Binding of Isaac: Rebirth Wiki

Razor Blade is an unlockable activated item.



  • Added in Afterbirth Eve Eve starts with this item after unlocking it and donating 439 coins to the Greed Donation Machine.png Greed Donation Machine.
    • Removed in Repentance Both conditions must be met for Eve to hold it; donating 439 coins before defeating Satan Satan with Eve will wrongly state on Eve's profile on the Character Selection Screen that she has it equipped.
      • Added in Repentance Eve now starts with the Razor Blade if unlocked from the Greed Machine, even if Satan has not been defeated with Eve.
  • If Isaac doesn't have a full Red Heart Red Heart or a filled Added in Afterbirth † Bone Heart Bone Heart, then Soul Heart Soul Hearts, Black Heart Black Hearts, and empty Bone Hearts are taken instead.
  • The effect stacks with itself and Red Patch Red Patch, which provides a similar benefit.
  • Using this item does not affect Devil Room Devil Room/Angel Room Angel Room chances.
  • Using this item as The Lost The Lost will result in death.
  • When picked up, Isaac's tears turn red, though this change is purely cosmetic.
  • The Razor Blade prioritizes Red Hearts first.
    • Using the Razor blade grants Isaac the regular immunity frames upon usage; this allows Isaac to enter cursed rooms without using soul hearts should he have them.
  • Using this item in the Added in Afterbirth Ultra Greed Ultra Greed boss room will result in Isaac losing 2-4 coins and dropping 1-3 pennies on the floor similar to being hit by any of the greed enemies.


  • Added in RepentanceBook of Virtues Book of Virtues: Spawns red wisps in the middle ring. Wisps have higher health.
  • Removed in RepentanceIsaac's Heart Isaac's Heart: Isaac cannot take damage from the Razor Blade, allowing for infinite uses of the item.
  • Old Bandage Old Bandage / Added in Afterbirth †Shard of Glass Shard of Glass: Isaac has a chance to drop a red heart while using the item.
  • Added in RepentancePanic Button Panic Button: Self-damage occurs before enemy damage, making it almost impossible to lose Angel or Devil chance.
  • Removed in RepentanceThe Polaroid The Polaroid: Isaac takes no damage while invincible, allowing for repeated free uses of the item.
  • The Wafer The Wafer: Isaac loses half a heart instead of a full heart.
  • Whore of Babylon Whore of Babylon: The Razor Blade can be used to activate this item's effect by doing enough damage to get Isaac down to half a red heart (or one red heart as Eve), providing a big damage boost for the current room at the cost of health.
  • Added in RepentanceBirthright Birthright & Judas Judas: Actives the effect of The Necronomicon The Necronomicon alongside its normal effect.


In-game Footage[]


  • This item is used in Darkness Falls (challenge #4).
  • The item itself is a reference to the act of cutting one's self, usually at the wrists, to inflict self-harm or to commit suicide by loss of blood.
  • Isaac's appearance after using the item is just like the Dople Dople.
  • In the original The Binding of Isaac, Razor Blade was unlocked by defeating Mom's Heart Mom's Heart/ It Lives It Lives as Eve Eve.


Bug Bug! As Eve, there is a very unlikely chance that using this to activate Whore of Babylon will not activate it, despite being at the correct health to do so.