Binding of Isaac: Rebirth Wiki

Skatole is a passive item.

Effects[ | ]

  • This item belongs to the BeelzebubBeelzebub set. Collecting three items from this set will transform Isaac into a giant humanoid fly.
  • (in Repentance) This item belongs to the Oh CrapOh Crap set. Collecting three items from this set will transform Isaac into a walking pile of poop.

Notes[ | ]

  • This item can only be naturally obtained from the Shell GameShell Game.
    • (in Repentance) Skatole exists in an otherwise unused shellGame item pool. This means it can also be acquired with Collectible Chaos iconChaos and bosses in The VoidThe Void can drop it.
  • BeelzebubBeelzebub's effect overrides Skatole.
  • (except in Repentance) Flies spawned by Boss The Husk ingameThe Husk will not become passive.
  • (in Repentance) Due to being quality 0, Skatole cannot be obtained from Shell GameShell Games after Collectible Sacred Orb iconSacred Orb has been picked up.
  • This item makes Boss The Duke of Flies ingameThe Duke of Flies a lot easier, as most of his attacks, which spawn flies, will instantly be converted. Staying out of his way while having Skatole can even make it so he ends up killing himself.

In-game footage[ | ]

Trivia[ | ]

  • Skatole is a mildly toxic white crystalline organic compound that occurs naturally in feces.
  • According to Edmund McMillen's First post-Repentance Lore Stream, Skatole's visual was designed first, with McMillen then working backwards to create an appropriate effect to justify an item that puts a poop on Isaac's head.
  • Skatole was considered as a cosmetic hat for Team Fortress 2, alongside tears, Collectible Brimstone iconBrimstone, and Collectible Tiny Planet iconTiny Planet. It was dropped as Valve "... didn't want players running around with a wet piece of poop on their heads."
  • (in Repentance) This item is used in Scat Man (challenge #36).
  • (in Repentance) This item is one of the only five that count towards 2 transformations, the other four being Collectible Hive Mind iconHive Mind, Collectible The Bible iconThe Bible, Collectible Magic Mushroom iconMagic Mushroom and Collectible Parasitoid iconParasitoid.

Bugs[ | ]

Bug Bug! (except in Repentance) Skatole's slowdown effect also affects TumorTumors and its variants, despite them not being flies.