Binding of Isaac: Rebirth Wiki
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(in Afterbirth † and Repentance)

Sinus Infection is a passive item added in The Binding of Isaac: Afterbirth †.

Effects[ | ]

  • Adds a 20% chance to fire a booger tear that stick to the first enemy that they come in contact with and deals damage over time.
    • Each booger deals damage equal to Isaac's tear damage every second.
    • (except in Repentance)The booger lasts for 60 seconds or until the enemy dies.
      • (in Repentance)The booger lasts 10 seconds.

Notes[ | ]

  • Boogers tears cannot pierce through enemies.
  • Multiple boogers can stick to one enemy to deal extra damage.
  • Booger tears pass through fireplaces and bombs even without piercing shots.
  • Boogers cannot inflict status effects, even if the booger's appearance changes.
  • The booger falls off the enemy after they die. If it hits another enemy before it touches the ground, it will stick to them and deal damage.
  • Sinus Infection is extremely effective against bosses. If each booger tear lasts for the full 10 seconds, this item effectively triples Isaac's DPS against bosses.
  • Jumping enemies or bosses like Boss Monstro ingameMonstro and LeaperLeapers and burrowing enemies like Round WormRound Worms and LumpLumps can get rid of the booger when they leap or burrow.
    • Bosses like The Harbingers or Boss Dark One ingameDark One, or enemies like OobOob that have dash attacks do not lose the booger when they go off-screen.
  • The tear-sticking effect is similar to Collectible Explosivo iconExplosivo and (in Repentance)Collectible Mucormycosis iconMucormycosis's.
  • The Nose GoblinNose Goblin trinket's effect is almost identical to Sinus Infection, with an added homing bonus but half the activation chance.
    • When Isaac is holding both Nose Goblin and Sinus Infection each booger tear created by the item has a 50% chance to also have homing.
  • Not affected by Luck.

Synergies[ | ]

  • (in Repentance)Collectible Brimstone iconBrimstone/Collectible The Ludovico Technique iconThe Ludovico Technique/Collectible Tech X iconTech X/Collectible Trisagion iconTrisagion: Every tick of damage Isaac’s tears deal have a chance to attach a separate booger tear on a hit enemy.
  • Collectible Cricket's Body iconCricket's Body: Booger tears will split into split booger tears that can attach to enemies.
  • Collectible Explosivo iconExplosivo: Explosivo tears can also be booger tears which damage the enemy over time while stuck to them before exploding.
  • Collectible Godhead iconGodhead: Shots retain their aura while stuck to an enemy, but the aura can damage only enemies other than the booger victim. If the enemy dies before the booger’s maximum duration, it will resume homing and will often stick to a second enemy.
  • GuppyGuppy: Damage instances from boogers attached to enemies have a 100% ((in Repentance) 50%) chance to spawn a Blue Fly.
  • (except in Repentance)Collectible Lachryphagy iconLachryphagy: All tears have a chance to burst into boogers. Boogers will always burst into more boogers, though some of the boogers may incorrectly appear to be normal tears. When a booger sticks to an enemy, it will burst into 8 boogers which have a high chance of sticking again to the same enemy.
  • Collectible Lost Contact iconLost Contact: Boogers that stick to enemies will block shots, and will not be destroyed in the process.
  • Collectible Polyphemus iconPolyphemus: Booger shots lose the Polyphemus pierce effect, but stick to enemies while dealing the full damage of the Polyphemus shot. Damage does not degrade.
  • (in Repentance)Collectible Spirit Sword iconSpirit Sword: Swings and projectiles have a chance to apply boogers on enemies.
  • Collectible Strange Attractor iconStrange Attractor: Attraction effect will remain on the booger shot stuck to an enemy. This can drag the enemy across the whole room until they reach one wall and get stuck on it, effectively disabling their normal movement.
  • (in Repentance) Collectible Tech.5 iconTech.5: The laser also has a chance to apply boogers on enemies.
  • (in Repentance) Collectible Technology iconTechnology: Hit enemies have a chance for a booger to be applied to them.
  • (in Repentance) Collectible Technology 2 iconTechnology 2: The laser can also apply boogers with the laser’s chance to apply boogers being determined rapidly every tick.
  • Collectible Technology Zero iconTechnology Zero: Boogers can be connected with electricity while being attached dealing large amounts of damage to the booger victim.

Interactions[ | ]

In-game Footage[ | ]


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