Binding of Isaac: Rebirth Wiki
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Added in Afterbirth

Rune Bag is an unlockable passive item added in the Binding of Isaac: Afterbirth expansion.

Effects[]

  • Spawns a familiar that drops a random rune after clearing enough rooms.
    • Removed in Repentance Runes are dropped alternating every 5 or 6 rooms.
    • Added in Repentance Runes are dropped alternating every 7 or 8 rooms.

Notes[]

  • Removed in Repentance If there are no runes unlocked, it will drop cards instead.
  • Added in Repentance Rune Bag will also drop Soul Stones if any have been unlocked.
  • Added in Repentance If not every rune is unlocked, it will drop a Rune Shard Rune Shard in place of the corresponding rune.

Synergies[]

  • BFFS! BFFS!: The drop rate is improved to every 4-5 rooms.
    • Added in Repentance The drop rate is improved to every 6 rooms.

In-game Footage[]

Trivia[]

This item is the rune counterpart to Bomb Bag Bomb Bag, Mystery Sack Mystery Sack, Sack of Pennies Sack of Pennies, and Added in Afterbirth †Sack of Sacks Sack of Sacks.

Seeds[]

PC Added in Repentance H46A 1PJE (Treasure room adjacent to spawn)

Switch Greed mode only 9XX3 HWL2 (First Golden Treasure Room)

Bugs[]

Bug Bug! If one half of Tainted Lazarus Tainted Lazarus holds this item, the Rune Bag will always drop the same rune for the whole run.


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