Sissy Longlegs is a passive item.
Effect[ | ]
- Spawns a familiar that wanders around the room and occasionally spawns friendly Blue Spiders.
- She can only spawn up to 5 Blue Spiders at a time.
- She only spawns Blue Spiders when there are enemies in the room.
Charms enemies briefly on contact.- This item belongs to the Spider Baby set. Collecting three items from this set will transform Isaac into a humanoid spider.
Synergies[ | ]
- Hive Mind: Familiar is bigger. The Spiders she spawns deal double damage.
Interactions[ | ]
- BFFS!: No effect, but familiar is bigger.
In-game Footage[ | ]
Gallery[ | ]
Sissy Longlegs' sprite as she appears in-game.
 Spider Items
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| Items |
 The Binding of Isaac: Rebirth
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