Binding of Isaac: Rebirth Wiki
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Proptosis is a passive item.

Effects

  • (except in Repentance) Doubles Isaac's damage stat.
  • (in Repentance) +0.5 damage.
  • Tear size multiplier: 2x.
  • (except in Repentance) The tears shrink and lose damage the farther they travel.
  • (in Repentance) The tears shrink and lose damage the more time they stay airborne, starting at 3x damage at point blank range. After 0.8 seconds, they deal no damage at all.

Notes

  • (except in Repentance) Effective range of Isaac's tears now also depends on the damage, as they can shrink out of existence before their air time runs out.
  • (in Repentance) Since tears run out of damage after 0.8 seconds (48 frames), shot speed is the only stat that determines the effective range of Isaac's tears. Damage and range don't affect the travel distance at all.
  • (in Repentance) Approximately 2.08% damage is lost per frame. This means at approximately 0.53 seconds (32 frames) Isaac's tears will deal the normal amount of damage.
  • (except in Repentance) Tear size increasing items also increase the maximum distance before its disappearance, but the damage dealt can go below original at the extreme.
  • (except in Repentance) Does not affect Character Azazel iconAzazel short-ranged Collectible Brimstone iconBrimstone unless the range stat is extremely high.

Synergies

  • Collectible Anti-Gravity iconAnti-Gravity: The tears will not decrease in size or damage until they start moving, making this excellent against enemies that chase Isaac.
    • Anti-Gravity + (in Repentance)Collectible Eye of the Occult iconEye of the Occult: Lets Isaac maintain the full 3× damage multiplier while controlling his tears.
  • Collectible Brimstone iconBrimstone: Retains the double damage effect without losing damage over range.
    • (except in Rebirth) Damage is doubled again for a total of 4x next to Isaac, but quickly drops further along the beam, at about 0.8x per tile of distance.
    • (in Repentance) The beam does 6x damage at point blank range.
  • (except in Repentance) Collectible Dr. Fetus iconDr. Fetus/Collectible Epic Fetus iconEpic Fetus: Doubles damage with no penalty for distance.
    • (in Repentance) Triples/quadruples damage respectively.
  • Collectible Godhead iconGodhead: The damaging halo shrinks with the tears.
  • Collectible A Lump of Coal iconA Lump of Coal: Proptosis scales with Isaac's damage while the Lump of Coal does not. At base damage, the Lump of Coal will approximately negate the damage lost over distance, but with increased damage, tears still do more damage up close.
    • A Lump of Coal + Collectible The Ludovico Technique iconThe Ludovico Technique: The controlled tear has full Proptosis damage buff, (except in Repentance) no matter how far it is from Isaac. (in Repentance) Very slightly decreases damage from far away.
  • Collectible Mom's Knife iconMom's Knife: The Knife damage is (except in Repentance) doubled ((in Repentance) tripled), regardless of range.
  • Collectible Polyphemus iconPolyphemus: Tears do massive damage and carry with leftover damage while still shrinking.
  • Collectible Technology iconTechnology/Collectible Technology 2 iconTechnology 2: Doubles damage.
    • (except in Rebirth) The beam decreases in damage and width the farther it travels. Tears become virtually powerless across large rooms like the Boss Rush and the Hush fight.
    • (in Repentance) The beams do 6x damage at point blank range.
  • (except in Rebirth)Collectible Tech X iconTech X: Ring size and damage is substantially increased, but decreases as the ring travels further from Isaac.
  • (in Afterbirth †)Collectible Trisagion iconTrisagion: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.
    • (in Repentance) Damage slightly increased, beam damage is doubled. Blasts lose no power with distance.
  • (in Repentance)Collectible Bird's Eye iconBird's Eye: Size and damage of fires is increased, but does not decrease with range.

Interactions

  • (except in Rebirth)Collectible Athame iconAthame/(except in Rebirth)Collectible Maw Of The Void iconMaw Of The Void: The ring is much larger and deals 1.5× damage.
    • (in Afterbirth † and Repentance) The ring deals normal damage.
    • (in Repentance) The ring is now normal size.
  • (in Afterbirth † and Repentance)Collectible Compound Fracture iconCompound Fracture/Collectible Cricket's Body iconCricket's Body/Collectible The Parasite iconThe Parasite: Tears will often disappear before they can burst. Tears created from bursts will also shrink, but due to their already low range, the difference may not be noticeable.
  • (in Afterbirth † and Repentance)Collectible Flat Stone iconFlat Stone: At base range and tear size, tears will bounce twice against the floor and then disappear.
  • (in Repentance)Collectible Immaculate Heart iconImmaculate Heart: Tears that appear around Isaac disappear quickly.
  • Collectible Ipecac iconIpecac: Tears almost disappear completely but are still able to do massive damage.
    • (in Repentance) Tears no longer deal massive damage at the end of the arch. Damage decreases rapidly with range.
  • Isaac's Heart is a very good item to have, as you can run up to most enemies to deal maximum damage to them with little downside
  • (in Afterbirth † and Repentance)Collectible Lachryphagy iconLachryphagy: Tears disappear too quickly to be fed.
  • Collectible The Ludovico Technique iconThe Ludovico Technique: The closer the tear floats to Isaac, the larger it is. The farther away, the smaller it becomes.
  • Collectible Monstro's Lung iconMonstro's Lung/(in Afterbirth † and Repentance)Collectible Lead Pencil iconLead Pencil: Tears will disappear at different distances depending on how big they were when fired.
  • Collectible My Reflection iconMy Reflection: Tears disappear before they can return to Isaac.
  • (in Afterbirth † and Repentance)Collectible Pop! iconPop!: Tears will disappear extremely quickly after being fired.
  • (in Repentance)Collectible Saturnus iconSaturnus The ring tears from Saturnus disappear nearly instantly upon entering a room.
  • Collectible Soy Milk iconSoy Milk: Very poor combination. Tears disappear nearly instantly in front of Isaac, decreasing his range and damage to nearly nothing.
    • (in Repentance) Tears no longer disappear instantly. Range is only minimally shorter.

In-game Footage

Trivia

  • Eye proptosis is a condition resulting in forward displacement and entrapment of the eye from behind by the eyelids. The condition is also known as eye dislocation and eye luxation.


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