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Returns Isaac to the beginning of the run in Chapter 1, with all stat boosts, items, pickups, and trinkets intact, similar to a Victory Lap. Unlike a Victory Lap, however, no effects are applied after a certain number of uses, and the timer is not reset.
Notes
Angel Rooms once again become possible to appear even if the player has made a previous devil deal.
The chance for a Planetarium to appear can once again be increased above 1% without a Telescope Lens, even if the player has previously entered a Planetarium.
If the Donation Machine was jammed before usage, it will no longer be jammed.
True Co-Op players can be spawned in at the first room after using the R Key.
If used in a run while achievements and character unlocks are enabled, they will still be enabled after use. Similarly, if these are disabled because the player is in a Victory Lap or seeded run, they will remain disabled after use.
Beware that using R Key during a Victory Lap will reset the lap counter to 0, as though every Victory Lap is considered part of the same run. Shops will appear as normal, and no items will be removed upon starting the next lap. However, the character will remain The Lost if it had been changed, and the game will remain on Hard difficulty.
In scenarios where R Key can be purchased, it uniquely costs 99 coins instead of 15.
This rule does not apply to the extra shop created by Member Card.
This rule also does not apply to devil deals spawned by A Pound of Flesh.
Despite this, using IX - The Hermit? on R Key will still only spawn 15 coins.
In Greed mode, using the item after breaking the Greed Donation Machine will fix the machine, while also preserving the coin total the machine had before breaking.
While difficult, it is possible to use R Key while swapping it out with another active, letting you bring a different active item to the beginning of the run.
This item is a reference to how holding down the R key on PC will restart a run.
This item is very similar to Clone from Enter the Gungeon. The only difference is that R Key is an activated item while Clone is a passive item that activates upon death.
Bugs
Bug!
If Sprinkler is used on the room the R Key is used in, the sprinkler will come with Isaac to the starting room.
Bug!
If you use the R Key then spawn in a True Co-Op player and restart the game, the Co-Op players' active item and health will disappear.