Polyphemus is a passive item.
- Greatly increased damage:
- Tears down:
- Tears fired per second * 0.42.
- If a tear kills an enemy, the tear travels on with any leftover damage.
- Polyphemus is a special item.
- Dr. Fetus: Increases tear delay, and after the first bomb explodes, a second bomb appears where the first one exploded, doing roughly half the damage of the first.
- The Inner Eye/ Mutant Spider: The tear rate is not lowered further, but the effect on damage becomes a flat +5 bonus instead.
- The Forgotten: The Forgotten's bone club becomes massive. It deals very high damage but has a very low swing rate.
- Rock Bottom: Allows Isaac to keep his previous fire rate in addition to the massive damage boost.
- Shard of Glass: The rapidly spawning red tears do full damage.
- Haemolacria: The main tear retains the semi-piercing ability and may not burst when hitting a weaker enemy. Split tears do not semi-pierce.
- Lachryphagy: Greatly increases how big the fed tear can grow.
- Lost Contact: Isaac's tears will block enemy shots and continue, but lose 10 damage. If the tear had less than 10 damage left, it disappears.
- Piercing tears: Semi-piercing is replaced by proper piercing, with no loss of damage on any enemy contact.
- Polyphemus: No further effect when multiple copies are acquired.
- Much like other eye-altering passive items, Polyphemus has a unique appearance on The Forgotten, appearing as an empty eye socket.
- Polyphemus, ancient Greek for "The much vaunted", is a Cyclops. He is the son of Poseidon and the sea nymph Thoosa. This item is a reference to the cyclops named Polyphemus from the poem by Homer called "The Great Odyssey"
- This item is used in Slow Roll (challenge #15).
PC 01LE JSFZ (Treasure Room adjacent to spawn)
PC CRCR 2DRH (Treasure Room north of spawn)
PC Z9EF 3B2H (Treasure Room adjacent to spawn)
XboxOne 8T4Q JVMT (Treasure Room adjacent to spawn)
PC KWG7 MXZR (Treasure Room adjacent to spawn)
PC 4S8J GX6L (Treasure Room adjacent to spawn)
PC NKV1 BPSK (Treasure Room adjacent to spawn)
PC 6DA4 KK71 (Treasure Room adjacent to spawn)
PS4 0ZT7 0K1A (First floor Treasure Room)
Vita YAXZ H2WD (Treasure Room adjacent to spawn)
3DS WARH B6XF (Treasure Room adjacent to spawn)
3DS 3KDZ DYK1 (First floor Treasure Room; Curse of the Blind)
3DS 919A H73A (Treasure Room adjacent to spawn)
PS4 9SSM BWNL (First floor Treasure Room)
PS4 X02A WEJQ (First floor Treasure Room, go up then clear that room and polyphemus will be awaiting your arrival)
PC V49A SVM7 (Go down)
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