Binding of Isaac: Rebirth Wiki

(in Afterbirth † and Repentance)

Polydactyly is a passive item added in The Binding of Isaac: Afterbirth †.

Effects[ | ]

  • Allows Isaac to carry two cards, pills, or any combination of both.
  • Spawns one random card, rune, or pill.

Interactions[ | ]

In-game Footage[ | ]

Trivia[ | ]

  • Polydactyly is a birth defect affecting people born with extra amounts of fingers or toes than is normal.