Binding of Isaac: Rebirth Wiki

Added in Afterbirth †

Poke Go is a passive item added in The Binding of Isaac: Afterbirth †.



  • The effect is not activated upon entering the main room of Greed Mode, neither when fighting the waves, making it nearly useless.
  • Multiple friendly enemies can spawn at the same time.
  • For enemies that spawn other enemies, the spawned enemies will also be friendly.
  • Enemy variants may spawn.


  • Added in RepentanceEraser Eraser: Enemies erased via Eraser will never spawn again. This can be a detriment if Vises are erased, as it greatly reduces the usefulness of Poke Go.

In-game Footage[]


  • The item is a reference to Pokémon GO: an augmented reality mobile game in which Pokémon are generated around the player as they walk around in real life.
    • The pickup quote is a shortened version of "Gotta catch 'em all!", one of the series' marketing slogans.
    • "A charmed (enemy) appears!" is a reference to the phrase "A wild Pokémon appears!" from the games.
  • Poke Go was originally an unofficial item which was supposed to showcase the modding capabilities of Afterbirth+ in the PAX 2016 livestream. However, all items included in the demo were later added to the final game.
  • Since Poke Go is simply part of Isaac's imagination, Edmund McMillen confirmed that Isaac therefore technically knew about Pokémon Go.