Panic Button

Trinket Icon
Pickup Quote	"Push in case of emergency"
Entity ID	5.350.149

Panic Button is a trinket added in The Binding of Isaac: Repentance.

Effects

• Activates Isaac's active item just before damage would be taken.
  • This still uses the item's charges so if the item is not charged, the trinket will do nothing.
  • Single-use items will be consumed.

Notes

• Because the automatic item activation takes place just before taking would-be damage, this trinket becomes very powerful when holding damage-negating active items.
• Taking damage from explosions, spikes and spike rocks, spiked/mimic chests, the stomp attacks from Mom and Satan, Whippers and their variants, brimstone lasers (including angel lasers), self-damage items, Devil Beggars, Blood Donation Machines, and Confessionals will not trigger the effect.
• Super-charged items will use both of their charges. This is NOT an effect by Mom's Box or the Golden Trinket variant.
• Does not activate items in a consumable slot (such as Tainted Bethany's Lemegeton or dice items granted by Dice Bag).

Interactions

• Any self-damaging item: Self-damage occurs before enemy damage, making it almost impossible to lose Devil/Angel Room chances.
  • For self-damaging items that deals only half a heart damage (such as Kamikaze!), before chapter 4, it will also reduce enemy damage to half a heart, similarly to The Wafer.
• Blood Rights: Triggers the effect on hit, at the cost of every hit making Isaac take full-heart damage.
• Butter Bean / Wait What?: Isaac farts before being hit, knocking back enemies and projectiles.
• Dull Razor: Activates the item and gives Isaac invincibility frames before being hit, making it work similarly to Holy Mantle every two rooms. If combined with 9 Volt or AAA Battery, works every room, just like Holy Mantle.
• Glowing Hour Glass: If consumed with Void, every time Isaac is hit, if it's charged, he is sent back to the previous room without taking damage.
• Holy Mantle: Does not stop the trinket from activating, making Isaac still take damage from items such as IV Bag, while bypassing Holy Mantle's shield.
  • The Lost can die this way should he carry self damaging items at the time of the hit.
• How to Jump: Makes Isaac immune to contact and tear damage while moving.
• IV Bag: Upon getting hit, activates the IV Bag instead, causing red heart damage and producing money.
• Kamikaze!: Causes a highly-damaging explosion to occur every time Isaac is hit, similarly to Swallowed M80.
• Razor Blade: Isaac gains a damage boost every time he's hit, acting similarly to Red Patch, at the cost of every hit making Isaac take full-heart damage.
• Spin to Win: Has a chance to spawn additional wheels upon taking damage that last only for the current room. This is most likely a bug.
• Stitches: Isaac will teleport before damage is taken, making him much harder to hit.
• Tainted Forgotten: Triggers his active item whenever the body touches something that would damage The Soul, regardless of damage taken.
• Telekinesis: Automatically blocks any incoming shots, but the push is not strong enough to prevent contact damage.
• Yum Heart: Since the effect is triggered before taking damage, Panic Button will waste the charge with no benefit unless Isaac is already missing Red health.

In-game footage

The Binding of Isaac: Rebirth
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