Rune Bag

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Rune   Bag
Item icon
Item altar
"Rune generator"
Table dividing line 1.png
Item ID
Table dividing line 2.png
Table dividing line 3.png
Collection Grid
Added in Afterbirth † / Removed in Repentance(page 4, column 4, row 2)
Removed in Afterbirth †(page 4, column 4, row 2)
Added in Repentance(page 4, column 5, row 2)
Unlock Method
Rune Bag Defeat Isaac as Lilith
Added in Afterbirth

Rune Bag is an unlockable passive item added in the Binding of Isaac: Afterbirth expansion.

Effects[edit | edit source]

  • Spawns a familiar that drops a random rune alternatingly every 5 or 6 rooms.
    • If there are no runes unlocked, it will drop cards instead.

Synergies[edit | edit source]

  • 15►BFFS! BFFS!: The familiar drops runes alternatingly every 4 or 5 rooms.

In-game Footage[edit | edit source]

Seeds[edit | edit source]

Switch Greed mode only 9XX3 HWL2 (First Golden Treasure Room)

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