Binding of Isaac: Rebirth Wiki
Binding of Isaac: Rebirth Wiki

Added in Repentance

R Key is an activated item added in The Binding of Isaac: Repentance.



  • Angel Room Angel Rooms once again become possible to appear even if the player has made a previous devil deal.
  • The chance for a Planetarium Planetarium to appear can once again be increased above 1% without a Telescope Lens Telescope Lens, even if the player has previously entered a Planetarium.
  • If the Donation Machine was jammed before usage, it will no longer be jammed.
  • If used in a run while achievements and character unlocks are enabled, they will still be enabled after use. Similarly, if these are disabled because the player is in a Victory Lap or seeded run, they will remain disabled after use.
  • The timer and score do NOT reset.
  • Item pools are NOT reset.
  • The 13 pill pool does NOT reset, unlike with a victory lap.
  • Key Piece 1 Key Piece 1 and Key Piece 2 Key Piece 2 may also be obtained again, even if already consumed in Chest Chest or Dark Room Dark Room to unlock Mega Satan's door.
  • Knife Piece 1 Knife Piece 1 and Knife Piece 2 Knife Piece 2 may also be obtained again.
  • When used in Ascent or Home Home, Isaac will instead be sent to the Ascent version of Chapter 1. However, the run will restart from there (the ascent sequence ends when R Key is used).
  • In scenarios where R Key can be purchased, it uniquely costs 99 coins instead of 15.
    • This rule does not apply to the extra shop created by Member Card Member Card.
  • If Sprinkler Sprinkler is used on the final room in greed mode and the R Key is used, the sprinkler/s will come with Isaac to the starting room.


  • Book of Virtues Book of Virtues: Will spawn a single, normal wisp.
  • Broken Remote Broken Remote: Isaac will start on a random room on the first floor. This combo can also lead to a game crash.


  • This item is a reference to how holding down the R key on PC will continually restart a run, effectively guaranteeing a good starting room. Eventually.
  • This item is very similar to Clone from Enter the Gungeon. The only difference is that R Key is an activated item while Clone is a passive item that activates upon death.


PC MD1N AZQD (Eden starting item)

PC M0G1 MAE9 (Cellar I Secret Room, east of start)

PC DL4R GT7N (Caves I XL, south-east of start)

PC ACBD AQAM (Catacombs II Secret Room, south and west of start)

PC 30MF ZWMT (Corpse II Secret Room, 4 east 1 north of start, right-hand side item)