Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in RepentanceSacrifice Room door.png

Sacrifice Rooms are special rooms that contain a set of spikes in their center. Removed in Afterbirth Isaac can damage himself on the spikes for a chance to spawn a Chest or a Golden Chest. The chance is determined by the seed, meaning Isaac must damage himself on the spikes a set number of times for a Chest to spawn. Added in Afterbirth Sacrifice Rooms were reworked, with a wide variety of possible rewards (shown below).

The base chance of a Sacrifice Room being generated is 1/7 (~14%). If Isaac's total heath is equal to or greater than his total red heart containers, an additional 1/4 chance applies for a total of 5/14 (~36%).

Sacrifice Rooms are mutually exclusive with Dice Rooms. If a Sacrifice Room is to be generated, it has a 1/50 base chance to be replaced by a Dice Room, plus an additional 1/5 chance for a total of 27/125 (~22%) if Isaac has 2 or more keys.

Rewards Added in Afterbirth[]

The payouts only depend on the number of sacrifices made. The number of sacrifices is reset to 0 when Isaac goes to the next floor.

№ of sacrifices on Current Floor Chance Reward
1st / 2nd 50% Nothing
50% 1 Penny
100% Added in Afterbirth † 1 Bomb (Only if the first floor boss has been defeated in less than one minute and Isaac has no bombs, to help obtain 15►Broken Shovel Broken Shovel)
3rd 33% Nothing
67% "You feel blessed!" (increased chance to receive an Angel Room over a Devil Room for the current floor)
  • Does not increase the chance of a Devil/Angel Room after defeating a boss, only the chance of getting an Angel Room over a Devil Room.
  • Can cause an Angel Room to spawn even if Isaac has already taken a deal with the Devil.
  • Gives a smaller bonus than the "You feel blessed!" effect below.
  • Removed in Repentance A guaranteed Angel Room replacement if this occurred in a Chapter 1 XL floor.
  • Added in Repentance If Isaac has not yet encountered a Devil/Angel Room yet, guarantees the first room encountered to be an Angel Room.
4th 50% Nothing
50% 1 random chest (The type of chest is governed by the same mechanic as room drops. Thus, regular chests are more likely to spawn than any other kind of chest.)
5th 33% 3 Pennies (These coins do not have a chance to spawn as a nickel or a dime.)
67% "You feel blessed!" (Same conditions as 3rd sacrifice but providing a stronger modifier.)
6th 33% Teleport to the Devil/Angel Room. (If the floor's Devil/Angel Room has not been spawned yet, an Angel Room is guaranteed to spawn — even if a Devil Deal has already been taken.)
67% 1 random chest (The type of chest is governed by the same mechanic as room drops. Thus, regular chests are more likely to spawn than any other kind of chest.)
7th 33% 1 random Angel Room item. Added in Repentance if a Deal with the Devil was taken previously, 15►Redemption Redemption will spawn instead if unlocked.
67% 1 Soul Heart
8th 100% 6 Troll Bombs
9th 100% Uriel battle
10th 50% 7 Soul Hearts
50% 30 Pennies
11th 100% Gabriel battle
12th and onwards 50% Nothing
50% Teleport directly to the Dark Room Dark Room.



  • The sacrifice rewards are determined ahead of time, not when Isaac steps on the spikes.
    • Received items/trinkets can be changed, however. If Isaac checks the items and resets (such as with the 15►Glowing Hour Glass Glowing Hour Glass), he can find that item on the same floor, then redo the sacrifice to force a different item to spawn.
    • Resetting will reset Isaac's number of sacrifices to what it was prior to his reset unless stated otherwise.
  • Spikes in a Sacrifice Room will deal damage even when flown over, so Isaac can use them even with Flight.
  • Invincibility and shields will not trigger a sacrifice (including 15►Holy Mantle Holy Mantle).
  • Removed in Repentance The Callus Callus prevents the Sacrifice Room from functioning.
  • Sacrifice Rooms do not naturally appear in the Chest Chest, Dark Room Dark Room, or The Void The Void.
  • Added in Repentance Sacrifice Rooms won't teleport Isaac to the Dark Room Dark Room during a challenge or daily challenge that does not end there, thus nothing will happen from the 12th sacrifice onward.
  • Added in Repentance If more than one Sacrifice Room is created on one floor with 15►Red Key Red Key or equivalent effects, each Sacrifice Room has its own sacrifice counter. For example, doing 3 sacrifices in one room, then 3 in another gives Isaac the 1st to 3rd effects from both rooms, instead of 1st to 3rd, then 4th to 6th. Additionally, performing more sacrifices in the first room again will count up from 4th; the count is not reset by using another room.
  • Added in Repentance Sacrifice Rooms generated by using 15►Red Key Red Key in the Dark Room Dark Room will, when used enough times, teleport Isaac to a new instance of the Dark Room. This effectively generates a new floor.
  • Added in Repentance Entering a Sacrifice Room while holding Flat File Flat File will cause the spikes to be retracted into the ground. Dropping the trinket and re-entering the room will cause the spikes to reappear.
  • Added in Repentance If another non-co-op character takes damage on Sacrifice Room spikes, such as by using Soul of the Forgotten Soul of the Forgotten or Soul of Jacob and Esau Soul of Jacob and Esau, it will spawn 7 troll bombs every time they take damage. This still moves the room's sacrifice counter up for each hit.

