Binding of Isaac: Rebirth Wiki

(in Repentance)

Sanguine Bond is an unlockable passive item added in The Binding of Isaac: Repentance.

Effects[ | ]

  • Spawns a special set of spikes in the Devil RoomDevil Room. They deal 1 full heart of damage per use.
  • Taking damage from the spikes has a chance to grant a reward.

Rewards[ | ]

Chance Reward
35% Nothing
33% + 0.5 damage
15% 6 pennies
10% 2 Black HeartBlack Hearts
5% A random Devil Room item
2% Transform into LeviathanLeviathan

Notes[ | ]

  • The spikes will appear in the current Devil RoomDevil Room upon picking up Sanguine Bond.
  • The spikes will deal damage to enemies that walk or fly over them, including Boss Krampus ingameKrampus.
    • As Krampus often spawns in the center of the room, it will deal a significant amount of damage to him, almost killing him completely.
  • The item causes all other spikes in the Devil RoomDevil Room to retract.

Synergies[ | ]

  • Collectible Goat Head iconGoat Head: Allows Isaac to enter and leave the Devil Room at will, making this item substantially more powerful, as red hearts can be collected throughout the floor.
    • Collectible Goat Head iconGoat Head + Collectible Scapular iconScapular: The spikes generated by Sanguine Bond can be farmed infinitely.
      • Quitting and reloading the game will also reset the soul heart regeneration provided by Collectible Scapular iconScapular, thus negating the need for Collectible Goat Head iconGoat Head.
  • Character Keeper iconKeeper / Character Tainted Keeper iconTainted Keeper / Collectible Strawman iconStrawman: The pennies that are spawned when stepping on the spikes can be used to heal Keeper and infinitely farm rewards.
  • Collectible Placenta iconPlacenta: With a lot of time, the spikes can be farmed infinitely.
  • Collectible Portable Slot iconPortable Slot: The pennies that are spawned can be gambled to give hearts, allowing more uses.
  • Collectible The Wafer iconThe Wafer / Percs: Hearts will last twice as long, allowing more uses. Further uses may be obtained by sacrificing the black hearts given, and any hearts added from devil room items.

Interactions[ | ]

  • CallusCallus: Will not prevent the damage from spikes created by Sanguine Bond.

In-game footage[ | ]

Trivia[ | ]