Binding of Isaac: Rebirth Wiki

Proptosis is a passive item.


  • Removed in Repentance Doubles Isaac's damage stat.
  • Added in Repentance +0.5 damage.
  • Tear size multiplier: 2x.
  • Removed in Repentance The tears shrink and lose damage the farther they travel.
  • Added in Repentance The tears shrink and lose damage the more time they stay airborne, starting at 3x damage at point blank range. After 0.8 seconds, they deal no damage at all.


  • Removed in Repentance Effective range of Isaac's tears now also depends on the damage, as they can shrink out of existence before their air time runs out.
  • Added in Repentance Since tears run out of damage after 0.8 seconds (48 frames), shot speed is the only stat that determines the effective range of Isaac's tears. Damage and range don't affect the travel distance at all.
  • Added in Repentance Approximately 2.08% damage is lost per frame. This means at approximately 0.53 seconds (32 frames) Isaac's tears will deal the normal amount of damage.
  • Removed in Repentance Tear size increasing items also increase the maximum distance before its disappearance, but the damage dealt can go below original at the extreme.
  • The item has the opposite effect of the item A Lump of Coal A Lump of Coal, which makes Isaac deal more damage from farther away.
  • Removed in Repentance Does not affect Azazel Azazel short-ranged Brimstone Brimstone unless the range stat is extremely high.


  • Anti-Gravity Anti-Gravity: The tears will not decrease in size or damage until they start moving, making this excellent against enemies that chase Isaac.
    • Anti-Gravity + Added in RepentanceEye of the Occult Eye of the Occult: Lets Isaac maintain the full 3× damage multiplier while controlling his tears.
  • Brimstone Brimstone: Retains the double damage effect without losing damage over range.
    • Added in Afterbirth Damage is doubled again for a total of 4x next to Isaac, but quickly drops further along the beam, at about 0.8x per tile of distance.
    • Added in Repentance The beam does 6x damage at point blank range.
  • Removed in Repentance Dr. Fetus Dr. Fetus/Epic Fetus Epic Fetus: Doubles damage with no penalty for distance.
    • Added in Repentance Triples/quadruples damage respectively.
  • Godhead Godhead: The damaging halo shrinks with the tears.
  • A Lump of Coal A Lump of Coal: Proptosis scales with Isaac's damage while the Lump of Coal does not. At base damage, the Lump of Coal will approximately negate the damage lost over distance, but with increased damage, tears still do more damage up close.
    • A Lump of Coal + The Ludovico Technique The Ludovico Technique: The controlled tear has full Proptosis damage buff, Removed in Repentance no matter how far it is from Isaac. Added in Repentance Very slightly decreases damage from far away.
  • Mom's Knife Mom's Knife: The Knife damage is Removed in Repentance doubled (Added in Repentance tripled), regardless of range.
  • Polyphemus Polyphemus: Tears do massive damage and carry with leftover damage while still shrinking.
  • Technology Technology/Technology 2 Technology 2: Doubles damage.
    • Added in Afterbirth The beam decreases in damage and width the farther it travels. Tears become virtually powerless across large rooms like the Boss Rush and the Hush fight.
    • Added in Repentance The beams do 6x damage at point blank range.
  • Added in AfterbirthTech X Tech X: Ring size and damage is substantially increased, but decreases as the ring travels further from Isaac.
  • Added in Afterbirth † / Removed in RepentanceTrisagion Trisagion: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.
    • Added in Repentance Damage slightly increased, beam damage is doubled. Blasts lose no power with distance.
  • Added in RepentanceBird's Eye Bird's Eye: Size and damage of fires is increased, but does not decrease with range.


  • Added in AfterbirthAthame Athame/Added in AfterbirthMaw of the Void Maw of the Void: The ring is much larger and deals 1.5× damage.
    • Added in Afterbirth † The ring deals normal damage.
    • Added in Repentance The ring is now normal size.
  • Added in Afterbirth †Compound Fracture Compound Fracture/Cricket's Body Cricket's Body/The Parasite The Parasite: Tears will often disappear before they can burst. Tears created from bursts will also shrink, but due to their already low range, the difference may not be noticeable.
  • Added in Afterbirth †Flat Stone Flat Stone: At base range and tear size, tears will bounce twice against the floor and then disappear.
  • Added in RepentanceImmaculate Heart Immaculate Heart: Tears that appear around Isaac disappear quickly.
  • Ipecac Ipecac: Tears almost disappear completely but are still able to do massive damage.
    • Added in Repentance Tears no longer deal massive damage at the end of the arch. Damage decreases rapidly with range.
  • Isaac's Heart is a very good item to have, as you can run up to most enemies to deal maximum damage to them with little downside
  • Added in Afterbirth †Lachryphagy Lachryphagy: Tears disappear too quickly to be fed.
  • The Ludovico Technique The Ludovico Technique: The closer the tear floats to Isaac, the larger it is. The farther away, the smaller it becomes.
  • Monstro's Lung Monstro's Lung/Added in Afterbirth †Lead Pencil Lead Pencil: Tears will disappear at different distances depending on how big they were when fired.
  • My Reflection My Reflection: Tears disappear before they can return to Isaac.
  • Added in Afterbirth †Pop! Pop!: Tears will disappear extremely quickly after being fired.
  • Added in RepentanceSaturnus Saturnus The ring tears from Saturnus disappear nearly instantly upon entering a room.
  • Soy Milk Soy Milk: Very poor combination. Tears disappear nearly instantly in front of Isaac, decreasing his range and damage to nearly nothing.
    • Added in Repentance Tears no longer disappear instantly. Range is only minimally shorter.

In-game Footage[]


  • Eye proptosis is a condition resulting in forward displacement and entrapment of the eye from behind by the eyelids. The condition is also known as eye dislocation and eye luxation.


PC Removed in Repentance CMTS HNLP (Treasure Room adjacent to spawn)

PC Removed in Repentance 1SKS ZMYW (Treasure Room adjacent to spawn)

PC Added in Afterbirth / Removed in Repentance GDD6 7YNH (Treasure Room adjacent to spawn, Burning Basement)

PC Added in Repentance Normal and hard modes only 6QN8 VV6L (Treasure Room adjacent to spawn, Burning Basement)

PS4 BZZ7 DWY3 (Treasure Room adjacent to spawn)

3DS HAPT EHDH (First floor Treasure Room)

Switch L79D L9S8 (Treasure Room adjacent to spawn)