Binding of Isaac: Rebirth Wiki

The 12 Signs of the Zodiac are featured as passive collectibles each with effects loosely based on their given namesake.

(except in Rebirth)Collectible Zodiac iconZodiac Grants the effect of a random Zodiac sign each floor.

(in Repentance) Collecting any three items with the stars item tag unlocks the PlanetariumPlanetarium.

Items[ | ]

Name ID Icon Quote Description (in Repentance) Quality
Aquarius 5.100.308 Aquarius Trail of tears A trail of blue creep is left behind Isaac, which damages enemies. (in Repentance) The creep inherits most of Isaac's tear effects, like homing, etc. 2
Aries 5.100.300 Aries Ramming speed +0.25 Speed. Running into enemies while at a high speed will deal damage. (in Repentance) Prevents Isaac from taking contact damage while moving at high speed. 2
Cancer 5.100.301 Cancer HP up + you feel protected Adds 3 Soul HeartSoul Hearts. Grants Collectible The Wafer iconThe Wafer effect for the current room after taking damage. 3
Capricorn 5.100.307 Capricorn All stats up (except in Repentance) Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +1.5 Range, and -1.0 Tear Delay, and gives 1 BombBomb, PennyPenny, and KeyKey.
(in Repentance) Adds 1 Red Heart Container, gives +0.5 Damage, +0.1 Speed, +0.75 Range, and +0.5 Fire Rate, and gives 1 BombBomb, PennyPenny, and KeyKey.
Gemini 5.100.318 Gemini Conjoined friend Spawns a conjoined familiar which chases enemies close to Isaac, dealing ~6.43 damage per second. 1
Leo 5.100.302 Leo Stompy Isaac can destroy rocks by walking into them. 1
Libra 5.100.304 Libra You feel balanced Gives 6 PennyCoins, 6 BombBombs, and 6 KeyKeys and balances out all attributes. 1
Pisces 5.100.309 Pisces Tears up + knock-back shots (except in Repentance) -1 Tear Delay, adds knock-back shots and increases tear size.
(in Repentance) +0.5 Fire Rate, adds knock-back shots and increases tear size.
Sagittarius 5.100.306 Sagittarius Piercing shots + speed up Increases speed by +0.2 and grants piercing tears. 3
Scorpio 5.100.305 Scorpio Poison tears Grants poison tears, which deal damage over time when inflicted. 3
Taurus 5.100.299 Taurus Speed down + rage is building -0.3 Speed. Isaac builds speed while in a room with enemies. At max speed, he gains the Collectible My Little Unicorn iconMy Little Unicorn effect for 5 seconds. 1
Virgo 5.100.303 Virgo You feel refreshed and protected Adds a chance to give a shield that nullifies all incoming damage for 10 seconds upon taking damage. Also converts bad pills into good pills. 2
(except in Rebirth) Zodiac 5.100.392 Zodiac The heavens will change you Gives Isaac a random zodiac item effect that changes every floor. 1

Unlockable Achievements[ | ]

Trivia[ | ]

  • Some of the effects caused by the items in-game are directly related to their astrological significance or symbol. For example, Aquarius is portrayed as a man (Ganymede) bearing water, and in game the item causes Isaac to leave a trail of tears behind him while walking; Libra, which represents weighing scales, balances Isaac's stats.