Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Razor Blade is an unlockable activated item.


  • On use, takes a full red heart of health and grants +1.2 damage for the current room.


  • Added in Afterbirth Eve Eve starts with this item after unlocking it and donating 439 coins to the Greed Machine.
    • Removed in Repentance Both conditions must be met for Eve to hold it; donating 439 coins before defeating Satan with Eve will wrongly state on Eve's profile on the Character Selection Screen that she has it equipped.
      • Added in Repentance Eve now starts with the Razor Blade if unlocked from the Greed Machine, even if Satan has not been defeated with Eve.
  • If Isaac doesn't have a full Red Heart or a filled Bone Heart, then Soul, Black, and empty Bone Hearts are taken instead.
  • The effect stacks with itself and Red Patch Red Patch, which provides a similar benefit.
  • Using this item does not affect Devil or Angel room chances.
  • Using this item as The Lost The Lost will result in death.
  • When picked up, Isaac's tears turn red, though this change is purely cosmetic.
  • The Razor Blade prioritizes Red Hearts first.
    • Using the Razor blade grants Isaac the regular immunity frames upon usage; this allows Isaac to enter cursed rooms without using soul hearts should he have them.
  • Using this item in the Greed mode Ultra Greed boss room will result in Isaac losing 2-4 coins and dropping 1-3 pennies on the floor similar to being hit by any of the greed enemies.


  • Removed in Repentance15►Isaac's Heart Isaac's Heart: Isaac cannot take damage from the Razor Blade, allowing for infinite uses of the item.
  • 15►Old Bandage Old Bandage / Added in Afterbirth †15►Shard of Glass Shard of Glass: Isaac has a chance to drop a red heart while using the item.
  • Added in RepentancePanic Button Panic Button: Self-damage occurs before enemy damage, making it almost impossible to lose Angel or Devil chance.
  • Removed in Repentance15►The Polaroid The Polaroid: Isaac takes no damage while invincible, allowing for repeated free uses of the item.
  • 15►The Wafer The Wafer: Isaac loses half a heart instead of a full heart.
  • 15►Whore of Babylon Whore of Babylon: The Razor Blade can be used to activate this item's effect by doing enough damage to get Isaac down to half a red heart (or one red heart as Eve), providing a big damage boost for the current room at the cost of health.


  • Added in Repentance15►Book of Virtues Book of Virtues: Spawns red wisps in the middle ring. Wisps have higher health.
  • Added in Afterbirth15►Car Battery Car Battery: No effect.
  • Added in Repentance Shield/Invulnerability: Will not protect against this item's damage.
  • Added in RepentanceTainted Samson Tainted Samson: Using this item can make Tainted Samson unkillable, as his Berserk timer gains time when damaged, and he can't die from lack of red hearts during the rage.

In-game Footage[]


  • This item is used in Darkness Falls (challenge #4).
  • The item itself is a reference to the act of cutting one's self, usually at the wrists, to inflict self-harm or to commit suicide by loss of blood.
  • Isaac's appearance after using the item is just like the Dople.
  • In the original The Binding of Isaac, Razor Blade was unlocked by defeating Mom's Heart/It Lives as Eve.


Bug Bug! As Eve, there is a very unlikely chance that using this to activate Whore of Babylon will not activate it, despite being at the correct health to do so.