Name
|
ID
|
Icon
|
Weight
|
Description
|
1up!
|
5.100.11
|
|
1
|
Gives Isaac an extra life. Upon death, he will respawn in the previous room with full health and lose the 1up!.
|
Black Lotus
|
5.100.226
|
|
1
|
Grants one Red Heart, one Soul Heart, and one Black Heart.
|
Cursed Eye
|
5.100.316
|
|
1
|
Grants charged tears that can be fired in a tight burst of four. Getting hit while charging will teleport Isaac into another room.
|
Infamy
|
5.100.242
|
|
1
|
Chance to block projectiles coming from any direction.
|
Lost Contact
|
5.100.213
|
|
1
|
Isaac's tears can hit and destroy enemy projectiles. -0.16 shot speed.
|
Missing No.
|
5.100.258
|
|
1
|
Randomizes all passive items and stats upon pickup and at the start of each succeeding floor.
|
Missing Page 2
|
5.100.262
|
|
1
|
Grants one Black Heart. Upon taking damage that reduces Isaac's health to one heart or less, activates The Necronomicon effect, dealing 40 damage to all enemies in the room.
|
Mystery Sack
|
5.100.271
|
|
1
|
Spawns a familiar that drops a Heart, coin, bomb, or key every 5-6 rooms.
|
Odd Mushroom
|
5.100.121
|
|
1
|
Grants one empty Heart container, +0.3 damage, +0.25 range, +0.5 tear height, and -0.1 speed.
|
Odd Mushroom
|
5.100.120
|
|
1
|
+1.7 tears, +0.3 speed, slightly reduces damage.
|
Pyro
|
5.100.190
|
|
1
|
Grants 99 bombs.
|
Raw Liver
|
5.100.16
|
|
1
|
Grants 2 Red Heart containers and completely restores health.
|
Sack of Pennies
|
5.100.94
|
|
1
|
Spawns a familiar that drops a coin every 2 rooms.
|
Samson's Chains
|
5.100.321
|
|
1
|
Attaches a ball and chain to Isaac that pulls behind him that damages enemies, blocks shots, and destroys most obstacles.
|
Skeleton Key
|
5.100.17
|
|
1
|
Gives Isaac 99 keys.
|
Transcendence
|
5.100.20
|
|
1
|
Grants flight.
|
A Quarter
|
5.100.74
|
|
1
|
Adds 25 to Isaac's coin count, capping at 99.
|
Bomb Bag
|
5.100.131
|
|
1
|
Spawns a familiar that drops a bomb every 3 rooms.
|
Mr. Mega
|
5.100.106
|
|
1
|
Grants 5 bombs, and makes all dropped bombs larger, which have an increased blast radius and increased damage.
|
GB Bug
|
5.100.405
|
|
1
|
Spawns a familiar that bounces diagonally around the room, applying a random status effect to enemies it hits and has a chance to re-roll pickups it passes over.
Spawns a familiar that follows Isaac. Double tapping the fire button launches it forward, causing it to reroll the first monster or pickup it hits. It respawns after clearing a room.
|
Key Bum
|
5.100.388
|
|
1
|
Spawns a familiar that follows Isaac and collects Keys for himself, giving random Chests in return.
|
Rune Bag
|
5.100.389
|
|
1
|
Spawns a familiar that drops a random rune every 5-6 rooms.
|
Dad's Ring
|
5.100.546
|
|
1
|
Creates a ring of light around Isaac that petrifies enemies in contact.
|
Eye of Greed
|
5.100.450
|
|
1
|
Every 20 tears, Isaac loses 1 coin and shoots an additional gold tear that petrifies enemies and turns them into gold. Any enemy killed while in this state will drop coins.
|
Greed's Gullet
|
5.100.501
|
|
1
|
Grants a Red Heart container for every 25 coins Isaac has.
|
Astral Projection
|
5.100.677
|
|
1
|
Causes Isaac to turn into a ghost if he gets hit while in a room with enemies, giving him flight and spectral tears and blocking the next hit he takes.
|
Binge Eater
|
5.100.664
|
|
1
|
+1 red heart container and fully heals Isaac. Item pedestals cycle between their normal items and food, and collecting food grants a temporary damage boost and permanent bonuses to 2 stats.
|
Chaos
|
5.100.402
|
|
1
|
Drops 1-6 random pickups on the floor. Causes items to be chosen from random item pools.
|
Cracked Orb
|
5.100.675
|
|
1
|
Unlocks doors and reveals a random room on the map when Isaac takes damage.
|
Echo Chamber
|
5.100.700
|
|
1
|
When Isaac uses a card, pill, or rune, he also uses a copy of every card/pill/rune he used after picking up Echo Chamber.
|
Epic Fetus
|
5.100.168
|
|
1
|
Isaac's tears are replaced with guided missiles, like those used by the Doctor's Remote.
|
Evil Charm
|
5.100.632
|
|
1
|
Increases luck by 2.0.
|
Glitched Crown
|
5.100.689
|
|
1
|
Before being picked up, item pedestals cycle between 5 random items.
|
Inner Child
|
5.100.688
|
|
1
|
Upon death, Isaac respawns in the current room with half a heart left, a massive size down, and +0.2 speed.
|
Isaac's Tomb
|
5.100.701
|
|
1
|
Spawns an Old Chest at the start of each floor.
|
Keeper's Kin
|
5.100.717
|
|
1
|
Rocks and props spawn spiders over time while in a room with enemies, and spawn two blue spiders when destroyed.
|
Keeper's Sack
|
5.100.716
|
|
1
|
Gives range, speed, or damage when buying things from a shop. Also spawns three coins and a key on pickup.
|
Lost Soul
|
5.100.612
|
|
1
|
Gives Isaac a soul familiar that dies in one hit, respawning at the start of the next floor. If it survives an entire floor, it rewards Isaac with hearts or items.
|
Orphan Socks
|
5.100.571
|
|
1
|
Prevents creep and floor spikes from damaging Isaac. Also gives Isaac +0.3 speed and 2 soul hearts.
|
Rock Bottom
|
5.100.562
|
|
1
|
Sets all stats to their base value. Prevents stats from being lowered for the rest of the run.
|
Sack Head
|
5.100.424
|
|
1
|
Coins, bombs, keys, cards, runes and batteries have a chance to become sacks.
|
Sack of Sacks
|
5.100.500
|
|
1
|
Spawns a familiar that drops a sack every 5-6 rooms cleared.
|
Sacred Orb
|
5.100.691
|
|
1
|
Prevents low-quality items from spawning, greatly increasing the quality of items received from all items pools.
|
Sausage
|
5.100.669
|
|
1
|
Adds a Red Heart container, and increases speed, damage, tears, range, shot speed, and luck.
|
Spirit Shackles
|
5.100.674
|
|
1
|
On death, Isaac's ghost is chained to his dead body and he can continue to fight with 1/2 of a heart, returning to life after 10 seconds. Must be recharged by picking up a soul heart.
|
Strawman
|
5.100.667
|
|
1
|
Spawns Keeper to fight enemies alongside Isaac. If Keeper dies, he spawns blue spiders and Strawman is removed from Isaac's inventory.
|
TMTRAINER
|
5.100.721
|
|
1
|
Causes all future items to be "glitched", granting them completely random effects.
|
Vanishing Twin
|
5.100.697
|
|
1
|
Spawns a familiar that becomes a clone of the floor's boss when entering the boss room. Defeating it drops an extra item.
|