Notes on Rebirth Sacrifice Rooms[]

  • Only one chest can be received per Sacrifice Room.
  • Taking damage down to half a red heart will always drop a chest. (Because ??? ??? cannot have Red Heart containers, dropping down to half a heart does not guarantee a drop.)
  • Dying on the spikes guarantees a chest, which can be useful if Isaac is low on health and has more lives from something like 15►Dead Cat Dead Cat.
  • Dying in a Sacrifice Room with the Missing Poster Missing Poster will reveal puzzle pieces used to unlock the The Lost The Lost.

Notes on Afterbirth Sacrifice Rooms[]

  • If Isaac receives both of the "You feel blessed!" effects, they will stack for a 65% Angel Room generation chance.
  • The amount of health Isaac has left after taking a sacrifice does not affect the payout probabilities.
  • Removed in Repentance Losing red hearts due to the spikes will reduce the chance for a Devil Room to appear.
  • Isaac's Luck stat does not affect the payout probabilities.
  • If Uriel or Gabriel spawn, they can be despawned by exiting the room.
  • While Uriel and Gabriel can normally fly over spikes without taking damage, they will take damage from Sacrifice Room spikes.
  • Dying in a Sacrifice Room while holding Missing Poster Missing Poster will unlock The Lost The Lost (except during a Challenge or Victory Lap).
  • 15►The Wafer The Wafer, 15►Cancer Cancer, and the Percs pill reduce the spikes' damage to half a heart, allowing Isaac to make more sacrifices.
  • If using the BASE MENT seed, the Dark Room Dark Room teleport can escape the infinite Basement Basement floors.
  • Even if 15►The Negative The Negative isn't unlocked, Isaac can still teleport to the Dark Room Dark Room.
  • Dying and respawning does not reset the number of sacrifices made, so 15►Dead Cat Dead Cat can be used on low health in an attempt to acquire soul hearts.

Unlockable Achievements[]


Bug Bug! Removed in Repentance Found HUD will incorrectly display Angel Room generation chance at 100% when receiving either of the "You feel blessed!" effects.
Bug Bug! Added in Repentance If Isaac touches a Red Chest, the game will determine whether or not he gets a Devil/Angel Room that floor even if he doesn't teleport, which nullifies the Angel Room chance boosts and can cause him to teleport into a Devil Room instead of an Angel Room on the 6th use.

SmallIsaac.png Rooms SmallIsaac.png

Unlocked Added in Afterbirth Added in Afterbirth †
Boss Room Icon.png
Boss Room
Mini-Boss Room Icon.png
Mini-Boss Room
Curse Room Icon.png
Curse Room
Sacrifice Room Icon.png
Sacrifice Room
Room 1x1 small.png
Room 1x1.png
Grave Room
Locked Added in Repentance
Treasure Room Icon.png
Treasure Room
Shop Icon.png
Library Icon.png
Planetarium Icon.png
Slotted Arcade Icon.png
Barred Challenge Room Icon.png
Challenge Room
Boss Challenge Room Icon.png
Boss Challenge Room
Double-locked Vault Icon.png
Dice Room Icon.png
Dice Room
Double-boarded Bedroom Icon.png Bedroom2 Icon.png
Hidden Added in Repentance
Secret Room Icon.png
Secret Room
Super Secret Room Icon.png
Super Secret Room
Super Secret Room Icon.png
Crawl Space
Super Secret Room Icon.png
Black Market
Super Secret Room Icon.png
Ultra Secret Room Icon.png
Ultra Secret Room
Post-boss Added in Afterbirth
Devil Room Icon.png
Devil Room
Angel Room Icon.png
Angel Room
Super Secret Room Icon.png
Boss Rush
Super Secret Room Icon.png
Blue Womb Entrance
The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth The Binding of Isaac: Rebirth
Achievements Achievements Attributes Attributes Bosses Bosses TarotCard.png Cards and Runes Challenges Challenges Chapters Chapters
Characters Characters MainPageBabies.png Co-op Items Items Item pools Item pools Monsters Monsters Objects Objects
Pickups Pickups Pills Pills Rooms Rooms Seeds Seeds Transformations Transformations Trinkets Trinkets