Secret Room (Item Pool)

Item Pool
Normal/Hard	Treasure Room	Shop	Library	Curse Room	Boss	Secret Room	Devil Room	Angel Room	Golden Chest	Red Chest	Beggar
	Devil Beggar	Key Master	Bomb Bum	Planetarium	Crane Game	Rotten Beggar	Battery Bum	Old Chest	Wooden Chest	Mom's Chest	Baby Shop
Greed Greedier	Treasure Room	Shop	Library	Curse Room	Boss	Secret Room	Devil Room	Angel Room	Golden Chest

Items in this pool can be found in the Secret Room.

Activated Collectibles

Name	ID	Icon	Weight	Description
Blank Card	5.100.286		1	Has the same effect as the card or rune currently held by Isaac. Has the same effect as the card currently held by Isaac.
Book of Secrets	5.100.287		1	Gives the effect of Treasure Map, The Compass, or Blue Map for the duration of the current floor.
Forget Me Now	5.100.127		1	On use, re-generates the current floor with a new layout. Isaac loses Forget Me Now, but keeps other items and consumables picked up on the original floor.
The Necronomicon	5.100.35		1	Deals 40 damage to every enemy in the room.
We Need to Go Deeper!	5.100.84		1	Creates a trapdoor to go to the next floor.
Compost	5.100.480		1	Doubles Isaac's Blue Flies and Blue Spiders, or spawns one if Isaac has none. Converts pickups in the current room into Blue Flies or Blue Spiders.
Clear Rune	5.100.263		1	Has the same effect as the rune or soul stone currently held by Isaac.
Death Certificate	5.100.628		1	Takes Isaac to an abandoned and expanded version of Home, which has one copy of every item in the game. After taking an item, Isaac returns to the room he used Death Certificate in.
D Infinity	5.100.489		1	Grants a random dice item that changes each use. Acts as any dice item, and can by cycled by pressing the drop key.
Esau Jr.	5.100.703		1	Swaps between the current character and Esau Jr., who has +2 flat damage and flight. Characters have independent items and health. Dying as either character ends the run.
Eternal D6	5.100.609		1	Rerolls all items in the room. Each item has a chance to disappear instead.
Keeper's Box	5.100.719		1	Spawns a random shop item or pickup which can be bought for its normal price.
Mega Mush	5.100.625		1	Gigantifies Isaac for 30 seconds, increasing damage and range while lowering tears, granting invulnerability, and allowing Isaac to crush enemies and obstacles he walks on. The effect persists between rooms.
Placebo	5.100.348		1	When used, copies the effect of the pill Isaac is currently holding without consuming it. Does not copy the effects of cards or runes.
Red Key	5.100.580		1	Creates a new room adjacent to a viable wall, indicated by the outline of a door. These rooms have a chance to be various special rooms.
R Key	5.100.636		1	Brings Isaac back to the first floor of a new run, retaining all of his items.
Spindown Dice	5.100.723		1	Transforms all items in the room by decreasing their internal ID number.
Wavy Cap	5.100.582		1	Increases tears, decreases speed, and distorts the screen. All effects become more pronounced with repeated use, and wear off by clearing rooms.

