Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Afterbirth †

Shard of Glass is a passive item added in The Binding of Isaac: Afterbirth †.


  • Adds a 25% chance to drop a full Red Heart upon taking damage.
  • Removed in Repentance Adds a separate 10% chance to gain the Anemic Anemic effect (+5 range, red creep trail) for the current room upon taking damage.
  • Added in Repentance Taking damage will cause Isaac to bleed, spewing red tears around him constantly.
    • Holding a direction of fire focuses the bleeding tears to that direction, with slightly increased range.
    • After bleeding for 20 seconds, Isaac's Red Hearts or Rotten Hearts will take damage (bypassing other Hearts); this is indicated by Isaac slowly turning red after and eventually blinking. This damage also has a 25% chance to drop a full Red Heart. The damaging effect will continue to occur every 20 seconds until the bleeding effect ends.
    • The bleeding effect ends when Isaac receives any form of Red Heart or Rotten Heart healing, if he has no more Red or Rotten Hearts, or if the next hit would kill him.
    • If Isaac has no Red or Rotten Hearts, the bleeding effect of Shard of Glass will not activate.
    • The bleeding effect carries over to the next floor if Isaac moves on to the next floor while still bleeding.


  • Red Hearts spawned by this item may become different hearts in certain Super Secret Rooms.
  • Playing as Keeper Keeper or Tainted Keeper Tainted Keeper will cause the hearts spawned to turn to Blue Flies immediately.
  • Added in Repentance If Shard of Glass is rerolled while Isaac is bleeding, the bleeding will continue, but Red Hearts will no longer spawn when Isaac takes damage. This makes Shard of Glass especially deadly to Tainted Eden Tainted Eden.
  • Added in Repentance The Forgotten The Forgotten can end the bleeding by switching to The Soul The Soul.
  • Added in Repentance The bleeding effect works with Keeper Keeper and Tainted Keeper Tainted Keeper. They will bleed and lose a coin heart until only one coin is left. Receiving coins will stop the bleeding effect. Due to Tainted Keeper only having two coin hearts in most circumstances, bleeding will rarely apply to him.
  • Added in Repentance Rotten Hearts will take bleeding damage only when Isaac has no red hearts remaining. Picking up Rotten Hearts will also end the bleeding.
  • Added in Repentance Using a bed to heal Isaac's red hearts will not stop the bleeding.
  • Added in RepentanceTurning into The Lost via the White Fire Place or Soul of the Lost will stop bleeding effect.

In-game Footage[]


  • "Blood and guts" is a term for violence, typically in fiction.
  • Added in Repentanceif the bleeding is the cause of death, Isaac's last will will show a blood donation machine as the cause of death.


Switch Greedier mode only VYEN N8Z4 (First Golden Treasure Room)

PC Normal and hard modes only 8L1F YVFR (First floor Treasure Room)