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Cards and Runes
Cards and runes are usable items with a wide variety of effects. They take up the same slot as Pills. Runes and special cards are unlocked by completing challenges. -
Binding of Isaac: Rebirth Wiki
The Binding of Isaac: Rebirth is a randomly generated action RPG shooter with heavy roguelike elements. Players will accompany Isaac on a quest to escape his mother, facing off against droves of mysterious creatures, discovering -
Items
Items are an integral part of the game-play of The Binding of Isaac: Rebirth. They modify Isaac's attributes, grant or modify tear effects, and much more. Items are classified into several distinct types -
Characters
This article is about the main player character. For the additional multiplayer characters, see Babies. For non-player characters, see NPCs. There are 34 playable characters in The Binding of Isaac: Rebirth, with 11 available -
Dice Room
In addition to whatever else the room holds, there will always be a symbol of one of the sides of a die in the 5x5 center of the room. The amount of pips shown will -
Completion Marks
Completion marks are earned by completing specific objectives in The Binding of Isaac: Rebirth. As you complete these objectives, the post-it note on the character select screen fills up with Completion Marks. If objectives -
The Lost
The Lost is a secret character. 3DS The Lost also starts with D4 (if unlocked). -
Devil Room (Item Pool)
This article is about the item pool. For the room, see Devil Room. The Devil Room pool is the pool of items that can be found in the Devil Room. All items can be bought -
Challenges
Challenges are unique runs in the game. Isaac typically starts each challenge with one or more specific items which makes normal play more difficult. With few exceptions, Treasure Rooms are not available during challenges. Each -
Achievements
For tips and strategies on completing achievements, see achievement tips. Achievements are unlocked after completing Challenges, reaching certain milestones, achieving hidden goals, or unlocking certain items. In the PC version, every Steam achievement exactly corresponds -
Birthright
Birthright is an unlockable passive item added in The Binding of Isaac: Repentance. Effects[] Grants a passive ability that varies from character to character. The effect typically enhances/magnifies the character's special traits or -
Angel Room (Item Pool)
This article is about the item pool. For the room, see Angel Room. Items in this pool can be found in the Angel Room. -
Pills
Pills are pickups that can provide useful or inhibiting effects. They take up the same slot as cards and runes. At the start of each run, an effect is randomly assigned to each color of -
The Forgotten
Stats Starting Items -
Keeper
This article is about the playable character. For the monster, see Keeper (Enemy). Keeper is a secret character added in The Binding of Isaac: Afterbirth. -
Mother
This article is about the final boss of Corpse. For the boss of chapter 3 and chapter 3.5, see Mom. Mother is a boss added in The Binding of Isaac: Repentance and the only -
Machines
Machines are objects that Isaac can interact with to gain a variety of rewards. Walking up to the Slot Machine and bumping into it will consume one penny and spin the slots. The Machine then -
C Section
C Section is an unlockable passive item added in The Binding of Isaac: Repentance. C Section has a variety of sprite sheets for its fetus shots, depending on which character is using it: -
Jacob & Esau
Stats Starting Items -
Sacrifice Room
Sacrifice Rooms are special rooms that contain a set of spikes in their center. Isaac can damage himself on the spikes for a chance to spawn a Chest or a Locked Chest. The chance is -
Trinkets
Trinkets are a kind of collectible with their designated slot that provide passive bonuses. Only one trinket can be carried at a time and must be dropped if you wish to carry another. Some of -
Tainted Lost
Tainted Lost is a character added in The Binding of Isaac: Repentance. It is the alternate version of The Lost. Tainted Lost is unlocked by reaching Home and using the Red Key, Cracked Key, or -
The Beast
The Beast is a boss added in The Binding of Isaac: Repentance DLC. She appears in Home and is the final boss of Ending 22 and The Binding of Isaac as a whole. After defeating -
Debug Console
The debug console is accessible in The Binding of Isaac: Afterbirth †and The Binding of Isaac: Repentance. It is an extremely useful way to verify a particular game mechanic, explore a seed, test launch options -
Greed Donation Machine
The Greed Donation Machine appears after every Ultra Greed fight in Greed mode or Greedier mode. Upon touching the Greed Donation Machine, Isaac will donate a coin, causing the displayed coin total to increment. Similar
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