vita F20M 8X2T (Treasure Room adjacent to spawn)

3DS 0YPD YZ06 (First floor Treasure Room; Curse of the Blind)

Switch Greedier mode only GFVY BA4M (First Golden Treasure Room)