Binding of Isaac: Rebirth Wiki
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Purist is challenge #20. This challenge is unique because Isaac starts with no items. The goal is to defeat Boss Mom's Heart ingameMom's Heart or Boss It Lives ingameIt Lives. This Challenge is unlocked after defeating Boss Mom ingameMom for the first time.

Difficulty[ | ]

Because there are no Treasure RoomTreasure Rooms, it is harder to find items. While this is standard for most challenges, Isaac also doesn't start with any items.

Strategy[ | ]

  • Other special rooms become much more important, with Devil RoomDevil Rooms and Angel RoomAngel Rooms becoming even more valuable than on an average run.
  • Cards such as Credit CardCredit Card and items such as (except in Rebirth)Collectible Diplopia iconDiplopia, (in Afterbirth † and Repentance)Collectible Coupon iconCoupon and (in Afterbirth † and Repentance)Collectible Mr. ME! iconMr. ME! can be used for the ShopShop and Devil Room items, with Diplopia cloning the items, and Credit Card/Coupon allowing the item(s) to be taken for free. Neither option stops Angel Rooms from appearing.
  • BombBombs are much more valuable when hunting for Secret RoomSecret Rooms as these can provide free items.
  • (except in Repentance) Curse RoomCurse Rooms guarantee damage and can lower the chances of Devil Rooms. However, if Isaac has a full Soul HeartSoul Heart, Black HeartBlack Heart, or (in Afterbirth † and Repentance) Bone HeartBone Heart, the reward can outweigh the damage and still allow Isaac to access a Devil Room. Alternatively, wait to enter the Curse Room until after visiting the Devil Room.
  • Collectible The Bible iconThe Bible can be used to instantly win the boss fights against Boss Mom ingameMom, which can be used to preserve key health, and Boss Mom's Heart ingameMom's Heart/ Boss It Lives ingameIt Lives, which will complete the challenge.

Reward[ | ]


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