Sissy Longlegs is a passive item.
Effect
- Spawns a familiar that wanders around the room and occasionally spawns friendly Blue Spiders.
- She can only spawn up to 5 Blue Spiders at a time.
- She only spawns Blue Spiders when there are enemies in the room.
Charms enemies briefly on contact.- This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.
Charms enemies briefly on contact.Synergies
- Hive Mind: The Spiders she spawns deal double damage.
Interactions
- BFFS!: No effect.
In-game Footage
Gallery
Sissy Longlegs model as she appears in-game.
Seeds
PC 
XLEO NTXG (Treasure room adjacent to spawn)
PC KGEW HH4V (Treasure room adjacent to spawn)
PC AQWH LK4Z (Treasure room adjacent to spawn)
PC 
8XCD EP28 (Treasure room adjacent to spawn)
PC 3ZC9 3HEP (Treasure room adjacent to spawn)
PC 202T V7A2 (Treasure room adjacent to spawn)
PC FWMK PAN4 (Treasure room adjacent to spawn)
PC ARC6 LNWM (First floor treasure room)
PS4 ZFOL XFAB (Treasure room adjacent to spawn)
3DS H0CH AEPS (First floor treasure room)
Switch 8PJR DESD (First floor treasure room)
 Spider Items
|
|---|
| Items |
 The Binding of Isaac: Rebirth
|
|---|
