Binding of Isaac: Rebirth Wiki

Added in Afterbirth

After obtaining 3 holy items listed below (Added in Repentance 3 items with the angel item tag), Isaac will gain 3 Soul Heart Soul Hearts and permanent flight.

Activated Collectibles[]

Name ID Icon Quote Description Added in Repentance Quality
The Bible 5.100.33
The Bible
4 rooms
Temporary flight On use, Isaac gains flight for the current room. Instantly kills Mom Mom, Mom's Heart Mom's Heart, and It Lives It Lives when activated, but kills Isaac when used on Satan Satan. 1

Passive Collectibles[]

Name ID Icon Quote Description Added in Repentance Quality
Dead Dove 5.100.185 Dead Dove Flight + spectral tears Grants spectral tears and flight. 3
Holy Grail 5.100.184 Holy Grail Flight + HP up Grants flight and one Red Heart container. Added in Repentance Heals an additional Red Heart Red Heart 3
Holy Mantle 5.100.313 Holy Mantle Holy shield Grants a shield that negates the first instance of damage taken, once per room. Does not apply to or negate self-damage (Blood Donation Machine.png Blood Donation Machines, etc). 4
Mitre 5.100.173 Mitre Blessing of purity Grants a chance of converting any Red Heart Red Heart pickups into Soul Heart Soul Hearts instead. 3
Rosary 5.100.72 Rosary Tears + faith up Grants 3 Soul Heart Soul Hearts. Causes The Bible The Bible to appear in any item pool. Added in Repentance +0.5 tears. 2
The Halo 5.100.101 The Halo All stats up Grants one full Red Heart container, +0.3 damage, +0.2 tears, +0.25 range, +0.3 speed, and +0.5 tear height. Added in Repentance Heals 1 additional Red Heart Red Heart. 2
Removed in Repentance Guardian Angel 5.100.112 Guardian Angel Extra protection Spawns an orbital familiar that blocks enemy shots, deals 105 damage per second to enemies, and increases the speed of all orbital familiars. 2
Removed in Repentance Sworn Protector 5.100.363 Sworn Protector Protective friend Spawns an orbital familiar which does 105 damage per second and attracts and blocks enemy shots. Upon blocking 10 shots in a room, it drops an Eternal Heart Eternal Heart. 3
Added in Repentance Celtic Cross 5.100.162 Celtic Cross Blessing of protection Grants a chance to trigger the Book of Shadows Book of Shadows effect upon taking damage, creating a shield that nullifies all types of damage for 7 seconds. 1
Added in Repentance Divine Intervention 5.100.568 Divine Intervention Double tap shield Double tapping a fire key creates a shield that pushes away enemies and reflects enemy projectiles and lasers. 2
Added in Repentance Godhead 5.100.331 Godhead God tears Removed in Repentance Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, +0.8 Tear Height, and +1.2 Range.
Added in Repentance Grants homing tears with a damaging halo. +0.5 Damage, -0.3 Tears -0.3 Shot Speed, and +0.8 Tear Height.
Added in Repentance Holy Light 5.100.374 Holy Light Holy death shot Adds a chance to fire holy tears, which will create a damaging light beam in the area if they hit an enemy. 3
Added in Repentance Immaculate Heart 5.100.573 Immaculate Heart Halo of tears Adds one Red Heart Container and fully restores health. x1.2 damage multiplier. Isaac will occasionally fire extra tears that orbit around him. 3
Added in Repentance Revelation 5.100.643 Revelation Awaken your faith Grants flight and two Soul Heart Soul Hearts. In addition to tears, Isaac can charge up and fire a powerful holy laser. 4
Added in Repentance Sacred Heart 5.100.182 Sacred Heart Homing shots + DMG up Removed in Repentance Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, -0.25 Shot Speed, and +4.125 Range.
Added in Repentance Adds a Red Heart Container. Grants homing tears, a x2.3 Damage multiplier, +1 flat Damage, -0.4 Tears, and -0.25 Shot Speed.
Added in Repentance Sacred Orb 5.100.691 Sacred Orb Destined for greatness Prevents items of quality 0-1 from appearing, and items of quality 2 from appearing 33% of the time, greatly increasing the quality of items received from all item pools. Quest items are unaffected. 4
Added in Repentance Salvation 5.100.696 Salvation Divine protection Gives Isaac a halo that summons beams of light on enemies inside it. The halo grows larger the more times Isaac has taken damage this floor. 3
Added in Repentance Scapular 5.100.142 Scapular Pray for a miracle Once per room, when Isaac is reduced to his last half heart, he is granted one Soul Heart Soul Heart. 2


  • Despite having the same name, the familiar Seraphim Seraphim does not contribute to the Seraphim transformation.
  • Picking up and dropping multiple, distinct copies of The Bible The Bible will count each copy towards the transformation. This makes Rosary Rosary and to a lesser degree, Rosary Bead Rosary Bead especially helpful in gaining the transformation.


PC Normal mode only QYTQ 9MY6 First two floors

PC Hard mode only 6NKO NW3F (Cellar II boss. Needs to have Guppy's Tail from Curse room on 1st floor to get red chest. Rosary in Treasure room on 1st floor, The Bible from red chest on 2nd floor, The Halo from 2nd boss.)

PC Hard mode onlyG3L6 38DF (1st Floor Seraphim - Must be playing a character who can receive soul hearts - Head up to get scapular - reduce to one and a half soul hearts or half a red heart and a soul heart - play sacrifice room to the south east of the start room by entering, stepping on the spikes, exiting, and repeating, for Holy Light from Angel Room and Immaculate Heart from sacrifice room pedestal [still needs testing from a user with Dead God unlocked])