Passive Collectibles

Name	ID	Icon	Weight	Description
1up!	5.100.11		1	Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health and lose the 1up!.
Black Lotus	5.100.226		1	Grants one Red Heart, one Soul Heart, and one Black Heart.
Cursed Eye	5.100.316		1	Grants charged tears that can be fired in a tight burst. Getting hit while charging will teleport Isaac to another room.
Infamy	5.100.242		1	Chance to block projectiles coming from any direction.
Lost Contact	5.100.213		1	Isaac's tears can hit and destroy enemy projectiles. -0.16 shot speed.
Missing No.	5.100.258		1	Randomizes all passive items and stats upon pickup and at the start of each succeeding floor.
Missing Page 2	5.100.262		1	Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, deals damage to all enemies in the room. Increases the damage of Black Hearts and The Necronomicon-like effects by 40.
Mystery Sack	5.100.271		1	Spawns a familiar that drops a Heart, coin, bomb, or key every 5-6 rooms.
Odd Mushroom	5.100.121		1	Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear height, and -0.1 speed.
Odd Mushroom	5.100.120		1	+1.7 tears, +0.3 speed, slightly reduces damage.
Pyro	5.100.190		1	Grants 99 bombs.
Raw Liver	5.100.16		1	Grants 2 Red Heart containers and completely restores health.
Samson's Chains	5.100.321		1	Attaches a ball and chain to Isaac that pulls behind him that damages enemies, blocks shots, and destroys most obstacles.
Skeleton Key	5.100.17		1	Gives Isaac 99 keys.
Transcendence	5.100.20		1	Grants flight.
A Quarter	5.100.74		1	Gives Isaac 25 coins.
Bomb Bag	5.100.131		1	Spawns a familiar that drops a bomb every 3 rooms.
Mr. Mega	5.100.106		1	Grants 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage.
Sack of Pennies	5.100.94		1	Spawns a familiar that drops a coin every 2 rooms.
GB Bug	5.100.405		1	Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over. Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits.
Key Bum	5.100.388		1	Spawns a familiar that follows Isaac and collects Keys for himself, giving random Chests in return.
Rune Bag	5.100.389		1	Spawns a familiar that drops a random rune every 5-6 rooms.
Dad's Ring	5.100.546		1	Creates a ring of light around Isaac that petrifies enemies in contact.
Eye of Greed	5.100.450		1	Every 20 tears, Isaac loses 1 coin and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins.
Greed's Gullet	5.100.501		1	Grants a Red Heart container for every 25 coins Isaac has.
Astral Projection	5.100.677		1	Causes Isaac to turn into a ghost if he gets hit while in an uncleared room, giving him flight and spectral tears and blocking the next hit he takes.
Binge Eater	5.100.664		1	+1 red heart container and fully heals Isaac. Item pedestals cycle between their normal items and food, and collecting food grants a temporary damage boost and permanent bonuses to 2 stats.
Chaos	5.100.402		1	Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools.
Cracked Orb	5.100.675		1	Unlocks doors and reveals a random room on the map when Isaac takes damage.
Echo Chamber	5.100.700		1	When Isaac uses a card, pill, or rune, he also uses a copy of every card/pill/rune he used after picking up Echo Chamber.
Epic Fetus	5.100.168		1	Isaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.
Evil Charm	5.100.632		1	Increases luck by 2.0. Provides immunity to burn, confusion, fear, and poison.
Glitched Crown	5.100.689		1	Before being picked up, item pedestals cycle between 5 random items.
Inner Child	5.100.688		1	Upon death, Isaac respawns in the current room with half a heart left, a massive size down, and +0.2 speed.
Isaac's Tomb	5.100.701		1	Spawns an Old Chest at the start of each floor.
Keeper's Kin	5.100.717		1	Rocks and props spawn blue spiders over time while in a room with enemies, and spawn two blue spiders when destroyed.
Keeper's Sack	5.100.716		1	Gives range, speed, or damage when buying things from a shop. Also spawns three coins and a key on pickup.
Lost Soul	5.100.612		1	Gives Isaac a soul familiar that dies in one hit, respawning at the start of the next floor. If it survives an entire floor, it rewards Isaac with hearts or items.
Orphan Socks	5.100.571		1	Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 soul hearts.
Rock Bottom	5.100.562		1	Locks Isaac's attributes to their highest values reached.
Sack Head	5.100.424		1	Coins, bombs, keys, cards, runes and batteries have a chance to become sacks.
Sack of Sacks	5.100.500		1	Spawns a familiar that drops a sack every 5-6 rooms cleared.
Sausage	5.100.669		1	Adds a Red Heart container, and increases speed, damage, tears, range, shot speed, and luck.
Spirit Shackles	5.100.674		1	On death, Isaac's ghost is chained to his dead body and he can continue to fight with 1/2 of a heart, returning to life after 10 seconds. After it activates, it must be recharged by picking up a soul heart.
Strawman	5.100.667		1	Spawns Keeper to fight enemies alongside Isaac. If Keeper dies, he spawns blue spiders and Strawman is removed from Isaac's inventory.
TMTRAINER	5.100.721		1	Causes all future items to be "glitched", granting them completely random effects.
Sacred Orb	5.100.691		0.5	Prevents low-quality items from spawning, greatly increasing the quality of items received from all item pools.
Vanishing Twin	5.100.697		0.5	Spawns a familiar that becomes a clone of the floor's boss when entering the boss room. Defeating it drops an extra item.