Placenta is a passive item.
Effects[ | ]
- Grants one full Red Heart container when picked up.
- Isaac has a 50% chance to regenerate a Half Red Heart every time the in-game timer hits a new minute (00:01:00, 00:02:00, etc).
- Heals 1 additional Red Heart when picked up.
Notes[ | ]
- This item can rarely drop from polyps.
- The regeneration can happen multiple times in the same room, so there is no need to move between rooms to continue regeneration.
- However, regeneration does not occur when standing in a Crawl Space.
- Regeneration will only occur when Isaac has Red Heart containers or something equivalent:
- Keeper's and Tainted Keeper's coin hearts will regenerate, one coin at a time.
- Bone Hearts regenerate like red hearts.
- Consequently, characters with no applicable health -- ???, The Lost, Dark Judas, Tainted Bethany, Tainted Judas, and Tainted Lost—do not benefit from the effect.
Synergies[ | ]
- Blood Oath: With enough patience, health can be safely restored each floor by waiting in the starting room.
- Gnawed Leaf: Regeneration works while turned to stone, allowing Isaac to become invincible and regenerate while in any room.
- Sanguine Bond: Can be used indefinitely with placenta’s regen. Also works with normal sacrifice rooms
- Sharp Plug: With enough patience, any active item can be reused indefinitely.
Interactions[ | ]
- Maggy's Bow: No effect on regen.
In-game Footage[ | ]
Trivia[ | ]
- A Placenta is an organ that forms from the mother's uterus during pregnancy that supports the unborn child during development until it is expelled during childbirth. In some cultures, it is a common practice for the mother and/or child to eat the expelled placenta.
- This, like many other things Isaac does, is medically inadvisable (without proper preparation methods).
Bugs[ | ]
Bug! | Going into a Ventricle Razor portal at the same time the effect of Placenta is triggered will cause the effect to trigger in rapid succession, effectively healing Isaac to full health. |
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The Binding of Isaac: Rebirth |
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