Binding of Isaac: Rebirth Wiki

Prayer Card is an activated item.

Effects[ | ]

Notes[ | ]

  • If used after clearing a floor, before proceeding to the next one, it guarantees a new Heart Container every floor.
  • Since it adds the eternal heart directly to the health bar instead of spawning it on the floor, the item is useless for Character Keeper iconKeeper.

Synergies[ | ]

  • (in Repentance)Collectible Book of Virtues iconBook of Virtues: Spawns white, heart-shaped wisps in the inner ring. Wisps' tears have 0.75 shot speed. The wisps' tears effectively act as though they have Collectible Sacred Heart iconSacred Heart.
    • The wisps have two possible sizes. The bigger ones seem to spawn if using Prayer Card gives Isaac another Heart Container.
  • (except in Rebirth)Collectible Car Battery iconCar Battery: Grants one full Heart Container upon use.
  • (in Repentance) Character Tainted Eden iconTainted Eden: Health ups granted by eternal hearts are not rerolled when Tainted Eden takes damage.

Interactions[ | ]

  • Character Tainted Magdalene iconTainted Magdalene: Doesn't benefit from her passive ability, giving only 1 Eternal Heart as usual.

In-game Footage[ | ]

Gallery[ | ]

Trivia[ | ]

  • In the Christian tradition, holy cards or prayer cards are small, devotional pictures mass-produced for the use of the faithful. They usually depict a religious scene or a saint in an image about the size of a playing card. The opposite side typically contains a prayer, some of which promise an indulgence for its recitation.
  • The design on the Prayer Card appears to be of the painting Our Lady of Guadalupe.