Pupula Duplex is a passive item added in The Binding of Isaac: Afterbirth.
Effects[]
- Grants spectral tears.
- Tear size multiplier: 2x.
- Despite their crescent shape, the tears are still considered round hitbox-wise.
Synergies[]
Godhead: The damaging aura benefits from the increased size significantly.
Interactions[]
- Brimstone: No effect on Brimstone.
- Azazel: Also does not affect Azazel's mini-brimstone.
- The Ludovico Technique: Only tear appearance changes, no tear size up.
- Mom's Knife: No effect on Mom's Knife.
- My Reflection: Tears will spin like boomerangs, purely cosmetic effect.
- Spirit Sword: No effect.
- Tech X: No effect on Tech X.
- Technology: Lasers become spectral.
- Laser beams are thicker in terms of width.
In-game Footage[]
Trivia[]
- "Pupula Duplex" is said to be a condition in which a person has two irises and two pupils in one eye, without any actual recorded cases. An actual rare medical condition similar to it exists, called polycoria.
- This item's icon is similar to Diplopia.
Seeds[]
PC HN4T QMN7 (First floor Treasure Room)
PC 
HLTD B7WD (Treasure Room adjacent to spawn)
PC XVA6 BQFC (First floor Treasure Room)
Switch 
C6VD 4WXP (First Golden Treasure Room)
 The Binding of Isaac: Rebirth
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