Pandora's Box

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Pandora's Box is an unlockable activated item.

Effect[edit | edit source]

  • Upon use, spawns certain pickups or items depending on the floor it is used on. Pandora's Box disappears after use.
Normal Mode Added in AfterbirthGreed Mode Items/Pickups
Basement Basement I
Cellar Cellar I
Added in Afterbirth Burning Basement Burning Basement I
Added in Repentance Downpour Downpour I
Added in Repentance Dross Dross I
Added in Afterbirth / Removed in Afterbirth † Basement Basement 2 Soul Hearts
Basement Basement II
Cellar Cellar II
Added in Afterbirth Burning Basement Burning Basement II
Added in Repentance Downpour Downpour II
Added in Repentance Dross Dross II
Added in Afterbirth / Removed in Afterbirth † Caves Caves
Added in Afterbirth † Basement Basement
Added in Repentance Cellar Cellar
Added in Repentance Burning Basement Burning Basement
2 bombs and 2 keys
Caves Caves I
Catacombs Catacombs I
Added in Afterbirth Flooded Caves Flooded Caves I
Added in Repentance Mines Mines I
Added in Repentance Ashpit Ashpit I
Added in Afterbirth / Removed in Afterbirth † Depths Depths 1 Boss Room item
Caves Caves II
Catacombs Catacombs II
Added in Afterbirth Flooded Caves Flooded Caves II
Added in Repentance Mines Mines II
Added in Repentance Ashpit Ashpit II
Added in Afterbirth / Removed in Afterbirth † Womb Womb
Added in Afterbirth † Caves Caves
Added in Repentance Catacombs Catacombs
Added in Repentance Flooded Caves Flooded Caves
1 Boss Room item and 2 Soul Hearts
Depths Depths I
Necropolis Necropolis I
Added in Afterbirth Dank Depths Dank Depths I
Added in Repentance Mausoleum Mausoleum I
Added in Repentance Gehenna Gehenna I
Added in Afterbirth / Removed in Afterbirth † Sheol Sheol 4 Soul Hearts
Depths Depths II
Necropolis Necropolis II
Added in Afterbirth Dank Depths Dank Depths II
Added in Repentance Mausoleum Mausoleum II
Added in Repentance Gehenna Gehenna II
Added in Afterbirth / Removed in Afterbirth † The Shop The Shop
Added in Afterbirth † Depths Depths
Added in Repentance Necropolis Necropolis
Added in Repentance Dank Depths Dank Depths
20 Coins
Utero Utero I
Womb Womb I
Added in Afterbirth Scarred Womb Scarred Womb I
Added in Repentance Corpse Corpse I
Added in Afterbirth / Removed in Afterbirth † Ultra Greed Ultra Greed
Added in Afterbirth † Womb Womb
Added in Repentance Utero Utero
Added in Repentance Scarred Womb Scarred Womb
2 Boss Room items
Utero Utero II
Womb Womb II
Added in Afterbirth Scarred Womb Scarred Womb II
Added in Repentance Corpse Corpse II
--- 15►The Bible The Bible
Added in Afterbirth ??? ??? --- Nothing
Added in Afterbirth † The Void The Void --- Nothing
Sheol Sheol Added in Afterbirth † Sheol Sheol 1 Devil Room item and 1 Black Heart
Dark Room Dark Room --- Nothing
Added in Afterbirth † Unlocks 15►Moving Box Moving Box
Cathedral Cathedral --- 1 Angel Room item and 1 Eternal Heart
Chest Chest Added in Afterbirth † The Shop The Shop
Added in Afterbirth † Ultra Greed Ultra Greed
1 Coin
Added in Repentance Home Home --- Added in Repentance15►Red Key Red Key

Notes[edit | edit source]

  • XL floors count as the first floor for Pandora's Box.
  • If Pandora's Box attempts to spawn an item from an item pool that is empty, it will instead spawn an item from the Treasure Room pool.
  • Removed in Repentance Using theAdded in Afterbirth? Card ? Card with Pandora's Box will consume both the card and the item with no additional benefit.
    • Added in Repentance ? Card now activates the item without consuming it, allowing for potential multiple uses. Added in Afterbirth †15►Tarot Cloth Tarot Cloth, however, has no effect.
  • Pandora's Box is not doubled by Added in Afterbirth15►Car Battery Car Battery.

Synergies[edit | edit source]

  • Added in RepentanceStrange Key Strange Key: Instead of its normal effect, Pandora's Box spawns six items from random pools. Both items are consumed.

In-game Footage[edit | edit source]

Unlockable Achievements[edit | edit source]

Gallery[edit | edit source]

Notes[edit | edit source]

  • The rewards for Greed Mode changed in patch v1.06.J168.

Trivia[edit | edit source]

  • In Greek legend, Pandora's Box was a box containing all of the evils of the world, given to the first woman created, who opened it, releasing every evil unto the land, besides the last spirit, Elpis, the Spirit of Hope.

Seeds[edit | edit source]

PC Normal and hard modes only 1TNY 7MJ0 (Curse Room adjacent to spawn)

PC Added in Afterbirth † Normal mode only VKPS 2M1F (Shop in 1st floor)

PC Added in Afterbirth † Hard mode only 1TNY 7MJO (Second floor curse room)


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