Binding of Isaac: Rebirth Wiki

Added in Repentance
Questionmarkisaac.png For another Angel item that gives damage and homing with a similar name, see Sacred Heart.

Sacred Orb is an unlockable passive item added in The Binding of Isaac: Repentance.


  • Prevents low-quality items from appearing, greatly increasing the quality of items received from all item pools.
    • Items with a quality of 0-1 are automatically rerolled.
    • Items with a quality of 2 have a 33% chance to be automatically rerolled.
    • Quest items cannot be rerolled.
  • This item belongs to the Seraphim set. Collecting three items from this set will transform Isaac into an angel.


  • Due to being quality 0, Skatole Skatole cannot be obtained from Shell Game.png Shell Games after Sacred Orb has been picked up.


  • Crooked Penny Crooked Penny/Diplopia Diplopia: No effect. The chance of quality 2 items being rerolled does not increase.
  • Dice Bag Dice Bag: The one-time-use dice given by this trinket are not affected.
  • Lemegeton Lemegeton: Generated items are affected by Sacred Orb.
  • Modeling Clay Modeling Clay: Temporary items generated by this trinket are affected by Sacred Orb.

In-game Footage[]


  • The design of the Sacred Orb seems to be based upon a globus cruciger, lit. "cross-bearing orb", a Christian symbol of authority.
  • This item is a stronger version of the mechanics of Tainted Lost Tainted Lost. Its unlock method is unusual, as most other tainted characters have items based on their mechanics unlocked by defeating Delirium Delirium instead of The Beast The Beast.