Pickups

Pickups are minor items that can be found around the game.

Pickups can be found from any of the following sources:

Semi-randomly being placed in rooms. Found inside of Chests. Dropped by any kind of Beggar.

Dropped after clearing a Room. Found after blasting Tinted Rocks. Dropped by various Slot Machines.

Dropped after defeating a Champion Monster. Bought in Shops. Generated as part of an item effect.

Hearts

Coins

Bombs

Keys

Batteries

Pills

Cards

Chests

Sacks

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Red Hearts

Red Hearts are the standard HP for most characters and can be found in half-heart, full-heart, or double-heart varieties. The player cannot have more red hearts than heart containers.

Half Red Heart

Replenishes half a red heart of Isaac's health.

1+1 Free Heart

Replenishes two red hearts of Isaac's health.

Notes

• Isaac can't take red hearts if all of his heart containers are full.
• If Isaac takes a heart that would heal him for more than his current maximum health (for example, taking a red heart when he is only missing half a red heart worth of health), the excessive health will be wasted.
• Unless an item effect specifically states it, a red heart always has the chance to be replaced by a Soul, Black, or Eternal heart.
• Red heart pickups created by item, card, or pill effects can be forced to be spawned as Black or Eternal hearts instead by using the item, card, or pill in a relevant Super Secret Room.

Soul Hearts

Soul Hearts are light-blue hearts that are added to the end of the health bar. Soul Hearts are not permanent; once lost, they cannot be replenished, although new ones may be added.

Black Hearts

Black Hearts are mostly identical to Soul Hearts, with one key difference; a black heart, when fully lost, will damage all enemies in the room, similar to The Necronomicon's effect.

Notes

• If Isaac has red hearts and half a soul heart, taking a full heart of damage will not remove any red hearts.
• If Isaac's health bar is filled with soul hearts, picking up a black heart will replace the topmost soul heart.
• If Isaac's topmost heart is a half Soul Heart, collecting a Black Heart will complete it into a whole soul heart, and add half a Black heart.
  • Likewise, collecting a Soul Heart with half a Black Heart left will complete the Black Heart, and add half a Soul Heart.
• If Isaac's health bar is filled up to 11 1/2 (Soul/Black) hearts with the last one being half a Black Heart, picking up a Black Heart will fill that one and convert a full Soul Heart to a Black Heart (therefore adding half a Black Heart and converting a Soul Heart).
• Losing Soul Hearts does not count as Red Heart damage for the purposes of determining Devil or Angel Room spawn chances.
• Standard Soul Heart pickups have a chance to be replaced by Black Hearts.

Eternal Hearts

Eternal Hearts are the second rarest variation of a heart. They always appear as half-hearts and, once picked up, can transform into a new heart container in two ways: either by collecting a second Eternal Heart, or by traveling to a new floor.

• An Eternal Heart appends to the end of the health bar. This will usually be the rightmost heart container, but can also be the leftmost Soul Heart (or Black Heart) if there are no containers.
  • This means that an Eternal Heart will not be counted against the regular cap of 12 hearts.
    • If Isaac has 12 red heart containers and travels to a new floor with an eternal heart, Isaac will heal one red heart but will not gain another heart container. If Isaac is at full health, the eternal heart will simply disappear.
  • Like Soul Hearts, an Eternal Heart cannot be replenished when lost (without picking up a new one).
  • It will be used up the first time Isaac takes red heart damage. This means that using a Blood Donation Machine or activated items like the Razor Blade will drain the Eternal Heart, even if Isaac has full health and/or Soul Hearts.
    • Eternal Hearts are not lost by taking red heart damage if Isaac has no red heart containers.
  • Health removal from Devil Room items will not drain an Eternal Heart. Rather, the Eternal Heart is appended onto the end of the next red heart. However, if after a Deal with the Devil Isaac will have no red hearts, Soul Hearts, or Black Hearts, Isaac will die; half an Eternal Heart cannot keep Isaac alive by itself.

Gold Hearts Template:Afterbirth

Gold Hearts are the rarest variation of a heart. They are unlocked by completing the challenge XXXXXXXXL. They always appear as full hearts and, once picked up, drop money next time Isaac loses a Heart. A Golden Heart appends to the end of the health bar, surrounding it in a golden glow.

Notes

• Gold Hearts are depleted when Isaac takes damage and loses the rightmost heart, but do not prevent the surrounding heart from being depleted.
• Can be found in Greed Mode without unlocking them, unknown if this is a bug or intentional as Greed Mode is heavily focused on money.
• A Gold Heart will not be counted against the regular cap of 12 hearts.
• Like Soul Hearts and Eternal Hearts, a Gold Heart cannot be replenished when lost (without picking up a new one).
• Gold Hearts are not lost by taking red heart damage by using a Blood Donation Machine or activated items like the Razor Blade.
• If Isaac has a Gold Heart and gains a heart container while at 12 soul or black hearts, the Gold Heart will disappear although its effect will still activate.

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Coins serve as the currency for shops, the payment for the Donation Machine in shops, and payment for the slot machines, fortune telling machines, shell game, and beggars. They are also consumed to use a few activated items (most notably Magic Fingers and Portable Slot). They will naturally drop as a Penny, a Nickel, and rarely a Dime. Template:Afterbirth Picking up a coin has a chance to increase luck by 1 if Lucky Pennies has been unlocked.

Penny

1+1 Free Penny

A 1+1 Free Penny is worth 2 pennies.

Nickel

A Nickel is worth 5 pennies.

Dime

A Dime is worth 10 pennies.

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Bombs are used to damage enemies, destroy rocks, and open up regular doors and secret rooms. When spawned, there is a possibility for it to be a Troll Bomb instead.

1+1 Free Bomb

Adds 2 bombs on pickup.

Troll Bombs

Bomb pickups have a chance to spawn as a Troll Bomb. Normal Troll Bombs cannot be picked up and are already lit, so be wary of the imminent explosion. Trolling is the internet term for tricking or messing with one psychologically. This is why this item is called a "Troll bomb."

Mega Troll Bombs

Mega Troll Bombs are another bomb variation that behaves similarly to regular Troll Bombs, but come with additional hazards:

• They are bigger and have a larger blast radius (like bombs upgraded with Mr. Mega).
• If nearby, they actively chase Isaac before exploding (as if under the influence of Magneto).

Gold Bombs Template:Afterbirth

Gold bombs will not add to the player's bomb count, but when picked up they will give the player unlimited bombs for the duration of the current floor. They are unlocked by completing the challenge Blue Bomber.

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Keys are used to gain entry to many of the game's rooms, as well as golden chests.

Key Ring

Adds 2 keys on pickup.

Golden Keys

When picked up, a golden key will not add to the player's key count. It will, however, allow the player to open any locked door, key block, or chest without spending any keys for the duration of the floor, even if the player has 0 keys. There is a 1/50 chance for any given key pickup to be a golden key.

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Little Battery

Little Battery (or Lil Battery as referred by Edmund) will fully charge your activated item upon pickup.

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See Pills.

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See Cards and Runes.

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See Chests.

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Mystery Sack Template:Afterbirth

The Mystery Sack will spawn 1-4 pickups upon touching it.

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